In Vitro Activities of Sparfloxacin, Ceftriaxone, Penicillin, Tetracycline and Doxycycline against Chlamydia trachomatis and Neisseria gonhorrhoeae
In vitro sparfloxacin was highly active against 223 penicillin-susceptible isolates of Neisseria gonorrhoeae with a 90% minimal inhibitory concentration (MIC90) of 0.004 μg/mL. Resistant strains of N gonorrhoeae totalled 55; 32 were penicillinase-producing and 23 chromosomally resistant. The MIC90 f...
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| Format: | Article |
| Language: | English |
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Wiley
1992-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/1992/743419 |
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| _version_ | 1832547986096259072 |
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| author | Hazel Talbot Barbara Romanowski |
| author_facet | Hazel Talbot Barbara Romanowski |
| author_sort | Hazel Talbot |
| collection | DOAJ |
| description | In vitro sparfloxacin was highly active against 223 penicillin-susceptible isolates of Neisseria gonorrhoeae with a 90% minimal inhibitory concentration (MIC90) of 0.004 μg/mL. Resistant strains of N gonorrhoeae totalled 55; 32 were penicillinase-producing and 23 chromosomally resistant. The MIC90 for these isolates was 0.004 μg/mL and 0.008 μg/mL, respectively. Chlamydia trachomatis was also very susceptible with an MIC50 of 0.063 μg/mL and a 50% minimal bactericidal concentration of 0.032 μg/mL for 11 isolates. |
| format | Article |
| id | doaj-art-560bfaa8bd4941e0b04c26c1575d2379 |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 1992-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-560bfaa8bd4941e0b04c26c1575d23792025-02-03T06:42:28ZengWileyCanadian Journal of Infectious Diseases1180-23321992-01-013311411710.1155/1992/743419In Vitro Activities of Sparfloxacin, Ceftriaxone, Penicillin, Tetracycline and Doxycycline against Chlamydia trachomatis and Neisseria gonhorrhoeaeHazel Talbot0Barbara Romanowski1Clinical Investigation Unit, Sexually Transmitted Disease Control, Alberta Health, Edmonton, Alberta, CanadaClinical Investigation Unit, Sexually Transmitted Disease Control, Alberta Health, Edmonton, Alberta, CanadaIn vitro sparfloxacin was highly active against 223 penicillin-susceptible isolates of Neisseria gonorrhoeae with a 90% minimal inhibitory concentration (MIC90) of 0.004 μg/mL. Resistant strains of N gonorrhoeae totalled 55; 32 were penicillinase-producing and 23 chromosomally resistant. The MIC90 for these isolates was 0.004 μg/mL and 0.008 μg/mL, respectively. Chlamydia trachomatis was also very susceptible with an MIC50 of 0.063 μg/mL and a 50% minimal bactericidal concentration of 0.032 μg/mL for 11 isolates.http://dx.doi.org/10.1155/1992/743419 |
| spellingShingle | Hazel Talbot Barbara Romanowski In Vitro Activities of Sparfloxacin, Ceftriaxone, Penicillin, Tetracycline and Doxycycline against Chlamydia trachomatis and Neisseria gonhorrhoeae Canadian Journal of Infectious Diseases |
| title | In Vitro Activities of Sparfloxacin, Ceftriaxone, Penicillin, Tetracycline and Doxycycline against Chlamydia trachomatis and Neisseria gonhorrhoeae |
| title_full | In Vitro Activities of Sparfloxacin, Ceftriaxone, Penicillin, Tetracycline and Doxycycline against Chlamydia trachomatis and Neisseria gonhorrhoeae |
| title_fullStr | In Vitro Activities of Sparfloxacin, Ceftriaxone, Penicillin, Tetracycline and Doxycycline against Chlamydia trachomatis and Neisseria gonhorrhoeae |
| title_full_unstemmed | In Vitro Activities of Sparfloxacin, Ceftriaxone, Penicillin, Tetracycline and Doxycycline against Chlamydia trachomatis and Neisseria gonhorrhoeae |
| title_short | In Vitro Activities of Sparfloxacin, Ceftriaxone, Penicillin, Tetracycline and Doxycycline against Chlamydia trachomatis and Neisseria gonhorrhoeae |
| title_sort | in vitro activities of sparfloxacin ceftriaxone penicillin tetracycline and doxycycline against chlamydia trachomatis and neisseria gonhorrhoeae |
| url | http://dx.doi.org/10.1155/1992/743419 |
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