Efficacy of Aloe vera, Ananas comosus, and Sansevieria masoniana Cream on the Skin Wound Infected with MRSA
The tropical area has a lot of herbal medicines such as Aloe vera (AV), Ananas comosus (AC), and Sansevieria masoniana (SM). All the three have a unique potential effect as an antibacterial and wound-healing promoter. The aim of this study is to explore the role of AV, AC, and SM on the skin wound i...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Advances in Pharmacological Sciences |
| Online Access: | http://dx.doi.org/10.1155/2018/4670569 |
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| author | Yos Adi Prakoso Chylen Setiyo Rini Roeswandono Wirjaatmadja |
| author_facet | Yos Adi Prakoso Chylen Setiyo Rini Roeswandono Wirjaatmadja |
| author_sort | Yos Adi Prakoso |
| collection | DOAJ |
| description | The tropical area has a lot of herbal medicines such as Aloe vera (AV), Ananas comosus (AC), and Sansevieria masoniana (SM). All the three have a unique potential effect as an antibacterial and wound-healing promoter. The aim of this study is to explore the role of AV, AC, and SM on the skin wound infected with methicillin-resistant Staphylococcus aureus (MRSA). Forty-five adult female Sprague Dawley rats weighing 250–300 grams were divided into 5 groups. All the groups were exposed to two round full-thickness punch biopsy and infected with MRSA. The group C was the control group/untreated; group BC was treated with base cream/without extract; group AV was treated with 75% AV cream; group AC was treated with 75% AC cream, and group SM was treated with 75% SM cream. The wounds were observed on days 5, 10, and 15. The healing of skin wounds was measured by a percentage of closure, skin tensile strength, and histopathology. The result showed that AV, AC, and SM have a similar potential effect on healing in the wound that was infected with MRSA compared to the groups C and BC (P<0.05). It shows that all the three herbal formulations can be used as the alternative therapy to the wound infected with MRSA. |
| format | Article |
| id | doaj-art-54c5c37caf5d4472a7cebf6e5ef76426 |
| institution | Kabale University |
| issn | 1687-6334 1687-6342 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Pharmacological Sciences |
| spelling | doaj-art-54c5c37caf5d4472a7cebf6e5ef764262025-02-03T01:10:54ZengWileyAdvances in Pharmacological Sciences1687-63341687-63422018-01-01201810.1155/2018/46705694670569Efficacy of Aloe vera, Ananas comosus, and Sansevieria masoniana Cream on the Skin Wound Infected with MRSAYos Adi Prakoso0Chylen Setiyo Rini1Roeswandono Wirjaatmadja2Integrated Laboratory, Faculty of Health, University of Muhammadiyah Sidoarjo, East Java, IndonesiaIntegrated Laboratory, Faculty of Health, University of Muhammadiyah Sidoarjo, East Java, IndonesiaFaculty of Veterinary Medicine, University of Wijaya Kusuma Surabaya, East Java, IndonesiaThe tropical area has a lot of herbal medicines such as Aloe vera (AV), Ananas comosus (AC), and Sansevieria masoniana (SM). All the three have a unique potential effect as an antibacterial and wound-healing promoter. The aim of this study is to explore the role of AV, AC, and SM on the skin wound infected with methicillin-resistant Staphylococcus aureus (MRSA). Forty-five adult female Sprague Dawley rats weighing 250–300 grams were divided into 5 groups. All the groups were exposed to two round full-thickness punch biopsy and infected with MRSA. The group C was the control group/untreated; group BC was treated with base cream/without extract; group AV was treated with 75% AV cream; group AC was treated with 75% AC cream, and group SM was treated with 75% SM cream. The wounds were observed on days 5, 10, and 15. The healing of skin wounds was measured by a percentage of closure, skin tensile strength, and histopathology. The result showed that AV, AC, and SM have a similar potential effect on healing in the wound that was infected with MRSA compared to the groups C and BC (P<0.05). It shows that all the three herbal formulations can be used as the alternative therapy to the wound infected with MRSA.http://dx.doi.org/10.1155/2018/4670569 |
| spellingShingle | Yos Adi Prakoso Chylen Setiyo Rini Roeswandono Wirjaatmadja Efficacy of Aloe vera, Ananas comosus, and Sansevieria masoniana Cream on the Skin Wound Infected with MRSA Advances in Pharmacological Sciences |
| title | Efficacy of Aloe vera, Ananas comosus, and Sansevieria masoniana Cream on the Skin Wound Infected with MRSA |
| title_full | Efficacy of Aloe vera, Ananas comosus, and Sansevieria masoniana Cream on the Skin Wound Infected with MRSA |
| title_fullStr | Efficacy of Aloe vera, Ananas comosus, and Sansevieria masoniana Cream on the Skin Wound Infected with MRSA |
| title_full_unstemmed | Efficacy of Aloe vera, Ananas comosus, and Sansevieria masoniana Cream on the Skin Wound Infected with MRSA |
| title_short | Efficacy of Aloe vera, Ananas comosus, and Sansevieria masoniana Cream on the Skin Wound Infected with MRSA |
| title_sort | efficacy of aloe vera ananas comosus and sansevieria masoniana cream on the skin wound infected with mrsa |
| url | http://dx.doi.org/10.1155/2018/4670569 |
| work_keys_str_mv | AT yosadiprakoso efficacyofaloeveraananascomosusandsansevieriamasonianacreamontheskinwoundinfectedwithmrsa AT chylensetiyorini efficacyofaloeveraananascomosusandsansevieriamasonianacreamontheskinwoundinfectedwithmrsa AT roeswandonowirjaatmadja efficacyofaloeveraananascomosusandsansevieriamasonianacreamontheskinwoundinfectedwithmrsa |