RuPhos Pd G4: A catalyst for Suzuki-Miyaura coupling reactions involving 1,2,4-oxadiazoles
The 1,2,4-oxadiazole motif is highly significant in biological studies. An efficient Suzuki-Miyaura coupling methodology has been developed, catalyzed by RuPhos Pd G4, for 1,2,4-oxadiazole substrates This method achieves high yields and clean reactions, featuring a broad substrate scope and straight...
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Elsevier
2025-01-01
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715624006866 |
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author | Deepak Kumar Soumya Singh Ganesh Jaysing Shinde Suryakanta Dalai Abhineet Vermaa Girish Chandra Sharma Mukesh Jangir |
author_facet | Deepak Kumar Soumya Singh Ganesh Jaysing Shinde Suryakanta Dalai Abhineet Vermaa Girish Chandra Sharma Mukesh Jangir |
author_sort | Deepak Kumar |
collection | DOAJ |
description | The 1,2,4-oxadiazole motif is highly significant in biological studies. An efficient Suzuki-Miyaura coupling methodology has been developed, catalyzed by RuPhos Pd G4, for 1,2,4-oxadiazole substrates This method achieves high yields and clean reactions, featuring a broad substrate scope and straightforward gram-scale synthesis. The pathway offers new biologically useful moieties that can be further explored for their potential applications. |
format | Article |
id | doaj-art-55e9bc9508da470b9f29751f90660994 |
institution | Kabale University |
issn | 2211-7156 |
language | English |
publishDate | 2025-01-01 |
publisher | Elsevier |
record_format | Article |
series | Results in Chemistry |
spelling | doaj-art-55e9bc9508da470b9f29751f906609942025-01-29T05:00:49ZengElsevierResults in Chemistry2211-71562025-01-0113101990RuPhos Pd G4: A catalyst for Suzuki-Miyaura coupling reactions involving 1,2,4-oxadiazolesDeepak Kumar0Soumya Singh1Ganesh Jaysing Shinde2Suryakanta Dalai3Abhineet Vermaa4Girish Chandra Sharma5Mukesh Jangir6Department of Applied Sciences, Chemistry, Nims University Rajasthan, Jaipur, India; Jubilant Biosys Ltd., Greater Noida, UP 201310, IndiaDepartment of Chemistry, Institute of Science, Banaras Hindu University, Varanasi 221005, IndiaDepartment of Applied Sciences, Chemistry, Nims University Rajasthan, Jaipur, India; Jubilant Biosys Ltd., Greater Noida, UP 201310, IndiaJubilant Biosys Ltd., Greater Noida, UP 201310, IndiaDepartment of Chemistry, Malaviya National Institute of Technology (MNIT), Jaipur 302017, Rajasthan, IndiaDepartment of Applied Sciences, Chemistry, Nims University Rajasthan, Jaipur, IndiaDepartment of Applied Sciences, Chemistry, Nims University Rajasthan, Jaipur, India; Corresponding author.The 1,2,4-oxadiazole motif is highly significant in biological studies. An efficient Suzuki-Miyaura coupling methodology has been developed, catalyzed by RuPhos Pd G4, for 1,2,4-oxadiazole substrates This method achieves high yields and clean reactions, featuring a broad substrate scope and straightforward gram-scale synthesis. The pathway offers new biologically useful moieties that can be further explored for their potential applications.http://www.sciencedirect.com/science/article/pii/S22117156240068661,2,4-OxadiazoleRuPhos PdG4Suzuki couplingOrganic synthesisCatalyst efficiency |
spellingShingle | Deepak Kumar Soumya Singh Ganesh Jaysing Shinde Suryakanta Dalai Abhineet Vermaa Girish Chandra Sharma Mukesh Jangir RuPhos Pd G4: A catalyst for Suzuki-Miyaura coupling reactions involving 1,2,4-oxadiazoles Results in Chemistry 1,2,4-Oxadiazole RuPhos PdG4 Suzuki coupling Organic synthesis Catalyst efficiency |
title | RuPhos Pd G4: A catalyst for Suzuki-Miyaura coupling reactions involving 1,2,4-oxadiazoles |
title_full | RuPhos Pd G4: A catalyst for Suzuki-Miyaura coupling reactions involving 1,2,4-oxadiazoles |
title_fullStr | RuPhos Pd G4: A catalyst for Suzuki-Miyaura coupling reactions involving 1,2,4-oxadiazoles |
title_full_unstemmed | RuPhos Pd G4: A catalyst for Suzuki-Miyaura coupling reactions involving 1,2,4-oxadiazoles |
title_short | RuPhos Pd G4: A catalyst for Suzuki-Miyaura coupling reactions involving 1,2,4-oxadiazoles |
title_sort | ruphos pd g4 a catalyst for suzuki miyaura coupling reactions involving 1 2 4 oxadiazoles |
topic | 1,2,4-Oxadiazole RuPhos PdG4 Suzuki coupling Organic synthesis Catalyst efficiency |
url | http://www.sciencedirect.com/science/article/pii/S2211715624006866 |
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