The Role of Gender in the Importance of Risk Factors for Coronary Artery Disease
Identification of risk factors and their importance in different genders is essential in order to prevent, diagnose, and manage coronary artery disease (CAD) properly. The present study aims to investigate the role of gender in the distribution of different risk factors in ischemic heart disease. Th...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2020/6527820 |
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| author | Farshid Gheisari Melika Emami Hadi Raeisi Shahraki Saeid Samipour Parastoo Nematollahi |
| author_facet | Farshid Gheisari Melika Emami Hadi Raeisi Shahraki Saeid Samipour Parastoo Nematollahi |
| author_sort | Farshid Gheisari |
| collection | DOAJ |
| description | Identification of risk factors and their importance in different genders is essential in order to prevent, diagnose, and manage coronary artery disease (CAD) properly. The present study aims to investigate the role of gender in the distribution of different risk factors in ischemic heart disease. This study is a cross-sectional study. More than one thousand (N = 1012) patients referring to the Nuclear Medicine Department in Namazi Hospital, Shiraz, Iran, from March 2017 to March 2018 were studied. The patients’ demographic data and their clinical history were collected. The results of the myocardial perfusion scan were recorded and compared between groups. Statistical analysis was implemented by SPSS version 18.0, and P values below 0.05 were considered statistically significant. Out of the 1012 patients participating in this study, 698 (69%) were female and 314 (31%) were male. Ischemic heart disease (IHD) was significantly higher in men compared to women (19.1% versus 14.2%). The higher levels of systolic and diastolic blood pressures, along with older age, were a significant risk factor in women P<0.05. Previous myocardial infarction (MI), diabetes mellitus (DM), hypertension (HTN), and hyperlipidemia (HLP) had a strong correlation with IHD in our female population. Regarding the male subjects, previous MI and HLP had a lower correlation with IHD. Based on our logistic regression models, investigation of the simultaneous effects of risk factors on IHD showed that previous MI is the most effective risk factor in females (OR = 3.93) mostly in terms of residual ischemia in the infarcted myocardium. In the male population, on the other hand, HTN was identified as the most effective risk factor for IHD (OR = 2). In conclusion, we found that older age, higher blood pressure, DM, previous MI, HTN, and HLP have a significant association with IHD in the female population, whereas older age, DM, and HTN were significant risk factors for IHD in males. Also, the most effective factor for women was previous MI, while it was HTN for the male population. |
| format | Article |
| id | doaj-art-542446867c08414186ce66c6459b40f1 |
| institution | Kabale University |
| issn | 2090-8016 2090-0597 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-542446867c08414186ce66c6459b40f12025-02-03T01:05:16ZengWileyCardiology Research and Practice2090-80162090-05972020-01-01202010.1155/2020/65278206527820The Role of Gender in the Importance of Risk Factors for Coronary Artery DiseaseFarshid Gheisari0Melika Emami1Hadi Raeisi Shahraki2Saeid Samipour3Parastoo Nematollahi4Ionizing and Non-Ionizing Radiation Protection Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, IranIonizing and Non-Ionizing Radiation Protection Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Epidemiology and Biostatistics, Faculty of Health, Shahrekord University of Medical Sciences, Shahrekord, IranDepartment of Chemical Engineering, School of Chemical and Petroleum Engineering, Shiraz University, Shiraz, IranSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, IranIdentification of risk factors and their importance in different genders is essential in order to prevent, diagnose, and manage coronary artery disease (CAD) properly. The present study aims to investigate the role of gender in the distribution of different risk factors in ischemic heart disease. This study is a cross-sectional study. More than one thousand (N = 1012) patients referring to the Nuclear Medicine Department in Namazi Hospital, Shiraz, Iran, from March 2017 to March 2018 were studied. The patients’ demographic data and their clinical history were collected. The results of the myocardial perfusion scan were recorded and compared between groups. Statistical analysis was implemented by SPSS version 18.0, and P values below 0.05 were considered statistically significant. Out of the 1012 patients participating in this study, 698 (69%) were female and 314 (31%) were male. Ischemic heart disease (IHD) was significantly higher in men compared to women (19.1% versus 14.2%). The higher levels of systolic and diastolic blood pressures, along with older age, were a significant risk factor in women P<0.05. Previous myocardial infarction (MI), diabetes mellitus (DM), hypertension (HTN), and hyperlipidemia (HLP) had a strong correlation with IHD in our female population. Regarding the male subjects, previous MI and HLP had a lower correlation with IHD. Based on our logistic regression models, investigation of the simultaneous effects of risk factors on IHD showed that previous MI is the most effective risk factor in females (OR = 3.93) mostly in terms of residual ischemia in the infarcted myocardium. In the male population, on the other hand, HTN was identified as the most effective risk factor for IHD (OR = 2). In conclusion, we found that older age, higher blood pressure, DM, previous MI, HTN, and HLP have a significant association with IHD in the female population, whereas older age, DM, and HTN were significant risk factors for IHD in males. Also, the most effective factor for women was previous MI, while it was HTN for the male population.http://dx.doi.org/10.1155/2020/6527820 |
| spellingShingle | Farshid Gheisari Melika Emami Hadi Raeisi Shahraki Saeid Samipour Parastoo Nematollahi The Role of Gender in the Importance of Risk Factors for Coronary Artery Disease Cardiology Research and Practice |
| title | The Role of Gender in the Importance of Risk Factors for Coronary Artery Disease |
| title_full | The Role of Gender in the Importance of Risk Factors for Coronary Artery Disease |
| title_fullStr | The Role of Gender in the Importance of Risk Factors for Coronary Artery Disease |
| title_full_unstemmed | The Role of Gender in the Importance of Risk Factors for Coronary Artery Disease |
| title_short | The Role of Gender in the Importance of Risk Factors for Coronary Artery Disease |
| title_sort | role of gender in the importance of risk factors for coronary artery disease |
| url | http://dx.doi.org/10.1155/2020/6527820 |
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