The effects of U.V light on mrkA, mrkD genes in local isolates of Klebsiella pneumoniae

Klebsiella pneumoniae is dangerous pathogens that can cause severe diseases. This study included isolation of 50 isolates of K.pneumoniaefrom different clinical sources from different hospitals in Baghdad city, the number and percentage of isolates according to the sources (urine, blood, sputum, bur...

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Main Authors: Ali Hussein Alwan, Sura Mouaid Abass
Format: Article
Language:English
Published: Mustansiriyah University 2017-02-01
Series:Al-Mustansiriyah Journal of Science
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Online Access:http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/32
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author Ali Hussein Alwan
Sura Mouaid Abass
author_facet Ali Hussein Alwan
Sura Mouaid Abass
author_sort Ali Hussein Alwan
collection DOAJ
description Klebsiella pneumoniae is dangerous pathogens that can cause severe diseases. This study included isolation of 50 isolates of K.pneumoniaefrom different clinical sources from different hospitals in Baghdad city, the number and percentage of isolates according to the sources (urine, blood, sputum, burns, ear swabs, pus, wounds and stool ) were 22(44%), 11(22%), 4(8%), 4(8%), 3(6%), 3(6%), 2(4%) and 1(2%) respectively. The ability to form biofilm was carried out using Tissue culture plate methods (-TCP-). The results showed that 80% of the isolates were producer biofilm; the genetic study was used to detect the presence of mrkA, mrkD genes that are believed to be responsible of biofilm production. The ratio was mrkA 87.5% and mrkD 50% before exposure to U.V.light to reduce to 43.7% mrkA and 18.7% mrkD in isolates after exposure to U.V.light source.
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institution OA Journals
issn 1814-635X
2521-3520
language English
publishDate 2017-02-01
publisher Mustansiriyah University
record_format Article
series Al-Mustansiriyah Journal of Science
spelling doaj-art-556e2633bc834fffbbbdc1955ca4b20a2025-08-20T02:26:09ZengMustansiriyah UniversityAl-Mustansiriyah Journal of Science1814-635X2521-35202017-02-0127410.23851/mjs.v27i4.3229The effects of U.V light on mrkA, mrkD genes in local isolates of Klebsiella pneumoniaeAli Hussein Alwan0Sura Mouaid Abass1Department of Biology, College of Science, Al-Mustansiriyah University, Iraq.Department of Biology, College of Science, Al-Mustansiriyah University, Iraq.Klebsiella pneumoniae is dangerous pathogens that can cause severe diseases. This study included isolation of 50 isolates of K.pneumoniaefrom different clinical sources from different hospitals in Baghdad city, the number and percentage of isolates according to the sources (urine, blood, sputum, burns, ear swabs, pus, wounds and stool ) were 22(44%), 11(22%), 4(8%), 4(8%), 3(6%), 3(6%), 2(4%) and 1(2%) respectively. The ability to form biofilm was carried out using Tissue culture plate methods (-TCP-). The results showed that 80% of the isolates were producer biofilm; the genetic study was used to detect the presence of mrkA, mrkD genes that are believed to be responsible of biofilm production. The ratio was mrkA 87.5% and mrkD 50% before exposure to U.V.light to reduce to 43.7% mrkA and 18.7% mrkD in isolates after exposure to U.V.light source.http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/32K.pneumoniae, U.V lights, mrkA, mrkD genes, biofilm formation.
spellingShingle Ali Hussein Alwan
Sura Mouaid Abass
The effects of U.V light on mrkA, mrkD genes in local isolates of Klebsiella pneumoniae
Al-Mustansiriyah Journal of Science
K.pneumoniae, U.V lights, mrkA, mrkD genes, biofilm formation.
title The effects of U.V light on mrkA, mrkD genes in local isolates of Klebsiella pneumoniae
title_full The effects of U.V light on mrkA, mrkD genes in local isolates of Klebsiella pneumoniae
title_fullStr The effects of U.V light on mrkA, mrkD genes in local isolates of Klebsiella pneumoniae
title_full_unstemmed The effects of U.V light on mrkA, mrkD genes in local isolates of Klebsiella pneumoniae
title_short The effects of U.V light on mrkA, mrkD genes in local isolates of Klebsiella pneumoniae
title_sort effects of u v light on mrka mrkd genes in local isolates of klebsiella pneumoniae
topic K.pneumoniae, U.V lights, mrkA, mrkD genes, biofilm formation.
url http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/32
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