Therapeutic Effects of GDF6-Overexpressing Mesenchymal Stem Cells through Upregulation of the GDF15/SIRT1 Axis in Age-Related Hearing Loss

Therapeutic Effects of GDF6-Overexpressing Mesenchymal Stem Cells through Upregulation of the GDF15/SIRT1 Axis in Age-Related Hearing Loss

Background: It has been reported the therapeutic effects of mesenchymal stem cells (MSCs) on hearing loss. This study explored the therapeutic effects of growth differentiation factor 6 (GDF6) overexpression-induced MSCs (MSCs-GDF6) on age-related hearing loss (ARHL) and its under...

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Bibliographic Details
Main Authors: Jiali Liu, Haisen Peng, Yuehui Liu, Chunhua Li, Wen Xie
Format: Article
Language:English
Published: IMR Press 2025-01-01
Series:Frontiers in Bioscience-Landmark
Subjects:
mesenchymal stem cells
gdf15
sirt1
cochlear hair cell
age-related hearing loss
Online Access:https://www.imrpress.com/journal/FBL/30/1/10.31083/FBL26179
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