Types of intrapartum hypoxia in the newborn at term with metabolic acidemia: A retrospective study

Abstract Introduction In the most recent recommendations of the International Federation of Gynecology and Obstetrics (FIGO), a chapter was dedicated to the physiological approach and to the description of fetal mechanisms developed to respond to hypoxia. Our objective was to classify the type of hy...

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Main Authors: Léa Descourvieres, Louise Ghesquiere, Elodie Drumez, Claire Martin, Audrey Sauvage, Damien Subtil, Véronique Houfflin‐Debarge, Charles Garabedian
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Acta Obstetricia et Gynecologica Scandinavica
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Online Access:https://doi.org/10.1111/aogs.14436
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author Léa Descourvieres
Louise Ghesquiere
Elodie Drumez
Claire Martin
Audrey Sauvage
Damien Subtil
Véronique Houfflin‐Debarge
Charles Garabedian
author_facet Léa Descourvieres
Louise Ghesquiere
Elodie Drumez
Claire Martin
Audrey Sauvage
Damien Subtil
Véronique Houfflin‐Debarge
Charles Garabedian
author_sort Léa Descourvieres
collection DOAJ
description Abstract Introduction In the most recent recommendations of the International Federation of Gynecology and Obstetrics (FIGO), a chapter was dedicated to the physiological approach and to the description of fetal mechanisms developed to respond to hypoxia. Our objective was to classify the type of hypoxia in the case of metabolic acidemia and to describe the order of appearance of fetal heart rate abnormalities in cases of gradually evolving hypoxia. Material and methods 132 neonates born between 2018 and 2020 with acidemia were included. We excluded preterm birth, fetuses with congenital anomaly and twin pregnancies. Intrapartum cardiotocography traces were assigned to one of these four types of labor hypoxia: acute, subacute, gradually evolving and chronic hypoxia. For gradually evolving hypoxia, fetal heart rate abnormalities were described according to the FIGO classification. Results 36 cardiotocography traces (27.3%) were classified as acute hypoxia, 14 (10.6%) as subacute hypoxia, and 3 (3.2%) as chronic hypoxia; gradually evolving hypoxia occurred in 62 cases (47%). In 77.4% of cases of gradually evolving hypoxia, deceleration was the first anomaly to appear, with loss of variability and bradycardia appearing later. Increased fetal heart rate was observed immediately after late deceleration in 46.8% of cases and was followed by a loss of variability or saltatory rhythm in 37.1% of cases. Conclusions In cases of metabolic acidemia at term, the most frequent situation observed was gradually evolving hypoxia, with an initial occurrence of decelerations. The sequence of fetal heart rate modifications was variable.
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spelling doaj-art-5438ea4de5e44aae8d03d9c320fbfc2e2025-08-20T02:09:28ZengWileyActa Obstetricia et Gynecologica Scandinavica0001-63491600-04122022-11-01101111276128110.1111/aogs.14436Types of intrapartum hypoxia in the newborn at term with metabolic acidemia: A retrospective studyLéa Descourvieres0Louise Ghesquiere1Elodie Drumez2Claire Martin3Audrey Sauvage4Damien Subtil5Véronique Houfflin‐Debarge6Charles Garabedian7Obstetrics Center Jeanne de Flandre Hospital, CHRU Lille Lille FranceObstetrics Center Jeanne de Flandre Hospital, CHRU Lille Lille FranceDepartment of Biostatistics, EA2694 Public Health: Epidemiology and Quality of Care University of Lille, University Hospital Center (CHU) Lille Lille FranceDepartment of Biostatistics, EA2694 Public Health: Epidemiology and Quality of Care University of Lille, University Hospital Center (CHU) Lille Lille FranceObstetrics Center Jeanne de Flandre Hospital, CHRU Lille Lille FranceObstetrics Center, EA 4489 – Perinatal Environment and Health Jeanne de Flandre Hospital, CHRU Lille, University Lille Lille FranceObstetrics Center Jeanne de Flandre Hospital, CHRU Lille Lille FranceObstetrics Center Jeanne de Flandre Hospital, CHRU Lille Lille FranceAbstract Introduction In the most recent recommendations of the International Federation of Gynecology and Obstetrics (FIGO), a chapter was dedicated to the physiological approach and to the description of fetal mechanisms developed to respond to hypoxia. Our objective was to classify the type of hypoxia in the case of metabolic acidemia and to describe the order of appearance of fetal heart rate abnormalities in cases of gradually evolving hypoxia. Material and methods 132 neonates born between 2018 and 2020 with acidemia were included. We excluded preterm birth, fetuses with congenital anomaly and twin pregnancies. Intrapartum cardiotocography traces were assigned to one of these four types of labor hypoxia: acute, subacute, gradually evolving and chronic hypoxia. For gradually evolving hypoxia, fetal heart rate abnormalities were described according to the FIGO classification. Results 36 cardiotocography traces (27.3%) were classified as acute hypoxia, 14 (10.6%) as subacute hypoxia, and 3 (3.2%) as chronic hypoxia; gradually evolving hypoxia occurred in 62 cases (47%). In 77.4% of cases of gradually evolving hypoxia, deceleration was the first anomaly to appear, with loss of variability and bradycardia appearing later. Increased fetal heart rate was observed immediately after late deceleration in 46.8% of cases and was followed by a loss of variability or saltatory rhythm in 37.1% of cases. Conclusions In cases of metabolic acidemia at term, the most frequent situation observed was gradually evolving hypoxia, with an initial occurrence of decelerations. The sequence of fetal heart rate modifications was variable.https://doi.org/10.1111/aogs.14436chemoreflexdecelerationfetal heart ratehypoxiaintrapartum CTGneonatal acidemia
spellingShingle Léa Descourvieres
Louise Ghesquiere
Elodie Drumez
Claire Martin
Audrey Sauvage
Damien Subtil
Véronique Houfflin‐Debarge
Charles Garabedian
Types of intrapartum hypoxia in the newborn at term with metabolic acidemia: A retrospective study
Acta Obstetricia et Gynecologica Scandinavica
chemoreflex
deceleration
fetal heart rate
hypoxia
intrapartum CTG
neonatal acidemia
title Types of intrapartum hypoxia in the newborn at term with metabolic acidemia: A retrospective study
title_full Types of intrapartum hypoxia in the newborn at term with metabolic acidemia: A retrospective study
title_fullStr Types of intrapartum hypoxia in the newborn at term with metabolic acidemia: A retrospective study
title_full_unstemmed Types of intrapartum hypoxia in the newborn at term with metabolic acidemia: A retrospective study
title_short Types of intrapartum hypoxia in the newborn at term with metabolic acidemia: A retrospective study
title_sort types of intrapartum hypoxia in the newborn at term with metabolic acidemia a retrospective study
topic chemoreflex
deceleration
fetal heart rate
hypoxia
intrapartum CTG
neonatal acidemia
url https://doi.org/10.1111/aogs.14436
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