Extensive Spiculated Follicular Porokeratosis With Alopecia: A Case Report
ABSTRACT Follicular porokeratosis (FPK) is a rare subtype of porokeratosis. Follicular porokeratosis mainly occurs in men and may be localized or diffuse. Involvement of the scalp is rarely reported, and we found only one case of alopecia due to scalp FPK. Diabetes mellitus has not been reported in...
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Wiley
2025-01-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.70100 |
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| author | Mitra Abdolvand Roya Radanfar Mozhdeh Sepaskhah Fatemeh Sari Aslani Mojgan Akbarzadeh Jahromi |
| author_facet | Mitra Abdolvand Roya Radanfar Mozhdeh Sepaskhah Fatemeh Sari Aslani Mojgan Akbarzadeh Jahromi |
| author_sort | Mitra Abdolvand |
| collection | DOAJ |
| description | ABSTRACT Follicular porokeratosis (FPK) is a rare subtype of porokeratosis. Follicular porokeratosis mainly occurs in men and may be localized or diffuse. Involvement of the scalp is rarely reported, and we found only one case of alopecia due to scalp FPK. Diabetes mellitus has not been reported in association with FPK We report a 35‐year‐old diabetic woman that presented with brown follicular keratotic papules and spicules involving the scalp, face, trunk, and extremities, accompanied by scalp alopecia. The differential diagnoses were lichen planopilaris, papular eczema, and phrynoderma. Histopathologic examination of skin punch biopsies revealed the follicle‐centered cornoid lamella as the feature of FPK. The patient was treated with oral isotretinoin, and the lesions improved partially within 6 weeks of follow‐up. Follicular porokeratosis might be considered among the differential diagnoses of keratotic papules (with or without spicules) and in the cases of alopecia with keratotic papules. Diabetes mellitus may be associated with FPK. |
| format | Article |
| id | doaj-art-56348ef8a176487692edd8320b0c3ff1 |
| institution | Kabale University |
| issn | 2050-0904 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj-art-56348ef8a176487692edd8320b0c3ff12025-01-24T05:08:46ZengWileyClinical Case Reports2050-09042025-01-01131n/an/a10.1002/ccr3.70100Extensive Spiculated Follicular Porokeratosis With Alopecia: A Case ReportMitra Abdolvand0Roya Radanfar1Mozhdeh Sepaskhah2Fatemeh Sari Aslani3Mojgan Akbarzadeh Jahromi4Department of Dermatology, School of Medicine Shiraz University of Medical Sciences Shiraz IranDepartment of Dermatology, School of Medicine Shiraz University of Medical Sciences Shiraz IranMolecular Dermatology Research Center, Department of Dermatology, School of Medicine Shiraz University of Medical Sciences Shiraz IranMolecular Dermatology Research Center, Department of Pathology, School of Medicine Shiraz University of Medical Sciences Shiraz IranDepartment of Pathology, School of Medicine Shiraz University of Medical Sciences Shiraz IranABSTRACT Follicular porokeratosis (FPK) is a rare subtype of porokeratosis. Follicular porokeratosis mainly occurs in men and may be localized or diffuse. Involvement of the scalp is rarely reported, and we found only one case of alopecia due to scalp FPK. Diabetes mellitus has not been reported in association with FPK We report a 35‐year‐old diabetic woman that presented with brown follicular keratotic papules and spicules involving the scalp, face, trunk, and extremities, accompanied by scalp alopecia. The differential diagnoses were lichen planopilaris, papular eczema, and phrynoderma. Histopathologic examination of skin punch biopsies revealed the follicle‐centered cornoid lamella as the feature of FPK. The patient was treated with oral isotretinoin, and the lesions improved partially within 6 weeks of follow‐up. Follicular porokeratosis might be considered among the differential diagnoses of keratotic papules (with or without spicules) and in the cases of alopecia with keratotic papules. Diabetes mellitus may be associated with FPK.https://doi.org/10.1002/ccr3.70100alopeciacase reportsdermoscopypathologyporokeratosisscalp |
| spellingShingle | Mitra Abdolvand Roya Radanfar Mozhdeh Sepaskhah Fatemeh Sari Aslani Mojgan Akbarzadeh Jahromi Extensive Spiculated Follicular Porokeratosis With Alopecia: A Case Report Clinical Case Reports alopecia case reports dermoscopy pathology porokeratosis scalp |
| title | Extensive Spiculated Follicular Porokeratosis With Alopecia: A Case Report |
| title_full | Extensive Spiculated Follicular Porokeratosis With Alopecia: A Case Report |
| title_fullStr | Extensive Spiculated Follicular Porokeratosis With Alopecia: A Case Report |
| title_full_unstemmed | Extensive Spiculated Follicular Porokeratosis With Alopecia: A Case Report |
| title_short | Extensive Spiculated Follicular Porokeratosis With Alopecia: A Case Report |
| title_sort | extensive spiculated follicular porokeratosis with alopecia a case report |
| topic | alopecia case reports dermoscopy pathology porokeratosis scalp |
| url | https://doi.org/10.1002/ccr3.70100 |
| work_keys_str_mv | AT mitraabdolvand extensivespiculatedfollicularporokeratosiswithalopeciaacasereport AT royaradanfar extensivespiculatedfollicularporokeratosiswithalopeciaacasereport AT mozhdehsepaskhah extensivespiculatedfollicularporokeratosiswithalopeciaacasereport AT fatemehsariaslani extensivespiculatedfollicularporokeratosiswithalopeciaacasereport AT mojganakbarzadehjahromi extensivespiculatedfollicularporokeratosiswithalopeciaacasereport |