Case Report: Severe acute pancreatitis accompanied by gastric mucosal exfoliation hemorrhage: clinical alerts and novel insights
Acute pancreatitis (AP), a condition marked by its swift progression, substantial individual discrepancies, and profound concealment, poses a formidable challenge. Within its severe form, known as severe acute pancreatitis (SAP), the disease assumes an even more prevalent status, often entwined with...
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| Format: | Article |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2024.1471966/full |
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| author | Yanquan Liu Hehui Zhang Minjuan Zeng Jian Luo Yun Lai He Huang Qinglin Xu Yuan Liu |
| author_facet | Yanquan Liu Hehui Zhang Minjuan Zeng Jian Luo Yun Lai He Huang Qinglin Xu Yuan Liu |
| author_sort | Yanquan Liu |
| collection | DOAJ |
| description | Acute pancreatitis (AP), a condition marked by its swift progression, substantial individual discrepancies, and profound concealment, poses a formidable challenge. Within its severe form, known as severe acute pancreatitis (SAP), the disease assumes an even more prevalent status, often entwined with dire complications such as pancreatic abscess, circulatory shock, and the direst of all, multiple organ failure. Regrettably, the conjunction of SAP with gastric mucosal exfoliation culminating in massive hemorrhage remains an exceptionally rare phenomenon within the clinical realm. This study delves into a retrospective analysis of a singular, yet remarkable clinical case, where SAP's therapeutic odyssey unexpectedly led to gastric mucosa stripping and catastrophic gastrointestinal bleeding. This paper endeavors to unravel the diagnostic intricacies, explore the treatment modalities, and prognosticate the outcome, all with the ultimate aim of fostering a heightened clinical vigilance and fostering a novel, nuanced understanding of SAP's exceptional complications within the intensive care arena. Furthermore, this study aspires to serve as a beacon of reference, illuminating the path for clinical practitioners confronted with such elusive yet critical scenarios. |
| format | Article |
| id | doaj-art-54e0b5e6f50f400580db68bf5eee5153 |
| institution | Kabale University |
| issn | 2296-875X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj-art-54e0b5e6f50f400580db68bf5eee51532025-01-28T13:59:38ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2025-01-011110.3389/fsurg.2024.14719661471966Case Report: Severe acute pancreatitis accompanied by gastric mucosal exfoliation hemorrhage: clinical alerts and novel insightsYanquan Liu0Hehui Zhang1Minjuan Zeng2Jian Luo3Yun Lai4He Huang5Qinglin Xu6Yuan Liu7The First School of Clinical Medicine, Guangdong Medical University, Guangdong, ChinaDepartment of Intensive Medicine (Comprehensive ICU), The First Affiliated Hospital of Gannan Medical University, Ganzhou, ChinaThe First School of Clinical Medicine, Guangdong Medical University, Guangdong, ChinaDepartment of Gastroenterology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, ChinaDepartment of Dermatology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, ChinaDepartment of Cardiovascular Medicine (Cardiology), The First Affiliated Hospital of Gannan Medical University, Ganzhou, ChinaDepartment of Intensive Medicine (Comprehensive ICU), The First Affiliated Hospital of Gannan Medical University, Ganzhou, ChinaDepartment of Operating Room, The First Affiliated Hospital of Gannan Medical University, Ganzhou, ChinaAcute pancreatitis (AP), a condition marked by its swift progression, substantial individual discrepancies, and profound concealment, poses a formidable challenge. Within its severe form, known as severe acute pancreatitis (SAP), the disease assumes an even more prevalent status, often entwined with dire complications such as pancreatic abscess, circulatory shock, and the direst of all, multiple organ failure. Regrettably, the conjunction of SAP with gastric mucosal exfoliation culminating in massive hemorrhage remains an exceptionally rare phenomenon within the clinical realm. This study delves into a retrospective analysis of a singular, yet remarkable clinical case, where SAP's therapeutic odyssey unexpectedly led to gastric mucosa stripping and catastrophic gastrointestinal bleeding. This paper endeavors to unravel the diagnostic intricacies, explore the treatment modalities, and prognosticate the outcome, all with the ultimate aim of fostering a heightened clinical vigilance and fostering a novel, nuanced understanding of SAP's exceptional complications within the intensive care arena. Furthermore, this study aspires to serve as a beacon of reference, illuminating the path for clinical practitioners confronted with such elusive yet critical scenarios.https://www.frontiersin.org/articles/10.3389/fsurg.2024.1471966/fullsevere acute pancreatitis (SAP)gastric mucosal exfoliation hemorrhagedifferential diagnosistreatmentprognosis |
| spellingShingle | Yanquan Liu Hehui Zhang Minjuan Zeng Jian Luo Yun Lai He Huang Qinglin Xu Yuan Liu Case Report: Severe acute pancreatitis accompanied by gastric mucosal exfoliation hemorrhage: clinical alerts and novel insights Frontiers in Surgery severe acute pancreatitis (SAP) gastric mucosal exfoliation hemorrhage differential diagnosis treatment prognosis |
| title | Case Report: Severe acute pancreatitis accompanied by gastric mucosal exfoliation hemorrhage: clinical alerts and novel insights |
| title_full | Case Report: Severe acute pancreatitis accompanied by gastric mucosal exfoliation hemorrhage: clinical alerts and novel insights |
| title_fullStr | Case Report: Severe acute pancreatitis accompanied by gastric mucosal exfoliation hemorrhage: clinical alerts and novel insights |
| title_full_unstemmed | Case Report: Severe acute pancreatitis accompanied by gastric mucosal exfoliation hemorrhage: clinical alerts and novel insights |
| title_short | Case Report: Severe acute pancreatitis accompanied by gastric mucosal exfoliation hemorrhage: clinical alerts and novel insights |
| title_sort | case report severe acute pancreatitis accompanied by gastric mucosal exfoliation hemorrhage clinical alerts and novel insights |
| topic | severe acute pancreatitis (SAP) gastric mucosal exfoliation hemorrhage differential diagnosis treatment prognosis |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2024.1471966/full |
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