Cardiopulmonary Arrest and Pulmonary Hypertension in an Infant with Pertussis Case Report

Pertussis is a vaccine-preventable disease with an incidence that has been trending upwards in the United States over the last two decades. This is evident by an increase in the incidence from 10,100 cases in 1974 to a peak of >48,000 cases noted in the last decade. Pertussis disease severity ran...

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Main Authors: Patrick Ovie Fueta, Harry Onoriode Eyituoyo, Oghogho Igbinoba, Jon Roberts
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2021/6686185
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author Patrick Ovie Fueta
Harry Onoriode Eyituoyo
Oghogho Igbinoba
Jon Roberts
author_facet Patrick Ovie Fueta
Harry Onoriode Eyituoyo
Oghogho Igbinoba
Jon Roberts
author_sort Patrick Ovie Fueta
collection DOAJ
description Pertussis is a vaccine-preventable disease with an incidence that has been trending upwards in the United States over the last two decades. This is evident by an increase in the incidence from 10,100 cases in 1974 to a peak of >48,000 cases noted in the last decade. Pertussis disease severity ranges from mild to severe, with resultant complications capable of causing significant morbidity and mortality. We report a case of pertussis in a 5-week-old female infant who presented with fever, paroxysms of cough, apnea, and seizures leading to cardiopulmonary arrest. Cardiopulmonary resuscitation lasted 11 minutes before the return of spontaneous circulation. She was transferred to our tertiary facility and admitted to the pediatric intensive care unit. Complete blood count revealed significant leukocytosis, chest X-ray revealed bilateral pulmonary edema with pleural effusion, and echocardiogram demonstrated pulmonary hypertension. Bordetella pertussis infection was confirmed on respiratory polymerase chain reaction. She was treated with antibiotics, ventilatory management, and other supportive care. She was discharged on room air after a hospital course of 7 weeks with care coordination between her primary care provider, pulmonologist, and neurologist. Despite the positive outcome in this case, it is important to note that managing severe pertussis involves multidisciplinary care, and the morbidity and cost implications can be mitigated on a population scale through vaccine optimization strategies.
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spelling doaj-art-5556bbc8e85d443e98c746c647dcfbc22025-02-03T01:09:56ZengWileyCase Reports in Infectious Diseases2090-66252090-66332021-01-01202110.1155/2021/66861856686185Cardiopulmonary Arrest and Pulmonary Hypertension in an Infant with Pertussis Case ReportPatrick Ovie Fueta0Harry Onoriode Eyituoyo1Oghogho Igbinoba2Jon Roberts3Driscoll Children’s Hospital, Corpus Christi, TX, USAMercer University School of Medicine, Macon, GA, USADriscoll Children’s Hospital, Corpus Christi, TX, USADriscoll Children’s Hospital, Corpus Christi, TX, USAPertussis is a vaccine-preventable disease with an incidence that has been trending upwards in the United States over the last two decades. This is evident by an increase in the incidence from 10,100 cases in 1974 to a peak of >48,000 cases noted in the last decade. Pertussis disease severity ranges from mild to severe, with resultant complications capable of causing significant morbidity and mortality. We report a case of pertussis in a 5-week-old female infant who presented with fever, paroxysms of cough, apnea, and seizures leading to cardiopulmonary arrest. Cardiopulmonary resuscitation lasted 11 minutes before the return of spontaneous circulation. She was transferred to our tertiary facility and admitted to the pediatric intensive care unit. Complete blood count revealed significant leukocytosis, chest X-ray revealed bilateral pulmonary edema with pleural effusion, and echocardiogram demonstrated pulmonary hypertension. Bordetella pertussis infection was confirmed on respiratory polymerase chain reaction. She was treated with antibiotics, ventilatory management, and other supportive care. She was discharged on room air after a hospital course of 7 weeks with care coordination between her primary care provider, pulmonologist, and neurologist. Despite the positive outcome in this case, it is important to note that managing severe pertussis involves multidisciplinary care, and the morbidity and cost implications can be mitigated on a population scale through vaccine optimization strategies.http://dx.doi.org/10.1155/2021/6686185
spellingShingle Patrick Ovie Fueta
Harry Onoriode Eyituoyo
Oghogho Igbinoba
Jon Roberts
Cardiopulmonary Arrest and Pulmonary Hypertension in an Infant with Pertussis Case Report
Case Reports in Infectious Diseases
title Cardiopulmonary Arrest and Pulmonary Hypertension in an Infant with Pertussis Case Report
title_full Cardiopulmonary Arrest and Pulmonary Hypertension in an Infant with Pertussis Case Report
title_fullStr Cardiopulmonary Arrest and Pulmonary Hypertension in an Infant with Pertussis Case Report
title_full_unstemmed Cardiopulmonary Arrest and Pulmonary Hypertension in an Infant with Pertussis Case Report
title_short Cardiopulmonary Arrest and Pulmonary Hypertension in an Infant with Pertussis Case Report
title_sort cardiopulmonary arrest and pulmonary hypertension in an infant with pertussis case report
url http://dx.doi.org/10.1155/2021/6686185
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