Ethnic differences between South Asians and white Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review protocol

Introduction Cardiovascular disease (CVD) is the leading cause of death worldwide, with significantly worse CVD outcomes in ethnic minorities in developed countries, especially South Asians, compared with the prevailing white ethnic group. This protocol outlines the process for conducting a systemat...

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Main Authors: Olalekan Abdulrahman Uthman, Mubarak Patel, Salim Abatcha
Format: Article
Language:English
Published: BMJ Publishing Group 2022-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/7/e052487.full
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author Olalekan Abdulrahman Uthman
Mubarak Patel
Salim Abatcha
author_facet Olalekan Abdulrahman Uthman
Mubarak Patel
Salim Abatcha
author_sort Olalekan Abdulrahman Uthman
collection DOAJ
description Introduction Cardiovascular disease (CVD) is the leading cause of death worldwide, with significantly worse CVD outcomes in ethnic minorities in developed countries, especially South Asians, compared with the prevailing white ethnic group. This protocol outlines the process for conducting a systematic literature review to investigate the CVD outcome inequalities between South Asian and white Caucasian ethnic groups.Methods Studies that compared the South Asian ethnic minority with the predominant white ethnicity in developed countries with CVD will be included from inception to 22 April 2021. We will search MEDLINE, Embase, Web of Science and grey literature to find all relevant peer-reviewed articles, reports and online theses. Articles will be screened using inclusion/exclusion criteria applied first at the title and abstract level, and then full texts, both by two independent reviewers. Articles kept in the review will undergo a risk of bias assessment using the Quality In Prognosis Studies tool and data will be extracted. Random-effects meta-analysis and heterogeneity tests will be undertaken, and tests for publication bias, outlying highly-influential observations. If insufficient data is founded or studies are highly heterogeneous, a narrative synthesis will be conducted.Ethics Formal ethical approval is not required for this review.Dissemination The results and findings of this systematic literature review will be disseminated through peer-reviewed publications and reports.PROSPERO registration number CRD42021240865.
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spelling doaj-art-54d79016ea04408baf82f19a2eba83c62025-01-31T10:20:10ZengBMJ Publishing GroupBMJ Open2044-60552022-07-0112710.1136/bmjopen-2021-052487Ethnic differences between South Asians and white Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review protocolOlalekan Abdulrahman Uthman0Mubarak Patel1Salim Abatcha2Warwick Medical School, University of Warwick, Warwick, Coventry, UKWarwick Evidence, Warwick Medical School, University of Warwick, Coventry, UKWarwick Medical School, University of Warwick, Warwick, Coventry, UKIntroduction Cardiovascular disease (CVD) is the leading cause of death worldwide, with significantly worse CVD outcomes in ethnic minorities in developed countries, especially South Asians, compared with the prevailing white ethnic group. This protocol outlines the process for conducting a systematic literature review to investigate the CVD outcome inequalities between South Asian and white Caucasian ethnic groups.Methods Studies that compared the South Asian ethnic minority with the predominant white ethnicity in developed countries with CVD will be included from inception to 22 April 2021. We will search MEDLINE, Embase, Web of Science and grey literature to find all relevant peer-reviewed articles, reports and online theses. Articles will be screened using inclusion/exclusion criteria applied first at the title and abstract level, and then full texts, both by two independent reviewers. Articles kept in the review will undergo a risk of bias assessment using the Quality In Prognosis Studies tool and data will be extracted. Random-effects meta-analysis and heterogeneity tests will be undertaken, and tests for publication bias, outlying highly-influential observations. If insufficient data is founded or studies are highly heterogeneous, a narrative synthesis will be conducted.Ethics Formal ethical approval is not required for this review.Dissemination The results and findings of this systematic literature review will be disseminated through peer-reviewed publications and reports.PROSPERO registration number CRD42021240865.https://bmjopen.bmj.com/content/12/7/e052487.full
spellingShingle Olalekan Abdulrahman Uthman
Mubarak Patel
Salim Abatcha
Ethnic differences between South Asians and white Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review protocol
BMJ Open
title Ethnic differences between South Asians and white Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review protocol
title_full Ethnic differences between South Asians and white Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review protocol
title_fullStr Ethnic differences between South Asians and white Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review protocol
title_full_unstemmed Ethnic differences between South Asians and white Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review protocol
title_short Ethnic differences between South Asians and white Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review protocol
title_sort ethnic differences between south asians and white caucasians in cardiovascular disease related mortality in developed countries a systematic literature review protocol
url https://bmjopen.bmj.com/content/12/7/e052487.full
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