Hypothesis on the role of cholesterol crystals in spontaneously ruptured aortic plaques: Potential triggers for inflammation and systemic effects

Cholesterol crystals (CCs) are a key component of atherosclerotic plaques and play a pivotal role in plaque progression, rupture, and the resulting inflammatory responses. CCs emboli trigger proinflammatory cytokines which can potentially lead to organ damage. Spontaneously ruptured aortic plaques (...

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Bibliographic Details
Main Authors: Chikao Yutani, Hirotaka Noda, Nobuzo Iwa, Sei Komatsu, Satoru Takahashi, Yoshiharu Higuchi, Kazuhisa Kodama
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:American Heart Journal Plus
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666602225000102
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