Prospective Cohort Study on Refractive Changes after Trabeculectomy

We prospectively evaluated refractive changes in the eyes of 97 patients who underwent trabeculectomy at Fukui University Hospital, Fukui, Japan. The primary outcome measure was the refractive change after trabeculectomy. Secondary outcome measures included postoperative complications and prognostic...

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Main Authors: Kentaro Iwasaki, Yoshihiro Takamura, Shogo Arimura, Takahiro Tsuji, Takehiro Matsumura, Makoto Gozawa, Masaru Inatani
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2019/4731653
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author Kentaro Iwasaki
Yoshihiro Takamura
Shogo Arimura
Takahiro Tsuji
Takehiro Matsumura
Makoto Gozawa
Masaru Inatani
author_facet Kentaro Iwasaki
Yoshihiro Takamura
Shogo Arimura
Takahiro Tsuji
Takehiro Matsumura
Makoto Gozawa
Masaru Inatani
author_sort Kentaro Iwasaki
collection DOAJ
description We prospectively evaluated refractive changes in the eyes of 97 patients who underwent trabeculectomy at Fukui University Hospital, Fukui, Japan. The primary outcome measure was the refractive change after trabeculectomy. Secondary outcome measures included postoperative complications and prognostic factors for refractive change. We observed a progressive and significant mean refractive myopic shift of −0.80 D at 12 months after surgery. In phakic eyes, the mean myopic refractive shifts progressed significantly by −0.46 D at 3 months after surgery (P=0.003), by −0.52 D at 6 months (P=0.012), and by −1.31 D at 12 months (P<0.001). In the pseudophakic eyes, we found no significant refraction progression at any of the postsurgery follow-up visits. Our multivariable analyses showed that lens nuclear color grade change was a significant prognostic factor for refractive myopic progression (P<0.001). Trabeculectomy causes refractive myopic progression in phakic eyes. Nuclear sclerotic cataract progression is associated with refractive myopic shift after trabeculectomy. This trail is registered with UMIN000007813.
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issn 2090-004X
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publishDate 2019-01-01
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series Journal of Ophthalmology
spelling doaj-art-55be8bb925874296ac1bcaa2e1bf2f062025-02-03T01:10:27ZengWileyJournal of Ophthalmology2090-004X2090-00582019-01-01201910.1155/2019/47316534731653Prospective Cohort Study on Refractive Changes after TrabeculectomyKentaro Iwasaki0Yoshihiro Takamura1Shogo Arimura2Takahiro Tsuji3Takehiro Matsumura4Makoto Gozawa5Masaru Inatani6Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, JapanDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, JapanDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, JapanDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, JapanDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, JapanDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, JapanDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, JapanWe prospectively evaluated refractive changes in the eyes of 97 patients who underwent trabeculectomy at Fukui University Hospital, Fukui, Japan. The primary outcome measure was the refractive change after trabeculectomy. Secondary outcome measures included postoperative complications and prognostic factors for refractive change. We observed a progressive and significant mean refractive myopic shift of −0.80 D at 12 months after surgery. In phakic eyes, the mean myopic refractive shifts progressed significantly by −0.46 D at 3 months after surgery (P=0.003), by −0.52 D at 6 months (P=0.012), and by −1.31 D at 12 months (P<0.001). In the pseudophakic eyes, we found no significant refraction progression at any of the postsurgery follow-up visits. Our multivariable analyses showed that lens nuclear color grade change was a significant prognostic factor for refractive myopic progression (P<0.001). Trabeculectomy causes refractive myopic progression in phakic eyes. Nuclear sclerotic cataract progression is associated with refractive myopic shift after trabeculectomy. This trail is registered with UMIN000007813.http://dx.doi.org/10.1155/2019/4731653
spellingShingle Kentaro Iwasaki
Yoshihiro Takamura
Shogo Arimura
Takahiro Tsuji
Takehiro Matsumura
Makoto Gozawa
Masaru Inatani
Prospective Cohort Study on Refractive Changes after Trabeculectomy
Journal of Ophthalmology
title Prospective Cohort Study on Refractive Changes after Trabeculectomy
title_full Prospective Cohort Study on Refractive Changes after Trabeculectomy
title_fullStr Prospective Cohort Study on Refractive Changes after Trabeculectomy
title_full_unstemmed Prospective Cohort Study on Refractive Changes after Trabeculectomy
title_short Prospective Cohort Study on Refractive Changes after Trabeculectomy
title_sort prospective cohort study on refractive changes after trabeculectomy
url http://dx.doi.org/10.1155/2019/4731653
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AT takahirotsuji prospectivecohortstudyonrefractivechangesaftertrabeculectomy
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