Conjugation of Daunorubicin to Monoclonal Antihuman Sarcoma Antibody by a Novel Method
Most of the reported methods for coupling anthracycline drugs to antibody result in either a loss of pharmacological activity or yield antibodies which have lost much of their immunological specificity. The use of glutaraldehyde for coupling saves both the pharmacological and immunological activitie...
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Main Authors: | Michel Pagé, Denis Thibeault, Hélène Tremblay, Christiane Noël, Marie-Josée Perron |
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Format: | Article |
Language: | English |
Published: |
Wiley
1992-01-01
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Series: | Canadian Journal of Infectious Diseases |
Online Access: | http://dx.doi.org/10.1155/1992/398178 |
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