Targeting Epac2 and GluA3-containing AMPARs: a novel therapeutic strategy for Alzheimer’s disease

Targeting Epac2 and GluA3-containing AMPARs: a novel therapeutic strategy for Alzheimer’s disease

Saved in:

Bibliographic Details
Main Authors:	Tong Zhang, Martina Schmidt
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2025-11-01
Series:	Neural Regeneration Research
Online Access:	https://journals.lww.com/10.4103/NRR.NRR-D-24-00751
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

GluA2 palmitoylation by SELENOK modulates AMPAR assembly and synaptic plasticity in Alzheimer's disease
by: Jiaying Peng, et al.
Published: (2025-10-01)

Identification of a novel signaling pathway and its relevance for GluA1 recycling.
by: Guiscard Seebohm, et al.
Published: (2012-01-01)

Cysteine 893 is a target of regulatory thiol modifications of GluA1 AMPA receptors.
by: Lotta von Ossowski, et al.
Published: (2017-01-01)

AMPA GluA1-flip targeted oligonucleotide therapy reduces neonatal seizures and hyperexcitability.
by: Nicole M Lykens, et al.
Published: (2017-01-01)

GluA1 Phosphorylation Alters Evoked Firing Pattern In Vivo
by: Balázs Barkóczi, et al.
Published: (2012-01-01)

The Frmpd3 Protein Regulates Susceptibility to Epilepsy by Combining with GRIP and GluA2
by: Yan Jia, et al.
Published: (2025-03-01)

Effects of Electroacupuncture on Syt3 and GluA2 in Rats With Limb Spasms After Intracerebral Hemorrhage
by: Xudong Lu, et al.
Published: (2025-03-01)

Endophilin2 Interacts with GluA1 to Mediate AMPA Receptor Endocytosis Induced by Oligomeric Amyloid-β
by: Jifeng Zhang, et al.
Published: (2017-01-01)

Terahertz Wave Alleviates Comorbidity Anxiety in Pain by Reducing the Binding Capacity of Nanostructured Glutamate Molecules to GluA2
by: Zihua Song, et al.
Published: (2024-01-01)

Multiplex CRISPR/Cas9 Editing of Rice Prolamin and GluA Glutelin Genes Reveals Subfamily-Specific Effects on Seed Protein Composition
by: María H. Guzmán-López, et al.
Published: (2025-07-01)

Elevated Autoantibodies to the GluA1 Subunit of the AMPA Receptor in Blood Indicate Risk of Cognitive Impairment in Contact Sports Athletes, Irrespective of Concussion
by: Christopher Bailey, et al.
Published: (2024-11-01)

The GluN3-containing NMDA receptors
by: Kunlong Xiong, et al.
Published: (2025-12-01)

Corticosterone alters AMPAR mobility and facilitates bidirectional synaptic plasticity.
by: Stéphane Martin, et al.
Published: (2009-01-01)

Targeting endothelial junctional adhesion molecule‐A/ EPAC/ Rap‐1 axis as a novel strategy to increase stem cell engraftment in dystrophic muscles
by: Monica Giannotta, et al.
Published: (2013-12-01)

The cardiotropic properties of ZMEI-3 compound – a potential inhibitor of Epac proteins
by: S. A. Kryzhanovskii, et al.
Published: (2025-01-01)

Flexible electromagnetic radiation shields based on carbon-containing glued compounds
by: E. S. Belousova, et al.
Published: (2019-06-01)

Activation of neurogenesis in the hippocampus is a novel therapeutic target for Alzheimer's disease
by: Akihiko Taguchi, et al.
Published: (2023-12-01)

Clinical characteristics and outcome in patients with anti-AMPAR2 encephalitis: a case series and literature review
by: Congcong Wang, et al.
Published: (2025-07-01)

Selective EPAC1 activators enhance endothelial function in models of vascular inflammation
by: Neil MacRitchie, et al.
Published: (2025-10-01)

Gluing the Glued Patch: A Glue in Time Saves it all
by: Rinky Agarwal, et al.
Published: (2020-10-01)

Inhibition of EPAC1 signaling pathway alters atrial electrophysiology and prevents atrial fibrillation
by: Bastien Guillot, et al.
Published: (2023-02-01)

Role of p120 Catenin in Epac1-Induced Chronic Postsurgical Pain in Rats
by: Peng Pan, et al.
Published: (2019-01-01)

Beta-hydroxybutyrate counteracts the deleterious effects of a saturated high-fat diet on synaptic AMPAR receptors and cognitive performance
by: Rocío Rojas, et al.
Published: (2025-09-01)

Valuasi Ekonomi Ekosistem Mangrove Berbasis Ekowisata pada Hutan Desa di Kecamatan Batu Ampar Kalimantan Barat
by: Abdul Jabbar, et al.
Published: (2021-04-01)

Microglial Transient Receptor Potential Melastatin 2 Deficiency Accelerates Seizure Development via Increasing AMPAR‐Mediated Neuronal Excitability
by: Yingwei Xu, et al.
Published: (2025-08-01)

Correction: Inhibition of EPAC1 signaling pathway alters atrial electrophysiology and prevents atrial fibrillation
by: Bastien Guillot, et al.
Published: (2025-08-01)

Epac signaling protein ligands as tools for studying their biological activity and creating new original drugs
by: G. V. Mokrov, et al.
Published: (2020-04-01)

Erratum to “Epac1 Restores Normal Insulin Signaling through a Reduction in Inflammatory Cytokines”
by: Elizabeth Curtiss, et al.
Published: (2019-01-01)

CAV-1 Overexpression Exacerbates the Manifestation in EPAC-1-Induced Chronic Postsurgical Pain in Rats
by: Qian Hua, et al.
Published: (2022-01-01)

The Impact of <i>EPAC2</i>-Associated Junction Plakoglobin on Respiratory Syncytial Virus Infection
by: Chaitra A. Takle, et al.
Published: (2025-04-01)

A Novel Technique in Fibrin Gluing of Intercostal Nerves: Splint and Weld
by: Prem Singh Bhandari
Published: (2020-08-01)

Ensuring that toponium is glued, not nailed
by: Felipe J. Llanes-Estrada
Published: (2025-07-01)

Electrophysiological remodelling in human atrial cardiomyocyte: role of Exchange Proteins directly Activated by cAMP (EPAC)
by: Arthur Boileve, et al.
Published: (2024-11-01)

Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway
by: Bo Yao, et al.
Published: (2024-11-01)

DDL-920 mediated enhancement of γ-oscillations targeting γ-aminobutyric acid receptors: a novel therapeutic strategy to improve cognition in Alzheimer's disease
by: Ali Aamir, et al.
Published: (2025-03-01)

Editorial: Alzheimer's disease: new insights into biomechanisms and therapeutic target
by: Yang Zhang, et al.
Published: (2025-03-01)

Myeloperoxidase as a therapeutic target for oxidative damage in Alzheimer’s disease
by: Astrid Mayleth Rivera Antonio, et al.
Published: (2025-12-01)

The Influence of Empowerment and Transformational Leadership on Member Welfare with Farmers Group Performance as a Mediation Variable (Case Study in Ampar Adhum Farmers Group)
by: Muhammad Faqih As Shiddieq, et al.
Published: (2025-01-01)

Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment
by: Jaume Folch, et al.
Published: (2016-01-01)

Epac1 increases myosin regulatory light-chain phosphorylation, energetic cost of contraction, and susceptibility to heart failure.
by: Yoshiki Ohnuki, et al.
Published: (2025-01-01)