Diagnostic Accuracy of 256-Detector Row Computed Tomography in Detection and Characterization of Incidental Pancreatic Cystic Lesions

Purpose. To assess the diagnostic value of 256-detector row MDCT in the characterization of incidentally detected pancreatic cystic lesions (PCLs). Materials and Methods. We retrospectively reviewed 6389 studies performed on a 256-row detector scanner, wherein ≥1 PCLs were incidentally detected. Ima...

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Main Authors: D. Ippolito, P. Allegranza, P. A. Bonaffini, C. Talei Franzesi, F. Leone, S. Sironi
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2015/707546
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author D. Ippolito
P. Allegranza
P. A. Bonaffini
C. Talei Franzesi
F. Leone
S. Sironi
author_facet D. Ippolito
P. Allegranza
P. A. Bonaffini
C. Talei Franzesi
F. Leone
S. Sironi
author_sort D. Ippolito
collection DOAJ
description Purpose. To assess the diagnostic value of 256-detector row MDCT in the characterization of incidentally detected pancreatic cystic lesions (PCLs). Materials and Methods. We retrospectively reviewed 6389 studies performed on a 256-row detector scanner, wherein ≥1 PCLs were incidentally detected. Images from a total of 192 patients (99 females; age range 31–90 years) were analysed referring to morphologic predictive signs of malignancy, including multifocality, inner septa, wall thickening, and mural enhancing nodules. Results. We evaluated 292 PCLs in 192 patients (solitary in 145 and ≥2 in 47; incidence 2.05%). Size ranged from 3 to 145 mm (mean 15 mm); body was the most common location (87/292; 29.8%). Intralesional septa were detected in 52/292 lesions (17.8%), wall thickening >2 mm in 13 (4.5%), enhancing wall and mural nodules in 15 (5.1%) and 12 (4.1%), respectively. Communication with ductal system was evident in 45 cases. The most common diagnoses, established by histology or imaging analysis, were IPMNs (about 86%), while serous cystic neoplasia (3.7%) and metastases (0.5%) were the less common. Conclusion. MDCT provides detailed features for characterization of PCLs, which are incidentally discovered with increased frequency due to the widespread use of cross-sectional imaging.
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spelling doaj-art-55589a4718ea4b1485b8ab8ca202a79d2025-02-03T01:22:39ZengWileyGastroenterology Research and Practice1687-61211687-630X2015-01-01201510.1155/2015/707546707546Diagnostic Accuracy of 256-Detector Row Computed Tomography in Detection and Characterization of Incidental Pancreatic Cystic LesionsD. Ippolito0P. Allegranza1P. A. Bonaffini2C. Talei Franzesi3F. Leone4S. Sironi5Department of Diagnostic Radiology, School of Medicine, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, School of Medicine, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, School of Medicine, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, School of Medicine, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, School of Medicine, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, School of Medicine, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, ItalyPurpose. To assess the diagnostic value of 256-detector row MDCT in the characterization of incidentally detected pancreatic cystic lesions (PCLs). Materials and Methods. We retrospectively reviewed 6389 studies performed on a 256-row detector scanner, wherein ≥1 PCLs were incidentally detected. Images from a total of 192 patients (99 females; age range 31–90 years) were analysed referring to morphologic predictive signs of malignancy, including multifocality, inner septa, wall thickening, and mural enhancing nodules. Results. We evaluated 292 PCLs in 192 patients (solitary in 145 and ≥2 in 47; incidence 2.05%). Size ranged from 3 to 145 mm (mean 15 mm); body was the most common location (87/292; 29.8%). Intralesional septa were detected in 52/292 lesions (17.8%), wall thickening >2 mm in 13 (4.5%), enhancing wall and mural nodules in 15 (5.1%) and 12 (4.1%), respectively. Communication with ductal system was evident in 45 cases. The most common diagnoses, established by histology or imaging analysis, were IPMNs (about 86%), while serous cystic neoplasia (3.7%) and metastases (0.5%) were the less common. Conclusion. MDCT provides detailed features for characterization of PCLs, which are incidentally discovered with increased frequency due to the widespread use of cross-sectional imaging.http://dx.doi.org/10.1155/2015/707546
spellingShingle D. Ippolito
P. Allegranza
P. A. Bonaffini
C. Talei Franzesi
F. Leone
S. Sironi
Diagnostic Accuracy of 256-Detector Row Computed Tomography in Detection and Characterization of Incidental Pancreatic Cystic Lesions
Gastroenterology Research and Practice
title Diagnostic Accuracy of 256-Detector Row Computed Tomography in Detection and Characterization of Incidental Pancreatic Cystic Lesions
title_full Diagnostic Accuracy of 256-Detector Row Computed Tomography in Detection and Characterization of Incidental Pancreatic Cystic Lesions
title_fullStr Diagnostic Accuracy of 256-Detector Row Computed Tomography in Detection and Characterization of Incidental Pancreatic Cystic Lesions
title_full_unstemmed Diagnostic Accuracy of 256-Detector Row Computed Tomography in Detection and Characterization of Incidental Pancreatic Cystic Lesions
title_short Diagnostic Accuracy of 256-Detector Row Computed Tomography in Detection and Characterization of Incidental Pancreatic Cystic Lesions
title_sort diagnostic accuracy of 256 detector row computed tomography in detection and characterization of incidental pancreatic cystic lesions
url http://dx.doi.org/10.1155/2015/707546
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