Salivary miRNAs and cytokines associated with diagnosis and prognosis of oral squamous cell carcinoma
Oral squamous cell carcinoma (OSCC) is the most common malignant tumour in the oral and maxillofacial region. Early diagnosis can significantly improve the 5-year survival rate of patients with OSCC. Therefore, it is extremely important to differentiate OSCC patients early, easily and quickly. Human...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Cell and Developmental Biology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2025.1531016/full |
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| author | Yuxiao Qin Xiaodan Dong Bo Li |
| author_facet | Yuxiao Qin Xiaodan Dong Bo Li |
| author_sort | Yuxiao Qin |
| collection | DOAJ |
| description | Oral squamous cell carcinoma (OSCC) is the most common malignant tumour in the oral and maxillofacial region. Early diagnosis can significantly improve the 5-year survival rate of patients with OSCC. Therefore, it is extremely important to differentiate OSCC patients early, easily and quickly. Human saliva contains a variety of components that can be used as biomarkers for the diagnosis and prognosis of OSCC. Studies have shown that salivary microRNAs (miRNAs) and cytokines are closely associated with the progression of OSCC. The aim of this review is to summarize the research progress of salivary biomarkers (miRNAs and cytokines) in the past 3 years, and to explore the possibility of using miRNAs and cytokines to improve the diagnosis and prognosis of OSCC. |
| format | Article |
| id | doaj-art-55495065b25c467fbb0e6cc072bcc702 |
| institution | Kabale University |
| issn | 2296-634X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj-art-55495065b25c467fbb0e6cc072bcc7022025-01-22T07:14:54ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2025-01-011310.3389/fcell.2025.15310161531016Salivary miRNAs and cytokines associated with diagnosis and prognosis of oral squamous cell carcinomaYuxiao QinXiaodan DongBo LiOral squamous cell carcinoma (OSCC) is the most common malignant tumour in the oral and maxillofacial region. Early diagnosis can significantly improve the 5-year survival rate of patients with OSCC. Therefore, it is extremely important to differentiate OSCC patients early, easily and quickly. Human saliva contains a variety of components that can be used as biomarkers for the diagnosis and prognosis of OSCC. Studies have shown that salivary microRNAs (miRNAs) and cytokines are closely associated with the progression of OSCC. The aim of this review is to summarize the research progress of salivary biomarkers (miRNAs and cytokines) in the past 3 years, and to explore the possibility of using miRNAs and cytokines to improve the diagnosis and prognosis of OSCC.https://www.frontiersin.org/articles/10.3389/fcell.2025.1531016/fulloral squamous cell carcinomadiagnosis and prognosissalivary biomarkermiRNAscytokines |
| spellingShingle | Yuxiao Qin Xiaodan Dong Bo Li Salivary miRNAs and cytokines associated with diagnosis and prognosis of oral squamous cell carcinoma Frontiers in Cell and Developmental Biology oral squamous cell carcinoma diagnosis and prognosis salivary biomarker miRNAs cytokines |
| title | Salivary miRNAs and cytokines associated with diagnosis and prognosis of oral squamous cell carcinoma |
| title_full | Salivary miRNAs and cytokines associated with diagnosis and prognosis of oral squamous cell carcinoma |
| title_fullStr | Salivary miRNAs and cytokines associated with diagnosis and prognosis of oral squamous cell carcinoma |
| title_full_unstemmed | Salivary miRNAs and cytokines associated with diagnosis and prognosis of oral squamous cell carcinoma |
| title_short | Salivary miRNAs and cytokines associated with diagnosis and prognosis of oral squamous cell carcinoma |
| title_sort | salivary mirnas and cytokines associated with diagnosis and prognosis of oral squamous cell carcinoma |
| topic | oral squamous cell carcinoma diagnosis and prognosis salivary biomarker miRNAs cytokines |
| url | https://www.frontiersin.org/articles/10.3389/fcell.2025.1531016/full |
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