Unicentric Castleman's Disease Arising from an Intrapulmonary Lymph Node
Castleman's disease is an uncommon lymphoproliferative disorder of unknown etiology, most often involving the mediastinum. It has 2 distinct clinical forms: unicentric and multicentric. Unicentric Castleman's disease arising from an intrapulmonary lymph node is rare, and establishing a pre...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2013/289089 |
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| author | Hideki Ota Hideki Kawai Tsubasa Matsuo |
| author_facet | Hideki Ota Hideki Kawai Tsubasa Matsuo |
| author_sort | Hideki Ota |
| collection | DOAJ |
| description | Castleman's disease is an uncommon lymphoproliferative disorder of unknown etiology, most often involving the mediastinum. It has 2 distinct clinical forms: unicentric and multicentric. Unicentric Castleman's disease arising from an intrapulmonary lymph node is rare, and establishing a preoperative diagnosis of this disease is very difficult mainly due to a lack of specific imaging features. We report a case of intrapulmonary unicentric Castleman's disease in an asymptomatic 19-year-old male patient who was accurately diagnosed by preoperative computed tomography (CT). The mass was incidentally found on a routine chest X-ray. A subsequent dynamic CT showed a well-defined, hypervascular, soft-tissue mass with small calcifications located in the perihilar area of the right lower lung. Three-dimensional CT (3D-CT) angiography indicated that the mass was receiving its blood supply through a vascular network at its surface that originated from 2 right bronchial arteries. The clinical history and CT findings were consistent with a diagnosis of unicentric Castleman's disease, and we safely and successfully removed the tumor via video-assisted thoracoscopic surgical lobectomy. This case shows that the imaging characteristics of these rare tumors on contrast-enhanced CT combined with 3D-CT angiography can be helpful in reliably establishing a correct preoperative diagnosis. |
| format | Article |
| id | doaj-art-56475352d01f4e8c84aa9eb078061ad3 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-56475352d01f4e8c84aa9eb078061ad32025-02-03T05:51:31ZengWileyCase Reports in Surgery2090-69002090-69192013-01-01201310.1155/2013/289089289089Unicentric Castleman's Disease Arising from an Intrapulmonary Lymph NodeHideki Ota0Hideki Kawai1Tsubasa Matsuo2Department of Thoracic Surgery, Akita Red Cross Hospital, Akita 010-1495, JapanDepartment of Thoracic Surgery, Akita Red Cross Hospital, Akita 010-1495, JapanDepartment of Thoracic Surgery, Akita Red Cross Hospital, Akita 010-1495, JapanCastleman's disease is an uncommon lymphoproliferative disorder of unknown etiology, most often involving the mediastinum. It has 2 distinct clinical forms: unicentric and multicentric. Unicentric Castleman's disease arising from an intrapulmonary lymph node is rare, and establishing a preoperative diagnosis of this disease is very difficult mainly due to a lack of specific imaging features. We report a case of intrapulmonary unicentric Castleman's disease in an asymptomatic 19-year-old male patient who was accurately diagnosed by preoperative computed tomography (CT). The mass was incidentally found on a routine chest X-ray. A subsequent dynamic CT showed a well-defined, hypervascular, soft-tissue mass with small calcifications located in the perihilar area of the right lower lung. Three-dimensional CT (3D-CT) angiography indicated that the mass was receiving its blood supply through a vascular network at its surface that originated from 2 right bronchial arteries. The clinical history and CT findings were consistent with a diagnosis of unicentric Castleman's disease, and we safely and successfully removed the tumor via video-assisted thoracoscopic surgical lobectomy. This case shows that the imaging characteristics of these rare tumors on contrast-enhanced CT combined with 3D-CT angiography can be helpful in reliably establishing a correct preoperative diagnosis.http://dx.doi.org/10.1155/2013/289089 |
| spellingShingle | Hideki Ota Hideki Kawai Tsubasa Matsuo Unicentric Castleman's Disease Arising from an Intrapulmonary Lymph Node Case Reports in Surgery |
| title | Unicentric Castleman's Disease Arising from an Intrapulmonary Lymph Node |
| title_full | Unicentric Castleman's Disease Arising from an Intrapulmonary Lymph Node |
| title_fullStr | Unicentric Castleman's Disease Arising from an Intrapulmonary Lymph Node |
| title_full_unstemmed | Unicentric Castleman's Disease Arising from an Intrapulmonary Lymph Node |
| title_short | Unicentric Castleman's Disease Arising from an Intrapulmonary Lymph Node |
| title_sort | unicentric castleman s disease arising from an intrapulmonary lymph node |
| url | http://dx.doi.org/10.1155/2013/289089 |
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