Adalimumab Induced or Provoked MS in Patient with Autoimmune Uveitis: A Case Report and Review of the Literature
Anti-tumor necrosis factor α (anti-TNF-α) agents have been widely used in the field of autoimmune diseases and have proved decisive efficacy and relative safety. Data concerning their adverse effects has been lately describing central nervous system (CNS) demyelination process at escalating basis. C...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/1423131 |
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| _version_ | 1832558241926610944 |
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| author | Rana Alnasser Alsukhni Ziena Jriekh Yasmin Aboras |
| author_facet | Rana Alnasser Alsukhni Ziena Jriekh Yasmin Aboras |
| author_sort | Rana Alnasser Alsukhni |
| collection | DOAJ |
| description | Anti-tumor necrosis factor α (anti-TNF-α) agents have been widely used in the field of autoimmune diseases and have proved decisive efficacy and relative safety. Data concerning their adverse effects has been lately describing central nervous system (CNS) demyelination process at escalating basis. Case Presentation. A 23-year-old male with autoimmune uveitis and a family history of multiple sclerosis (MS) developed two neurological attacks, after Adalimumab infusion, simultaneously with several cerebral lesions on magnetic resonance imaging (MRI). Hence the diagnosis of Adalimumab induced MS was suspected. Conclusion. This case is reported to tell physicians to be cautious when using anti-TNF-α in patients with family history of MS and to reconsider the risk of MS in patients with autoimmune diseases. |
| format | Article |
| id | doaj-art-559fab34d9104de99b559fa099f1c996 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-559fab34d9104de99b559fa099f1c9962025-02-03T01:32:47ZengWileyCase Reports in Medicine1687-96271687-96352016-01-01201610.1155/2016/14231311423131Adalimumab Induced or Provoked MS in Patient with Autoimmune Uveitis: A Case Report and Review of the LiteratureRana Alnasser Alsukhni0Ziena Jriekh1Yasmin Aboras2Division of Neurology, Department of Internal Medicine, Aleppo University Hospital, Aleppo, SyriaDivision of Rheumatology, Department of Internal Medicine, Aleppo University Hospital, Aleppo, SyriaDivision of Neurology, Department of Internal Medicine, Aleppo University Hospital, Aleppo, SyriaAnti-tumor necrosis factor α (anti-TNF-α) agents have been widely used in the field of autoimmune diseases and have proved decisive efficacy and relative safety. Data concerning their adverse effects has been lately describing central nervous system (CNS) demyelination process at escalating basis. Case Presentation. A 23-year-old male with autoimmune uveitis and a family history of multiple sclerosis (MS) developed two neurological attacks, after Adalimumab infusion, simultaneously with several cerebral lesions on magnetic resonance imaging (MRI). Hence the diagnosis of Adalimumab induced MS was suspected. Conclusion. This case is reported to tell physicians to be cautious when using anti-TNF-α in patients with family history of MS and to reconsider the risk of MS in patients with autoimmune diseases.http://dx.doi.org/10.1155/2016/1423131 |
| spellingShingle | Rana Alnasser Alsukhni Ziena Jriekh Yasmin Aboras Adalimumab Induced or Provoked MS in Patient with Autoimmune Uveitis: A Case Report and Review of the Literature Case Reports in Medicine |
| title | Adalimumab Induced or Provoked MS in Patient with Autoimmune Uveitis: A Case Report and Review of the Literature |
| title_full | Adalimumab Induced or Provoked MS in Patient with Autoimmune Uveitis: A Case Report and Review of the Literature |
| title_fullStr | Adalimumab Induced or Provoked MS in Patient with Autoimmune Uveitis: A Case Report and Review of the Literature |
| title_full_unstemmed | Adalimumab Induced or Provoked MS in Patient with Autoimmune Uveitis: A Case Report and Review of the Literature |
| title_short | Adalimumab Induced or Provoked MS in Patient with Autoimmune Uveitis: A Case Report and Review of the Literature |
| title_sort | adalimumab induced or provoked ms in patient with autoimmune uveitis a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2016/1423131 |
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