1α,25(OH)2D3 reverses exhaustion and enhances antitumor immunity of human cytotoxic T cells
Background Epidemiological surveys have revealed that low serum vitamin D level was correlated with increased risk of tumors. Dysfunctional T cells in patients with tumor are characterized as exhausted with high levels of immune checkpoint receptors (ICRs). However, whether the reduced level of vita...
Saved in:
| Main Authors: | Peng Li, Hua Zhang, Xiao Wang, Biyun Chen, Ke Li, Zhinan Yin, Xinhai Zhu, Guangchao Cao, Ruan Wu, Wenhui Yuan, Guodong Sun, Xichun Xia, Ligong Lu, Yunfei Gao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2022-03-01
|
| Series: | Journal for ImmunoTherapy of Cancer |
| Online Access: | https://jitc.bmj.com/content/10/3/e003477.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Maternal and neonatal 25-OH cholecalciferol (25-OH-CC) levels
by: Şinasi Özsoylu
Published: (2014-06-01) -
GP73 reinforces cytotoxic T-cell function by regulating HIF-1α and increasing antitumor efficacy
by: Xiaoli Yang, et al.
Published: (2025-01-01) -
Relationship between 25(OH)D2, 25(OH)D3 and core symptoms in autism spectrum disorder
by: Liu Jia, et al.
Published: (2025-08-01) -
Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy
by: Xia Liu, et al.
Published: (2022-10-01) -
Importance of including O cells in reverse grouping in detection of Bombay phenotype (Oh)
by: Dr. Shamsuz Zaman, et al.
Published: (2014-09-01)