High-throughput strategies for monoclonal antibody screening: advances and challenges

High-throughput strategies for monoclonal antibody screening: advances and challenges

Abstract Antibodies characterized by high affinity and specificity, developed through high-throughput screening and rapid preparation, are crucial to contemporary biomedical industry. Traditional antibody preparation via the hybridoma strategy faces challenges like low efficiency, long manufacturing...

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Bibliographic Details
Main Authors: Xiao-Dong Wang, Bao-Ying Ma, Shi-Ying Lai, Xiang-Jing Cai, Yan-Guang Cong, Jun-Fa Xu, Peng-Fei Zhang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Biological Engineering
Subjects:
High-throughput
Antibody preparation
Display system for antibody libraries
Single B cell antibody
Single-cell sequencing
Online Access:https://doi.org/10.1186/s13036-025-00513-z
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