Influence of plasma on the physical properties of ointments with quercetin
Effects of two independent variables - the content of quercetin (0 or 1 or 1.5 or 5 %) and the content of plasma (0 or 2 or 4 or 6 %) - on the organoleptic properties and rheological parameters of model formulations prepared on an amphiphilic base were estimated. The consistency of all ointments was...
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| Format: | Article |
| Language: | English |
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Sciendo
2017-12-01
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| Series: | Acta Pharmaceutica |
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| Online Access: | https://doi.org/10.1515/acph-2017-0038 |
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| author | Szulc-Musioł Beata Dolińska Barbara Kołodziejska Justyna Ryszka Florian |
| author_facet | Szulc-Musioł Beata Dolińska Barbara Kołodziejska Justyna Ryszka Florian |
| author_sort | Szulc-Musioł Beata |
| collection | DOAJ |
| description | Effects of two independent variables - the content of quercetin (0 or 1 or 1.5 or 5 %) and the content of plasma (0 or 2 or 4 or 6 %) - on the organoleptic properties and rheological parameters of model formulations prepared on an amphiphilic base were estimated. The consistency of all ointments was uniform, and the content of quercetin and plasma lay within the predefined range. Tested ointments are non-Newtonian systems. The content of quercetin and plasma was found to have a significant effect on the rheological properties of the ointments. An increase in the content of plasma in ointments was accompanied by a significant increase in their hardness, viscosity and shear stress and a reduction of their spreadability. The best rheological properties were shown by formulation F-3, containing 1.5 % of quercetin and 2 % of plasma. |
| format | Article |
| id | doaj-art-561c22ac7aa248a29f71da0d3e881347 |
| institution | Kabale University |
| issn | 1846-9558 |
| language | English |
| publishDate | 2017-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Pharmaceutica |
| spelling | doaj-art-561c22ac7aa248a29f71da0d3e8813472025-02-02T12:11:59ZengSciendoActa Pharmaceutica1846-95582017-12-0167456957810.1515/acph-2017-0038acph-2017-0038Influence of plasma on the physical properties of ointments with quercetinSzulc-Musioł Beata0Dolińska Barbara1Kołodziejska Justyna2Ryszka Florian3Department of Applied Pharmacy School of Pharmacy and the Division of Laboratory Medicine Medical University of Silesia, PolandDepartment of Applied Pharmacy School of Pharmacy and the Division of Laboratory Medicine Medical University of Silesia, PolandDepartment of Applied Pharmacy Medical University of Łódź, PolandPharmaceutical Research and Production Plant »Biochefa« Sosnowiec, PolandEffects of two independent variables - the content of quercetin (0 or 1 or 1.5 or 5 %) and the content of plasma (0 or 2 or 4 or 6 %) - on the organoleptic properties and rheological parameters of model formulations prepared on an amphiphilic base were estimated. The consistency of all ointments was uniform, and the content of quercetin and plasma lay within the predefined range. Tested ointments are non-Newtonian systems. The content of quercetin and plasma was found to have a significant effect on the rheological properties of the ointments. An increase in the content of plasma in ointments was accompanied by a significant increase in their hardness, viscosity and shear stress and a reduction of their spreadability. The best rheological properties were shown by formulation F-3, containing 1.5 % of quercetin and 2 % of plasma.https://doi.org/10.1515/acph-2017-0038quercetinplasmaointmentrheological property |
| spellingShingle | Szulc-Musioł Beata Dolińska Barbara Kołodziejska Justyna Ryszka Florian Influence of plasma on the physical properties of ointments with quercetin Acta Pharmaceutica quercetin plasma ointment rheological property |
| title | Influence of plasma on the physical properties of ointments with quercetin |
| title_full | Influence of plasma on the physical properties of ointments with quercetin |
| title_fullStr | Influence of plasma on the physical properties of ointments with quercetin |
| title_full_unstemmed | Influence of plasma on the physical properties of ointments with quercetin |
| title_short | Influence of plasma on the physical properties of ointments with quercetin |
| title_sort | influence of plasma on the physical properties of ointments with quercetin |
| topic | quercetin plasma ointment rheological property |
| url | https://doi.org/10.1515/acph-2017-0038 |
| work_keys_str_mv | AT szulcmusiołbeata influenceofplasmaonthephysicalpropertiesofointmentswithquercetin AT dolinskabarbara influenceofplasmaonthephysicalpropertiesofointmentswithquercetin AT kołodziejskajustyna influenceofplasmaonthephysicalpropertiesofointmentswithquercetin AT ryszkaflorian influenceofplasmaonthephysicalpropertiesofointmentswithquercetin |