Protein identification using Cryo-EM and artificial intelligence guides improved sample purification

Protein identification using Cryo-EM and artificial intelligence guides improved sample purification

Protein purification is essential in protein biochemistry, structural biology, and protein design, enabling the determination of protein structures, the study of biological mechanisms, and the characterization of both natural and de novo designed proteins. However, standard purification strategies o...

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Bibliographic Details
Main Authors: Kenneth D. Carr, Dane Evan D. Zambrano, Connor Weidle, Alex Goodson, Helen E. Eisenach, Harley Pyles, Alexis Courbet, Neil P. King, Andrew J. Borst
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Journal of Structural Biology: X
Subjects:
Protein Purification
Contamination
Cryo-Electron Microscopy
Cryo-EM
DLST
Dihydrolipoamide Succinyltransferase
Online Access:http://www.sciencedirect.com/science/article/pii/S2590152425000017
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