Live Birth from the Transfer of a Severely Fragmented Embryo Observed by Morphokinetics
We report a live birth from a heavily fragmented embryo which continued cleavage to a fully expanded blastocyst. A 32-year-old patient underwent 2 IVF cycles without achieving pregnancy. In the first cycle, 2 embryos with fragmentation were transferred; in the second, all embryos were fragmented and...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2018/2152918 |
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| author | S. Lahav-Baratz I. Blais M. Koifman D. Ishai Z. Wiener-Megnazi G. Peer M. Dirnfeld |
| author_facet | S. Lahav-Baratz I. Blais M. Koifman D. Ishai Z. Wiener-Megnazi G. Peer M. Dirnfeld |
| author_sort | S. Lahav-Baratz |
| collection | DOAJ |
| description | We report a live birth from a heavily fragmented embryo which continued cleavage to a fully expanded blastocyst. A 32-year-old patient underwent 2 IVF cycles without achieving pregnancy. In the first cycle, 2 embryos with fragmentation were transferred; in the second, all embryos were fragmented and no embryo transfer was performed. In a third cycle, 12 oocytes were retrieved and 11 of them were fertilized. On day 2, all 11 embryos started to unwind to fragments. By careful annotation, using the time-lapse EmbryoScope, we observed that one embryo continued division as expected, discarding all fragments aside. On day 5, this embryo showed promising annotation according to our lab model. The embryo was transferred into the uterus and resulted in the birth of a healthy baby at term. To our knowledge, this is the first case report assisted by EmbryoScope where a healthy baby was delivered from a fragmented embryo. |
| format | Article |
| id | doaj-art-55419e16583447eea95aecf41cc703c9 |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-55419e16583447eea95aecf41cc703c92025-02-03T06:13:58ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922018-01-01201810.1155/2018/21529182152918Live Birth from the Transfer of a Severely Fragmented Embryo Observed by MorphokineticsS. Lahav-Baratz0I. Blais1M. Koifman2D. Ishai3Z. Wiener-Megnazi4G. Peer5M. Dirnfeld6Obs/Gyn Department IVF Unit, Lady Davis Carmel Medical Center, Haifa, IsraelObs/Gyn Department IVF Unit, Lady Davis Carmel Medical Center, Haifa, IsraelObs/Gyn Department IVF Unit, Lady Davis Carmel Medical Center, Haifa, IsraelObs/Gyn Department IVF Unit, Lady Davis Carmel Medical Center, Haifa, IsraelObs/Gyn Department IVF Unit, Lady Davis Carmel Medical Center, Haifa, IsraelObs/Gyn Department IVF Unit, Lady Davis Carmel Medical Center, Haifa, IsraelObs/Gyn Department IVF Unit, Lady Davis Carmel Medical Center, Haifa, IsraelWe report a live birth from a heavily fragmented embryo which continued cleavage to a fully expanded blastocyst. A 32-year-old patient underwent 2 IVF cycles without achieving pregnancy. In the first cycle, 2 embryos with fragmentation were transferred; in the second, all embryos were fragmented and no embryo transfer was performed. In a third cycle, 12 oocytes were retrieved and 11 of them were fertilized. On day 2, all 11 embryos started to unwind to fragments. By careful annotation, using the time-lapse EmbryoScope, we observed that one embryo continued division as expected, discarding all fragments aside. On day 5, this embryo showed promising annotation according to our lab model. The embryo was transferred into the uterus and resulted in the birth of a healthy baby at term. To our knowledge, this is the first case report assisted by EmbryoScope where a healthy baby was delivered from a fragmented embryo.http://dx.doi.org/10.1155/2018/2152918 |
| spellingShingle | S. Lahav-Baratz I. Blais M. Koifman D. Ishai Z. Wiener-Megnazi G. Peer M. Dirnfeld Live Birth from the Transfer of a Severely Fragmented Embryo Observed by Morphokinetics Case Reports in Obstetrics and Gynecology |
| title | Live Birth from the Transfer of a Severely Fragmented Embryo Observed by Morphokinetics |
| title_full | Live Birth from the Transfer of a Severely Fragmented Embryo Observed by Morphokinetics |
| title_fullStr | Live Birth from the Transfer of a Severely Fragmented Embryo Observed by Morphokinetics |
| title_full_unstemmed | Live Birth from the Transfer of a Severely Fragmented Embryo Observed by Morphokinetics |
| title_short | Live Birth from the Transfer of a Severely Fragmented Embryo Observed by Morphokinetics |
| title_sort | live birth from the transfer of a severely fragmented embryo observed by morphokinetics |
| url | http://dx.doi.org/10.1155/2018/2152918 |
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