Nonleukemic Ureteral Granulocytic Sarcoma Presenting with Unilateral Urinary Obstruction and Hematuria

Granulocytic sarcoma is an extramedullary tumor which is composed of myeloblasts and immature myeloid cells. It usually occurs in association with acute myeloid leukemia and most commonly involves skin, soft tissue, lymph nodes, bone, and periosteum. We report a case of isolated ureteral granulocyti...

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Main Authors: Ömer Acar, Tarık Esen, Tülay Tecimer, Mustafa Çetiner, Önder Peker, Ahmet Musaoğlu
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2013/861232
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author Ömer Acar
Tarık Esen
Tülay Tecimer
Mustafa Çetiner
Önder Peker
Ahmet Musaoğlu
author_facet Ömer Acar
Tarık Esen
Tülay Tecimer
Mustafa Çetiner
Önder Peker
Ahmet Musaoğlu
author_sort Ömer Acar
collection DOAJ
description Granulocytic sarcoma is an extramedullary tumor which is composed of myeloblasts and immature myeloid cells. It usually occurs in association with acute myeloid leukemia and most commonly involves skin, soft tissue, lymph nodes, bone, and periosteum. We report a case of isolated ureteral granulocytic sarcoma without hematologic manifestations. Our patient presented with bloody urine and left-sided lumbar pain. Preoperative clinical and radiologic features raised the suspicion of an upper urinary tract transitional cell carcinoma, and he was scheduled for nephroureterectomy. However, perioperative pathologic feedback and the unusual endoscopic appearance of the tumor altered our surgical strategy towards segmental ureterectomy and ureteroneocystostomy. Eventual pathologic diagnosis was granulocytic sarcoma of the ureter. Postoperative workup failed to demonstrate any sign of an accompanying hematologic disorder. He started receiving the chemotherapy protocol of acute myeloblastic leukemia. To our knowledge, this is the first documented case of nonleukemic ureteral granulocytic sarcoma which came to attention due to urologic complaints.
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institution Kabale University
issn 2090-696X
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language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Case Reports in Urology
spelling doaj-art-55a88546dbb54fb988a1d645cd949e742025-02-03T01:09:42ZengWileyCase Reports in Urology2090-696X2090-69782013-01-01201310.1155/2013/861232861232Nonleukemic Ureteral Granulocytic Sarcoma Presenting with Unilateral Urinary Obstruction and HematuriaÖmer Acar0Tarık Esen1Tülay Tecimer2Mustafa Çetiner3Önder Peker4Ahmet Musaoğlu5Department of Urology, VKF American Hospital, Istanbul, TurkeyDepartment of Urology, VKF American Hospital, Istanbul, TurkeyDepartment of Pathology, VKF American Hospital, Istanbul, TurkeySchool of Medicine, Koc University, Istanbul, TurkeyDepartment of Pathology, VKF American Hospital, Istanbul, TurkeyDepartment of Urology, VKF American Hospital, Istanbul, TurkeyGranulocytic sarcoma is an extramedullary tumor which is composed of myeloblasts and immature myeloid cells. It usually occurs in association with acute myeloid leukemia and most commonly involves skin, soft tissue, lymph nodes, bone, and periosteum. We report a case of isolated ureteral granulocytic sarcoma without hematologic manifestations. Our patient presented with bloody urine and left-sided lumbar pain. Preoperative clinical and radiologic features raised the suspicion of an upper urinary tract transitional cell carcinoma, and he was scheduled for nephroureterectomy. However, perioperative pathologic feedback and the unusual endoscopic appearance of the tumor altered our surgical strategy towards segmental ureterectomy and ureteroneocystostomy. Eventual pathologic diagnosis was granulocytic sarcoma of the ureter. Postoperative workup failed to demonstrate any sign of an accompanying hematologic disorder. He started receiving the chemotherapy protocol of acute myeloblastic leukemia. To our knowledge, this is the first documented case of nonleukemic ureteral granulocytic sarcoma which came to attention due to urologic complaints.http://dx.doi.org/10.1155/2013/861232
spellingShingle Ömer Acar
Tarık Esen
Tülay Tecimer
Mustafa Çetiner
Önder Peker
Ahmet Musaoğlu
Nonleukemic Ureteral Granulocytic Sarcoma Presenting with Unilateral Urinary Obstruction and Hematuria
Case Reports in Urology
title Nonleukemic Ureteral Granulocytic Sarcoma Presenting with Unilateral Urinary Obstruction and Hematuria
title_full Nonleukemic Ureteral Granulocytic Sarcoma Presenting with Unilateral Urinary Obstruction and Hematuria
title_fullStr Nonleukemic Ureteral Granulocytic Sarcoma Presenting with Unilateral Urinary Obstruction and Hematuria
title_full_unstemmed Nonleukemic Ureteral Granulocytic Sarcoma Presenting with Unilateral Urinary Obstruction and Hematuria
title_short Nonleukemic Ureteral Granulocytic Sarcoma Presenting with Unilateral Urinary Obstruction and Hematuria
title_sort nonleukemic ureteral granulocytic sarcoma presenting with unilateral urinary obstruction and hematuria
url http://dx.doi.org/10.1155/2013/861232
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AT tarıkesen nonleukemicureteralgranulocyticsarcomapresentingwithunilateralurinaryobstructionandhematuria
AT tulaytecimer nonleukemicureteralgranulocyticsarcomapresentingwithunilateralurinaryobstructionandhematuria
AT mustafacetiner nonleukemicureteralgranulocyticsarcomapresentingwithunilateralurinaryobstructionandhematuria
AT onderpeker nonleukemicureteralgranulocyticsarcomapresentingwithunilateralurinaryobstructionandhematuria
AT ahmetmusaoglu nonleukemicureteralgranulocyticsarcomapresentingwithunilateralurinaryobstructionandhematuria