Global stability for an SEI epidemiological model with continuous age-structure in the exposed and infectious classes

We study a model of disease transmission with continuous age-structure for latentlyinfected individuals and for infectious individuals. The model is very appropriate fortuberculosis. Key theorems, including asymptotic smoothness and uniform persistence,are proven by reformulating the system as a s...

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Main Author: C. Connell McCluskey
Format: Article
Language:English
Published: AIMS Press 2012-09-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2012.9.819
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author C. Connell McCluskey
author_facet C. Connell McCluskey
author_sort C. Connell McCluskey
collection DOAJ
description We study a model of disease transmission with continuous age-structure for latentlyinfected individuals and for infectious individuals. The model is very appropriate fortuberculosis. Key theorems, including asymptotic smoothness and uniform persistence,are proven by reformulating the system as a system of Volterra integral equations. Thebasic reproduction number $\mathcal{R}_{0}$ is calculated. For $\mathcal{R}_{0}1$, a Lyapunov functionalis used to show that the endemic equilibrium is globally stable amongst solutions forwhich the disease is present. Finally, some special cases are considered.
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spelling doaj-art-5608df143dde4a23874c7398fd085ee92025-01-24T02:07:06ZengAIMS PressMathematical Biosciences and Engineering1551-00182012-09-019481984110.3934/mbe.2012.9.819Global stability for an SEI epidemiological model with continuous age-structure in the exposed and infectious classesC. Connell McCluskey0Department of Mathematics, Wilfrid Laurier University, Waterloo, OntarioWe study a model of disease transmission with continuous age-structure for latentlyinfected individuals and for infectious individuals. The model is very appropriate fortuberculosis. Key theorems, including asymptotic smoothness and uniform persistence,are proven by reformulating the system as a system of Volterra integral equations. Thebasic reproduction number $\mathcal{R}_{0}$ is calculated. For $\mathcal{R}_{0}1$, a Lyapunov functionalis used to show that the endemic equilibrium is globally stable amongst solutions forwhich the disease is present. Finally, some special cases are considered.https://www.aimspress.com/article/doi/10.3934/mbe.2012.9.819global stabilitytuberculosisage-structurelatencyepidemiology.lyapunov functional
spellingShingle C. Connell McCluskey
Global stability for an SEI epidemiological model with continuous age-structure in the exposed and infectious classes
Mathematical Biosciences and Engineering
global stability
tuberculosis
age-structure
latency
epidemiology.
lyapunov functional
title Global stability for an SEI epidemiological model with continuous age-structure in the exposed and infectious classes
title_full Global stability for an SEI epidemiological model with continuous age-structure in the exposed and infectious classes
title_fullStr Global stability for an SEI epidemiological model with continuous age-structure in the exposed and infectious classes
title_full_unstemmed Global stability for an SEI epidemiological model with continuous age-structure in the exposed and infectious classes
title_short Global stability for an SEI epidemiological model with continuous age-structure in the exposed and infectious classes
title_sort global stability for an sei epidemiological model with continuous age structure in the exposed and infectious classes
topic global stability
tuberculosis
age-structure
latency
epidemiology.
lyapunov functional
url https://www.aimspress.com/article/doi/10.3934/mbe.2012.9.819
work_keys_str_mv AT cconnellmccluskey globalstabilityforanseiepidemiologicalmodelwithcontinuousagestructureintheexposedandinfectiousclasses