Diagnostic considerations for gastrointestinal stromal tumors with altered immunophenotype following Imatinib treatment: A case report and literature review

Diagnostic considerations for gastrointestinal stromal tumors with altered immunophenotype following Imatinib treatment: A case report and literature review

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the gastrointestinal tract and have a high rate of recurrence and metastasis. Using an immunohistochemical (IHC) panel including KIT/CD117 and DOG1 allows for accurate diagnosis in more than 98% of cases. However, afte...

Full description

Saved in:
Bibliographic Details
Main Authors: Jihuan Chen, Liz M. Yang, Jonathan Somma, Yujun Gan, Zengying Wu, Zhiyan Fu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Human Pathology Reports
Subjects:
Gastrointestinal stromal tumors (GISTs)
CD117
DOG1
Imatinib
c-KIT
Immunohistochemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2772736X25000088
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items