The effect of patterns of infectiousness on epidemic size

In the course of an infectious disease in a population, each infected individual presents a different pattern of progress through the disease,producing a corresponding pattern of infectiousness. We postulate a stochasticinfectiousness process for each individual with an almost surely finite integral...

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Main Authors: Luis F. Gordillo, Stephen A. Marion, Priscilla E. Greenwood
Format: Article
Language:English
Published: AIMS Press 2008-05-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2008.5.429
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author Luis F. Gordillo
Stephen A. Marion
Priscilla E. Greenwood
author_facet Luis F. Gordillo
Stephen A. Marion
Priscilla E. Greenwood
author_sort Luis F. Gordillo
collection DOAJ
description In the course of an infectious disease in a population, each infected individual presents a different pattern of progress through the disease,producing a corresponding pattern of infectiousness. We postulate a stochasticinfectiousness process for each individual with an almost surely finite integral,or total infectiousness. Individuals also have different contact rates. We showthat the distribution of the final epidemic size depends only on the contact ratesand the integrated infectiousness. As a particular case, zero infectiousness onan initial time interval corresponds to a period of latency, which does not affectthe final epidemic size in general stochastic and deterministic epidemic models,as is well known from the literature.
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spelling doaj-art-54625ebc19fd4e1d83c0b35a748787782025-01-24T01:58:23ZengAIMS PressMathematical Biosciences and Engineering1551-00182008-05-015342943510.3934/mbe.2008.5.429The effect of patterns of infectiousness on epidemic sizeLuis F. Gordillo0Stephen A. Marion1Priscilla E. Greenwood2Department of Mathematical Sciences, University of Puerto Rico-RUMDepartment of Mathematical Sciences, University of Puerto Rico-RUMDepartment of Mathematical Sciences, University of Puerto Rico-RUMIn the course of an infectious disease in a population, each infected individual presents a different pattern of progress through the disease,producing a corresponding pattern of infectiousness. We postulate a stochasticinfectiousness process for each individual with an almost surely finite integral,or total infectiousness. Individuals also have different contact rates. We showthat the distribution of the final epidemic size depends only on the contact ratesand the integrated infectiousness. As a particular case, zero infectiousness onan initial time interval corresponds to a period of latency, which does not affectthe final epidemic size in general stochastic and deterministic epidemic models,as is well known from the literature.https://www.aimspress.com/article/doi/10.3934/mbe.2008.5.429random infectiousnessvariableinfectiousnessfinal epidemic size.
spellingShingle Luis F. Gordillo
Stephen A. Marion
Priscilla E. Greenwood
The effect of patterns of infectiousness on epidemic size
Mathematical Biosciences and Engineering
random infectiousness
variableinfectiousness
final epidemic size.
title The effect of patterns of infectiousness on epidemic size
title_full The effect of patterns of infectiousness on epidemic size
title_fullStr The effect of patterns of infectiousness on epidemic size
title_full_unstemmed The effect of patterns of infectiousness on epidemic size
title_short The effect of patterns of infectiousness on epidemic size
title_sort effect of patterns of infectiousness on epidemic size
topic random infectiousness
variableinfectiousness
final epidemic size.
url https://www.aimspress.com/article/doi/10.3934/mbe.2008.5.429
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