Exploring the anti-tumor mechanisms of thiourea-derived CXCR2 antagonists: a computational perspective
Abstract Cancer stands as one of the most difficult health challenges, posing significant dangers due to its ability to proliferate uncontrollably and spread throughout the body. CXCR2 is a G-protein coupled receptor that has significant interference in tumor development and metastasis. Its overexpr...
Saved in:
| Main Authors: | Khadija Zaki, Kamal Tabti, Mohamed Ouabane, Hanane Zaki, Abdelouahid Sbai, Chakib Sekkate, Tahar Lakhlifi, Mohammed Bouachrine |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-05-01
|
| Series: | Discover Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s44371-025-00205-z |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Py-CoMSIA: An Open-Source Implementation of Comparative Molecular Similarity Indices Analysis in Python
by: Christopher L. Haga, et al.
Published: (2025-03-01) -
Rational design of novel phenol ether derivatives as non-covalent proteasome inhibitors through 3D-QSAR, molecular docking and ADMET prediction
by: Miao Yuan, et al.
Published: (2023-12-01) -
Hybrid 2D/3D-quantitative structure–activity relationship studies on the bioactivities and molecular mechanism of antibacterial peptides
by: Qingguo Yan, et al.
Published: (2024-02-01) -
Discovering New Tyrosinase Inhibitors by Using In Silico Modelling, Molecular Docking, and Molecular Dynamics
by: Kevin A. OréMaldonado, et al.
Published: (2025-03-01) -
Cheminformatics approaches to predict the bioactivity and to discover the pharmacophoric traits crucial to block NF-κB
by: Rahul D. Jawarkar, et al.
Published: (2024-12-01)