Bilateral Bulky Adrenal Plasmacytomas with Very Good Response to Daratumumab-Based Therapy
Extramedullary myeloma disease represents an infrequent but aggressive variant of multiple myeloma (MM), and it is associated with a poor prognosis. An optimal treatment strategy for this clinical subset has not yet been clarified. In this report, we demonstrate a patient with MM with the uncommon m...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-04-01
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| Series: | Journal of Cancer Research and Practice |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ejcrp.eJCRP-D-22-00027 |
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| _version_ | 1832591026839093248 |
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| author | Fang-Yu Wang Han-Kuang Hsieh Tso-Fu Wang Yi-Feng Wu |
| author_facet | Fang-Yu Wang Han-Kuang Hsieh Tso-Fu Wang Yi-Feng Wu |
| author_sort | Fang-Yu Wang |
| collection | DOAJ |
| description | Extramedullary myeloma disease represents an infrequent but aggressive variant of multiple myeloma (MM), and it is associated with a poor prognosis. An optimal treatment strategy for this clinical subset has not yet been clarified. In this report, we demonstrate a patient with MM with the uncommon manifestation of plasmacytomas with a very high burden in the bilateral adrenal glands at diagnosis, which were treated successfully with daratumumab-based second-line therapy. |
| format | Article |
| id | doaj-art-541fcc4a12ca4406b46a6d3c05aee7a1 |
| institution | Kabale University |
| issn | 2311-3006 |
| language | English |
| publishDate | 2023-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Cancer Research and Practice |
| spelling | doaj-art-541fcc4a12ca4406b46a6d3c05aee7a12025-01-23T05:05:12ZengWolters Kluwer Medknow PublicationsJournal of Cancer Research and Practice2311-30062023-04-01102788110.4103/ejcrp.eJCRP-D-22-00027Bilateral Bulky Adrenal Plasmacytomas with Very Good Response to Daratumumab-Based TherapyFang-Yu WangHan-Kuang HsiehTso-Fu WangYi-Feng WuExtramedullary myeloma disease represents an infrequent but aggressive variant of multiple myeloma (MM), and it is associated with a poor prognosis. An optimal treatment strategy for this clinical subset has not yet been clarified. In this report, we demonstrate a patient with MM with the uncommon manifestation of plasmacytomas with a very high burden in the bilateral adrenal glands at diagnosis, which were treated successfully with daratumumab-based second-line therapy.https://journals.lww.com/10.4103/ejcrp.eJCRP-D-22-00027adrenal plasmacytomadaratumumabextramedullary plasmacytomamultiple myeloma |
| spellingShingle | Fang-Yu Wang Han-Kuang Hsieh Tso-Fu Wang Yi-Feng Wu Bilateral Bulky Adrenal Plasmacytomas with Very Good Response to Daratumumab-Based Therapy Journal of Cancer Research and Practice adrenal plasmacytoma daratumumab extramedullary plasmacytoma multiple myeloma |
| title | Bilateral Bulky Adrenal Plasmacytomas with Very Good Response to Daratumumab-Based Therapy |
| title_full | Bilateral Bulky Adrenal Plasmacytomas with Very Good Response to Daratumumab-Based Therapy |
| title_fullStr | Bilateral Bulky Adrenal Plasmacytomas with Very Good Response to Daratumumab-Based Therapy |
| title_full_unstemmed | Bilateral Bulky Adrenal Plasmacytomas with Very Good Response to Daratumumab-Based Therapy |
| title_short | Bilateral Bulky Adrenal Plasmacytomas with Very Good Response to Daratumumab-Based Therapy |
| title_sort | bilateral bulky adrenal plasmacytomas with very good response to daratumumab based therapy |
| topic | adrenal plasmacytoma daratumumab extramedullary plasmacytoma multiple myeloma |
| url | https://journals.lww.com/10.4103/ejcrp.eJCRP-D-22-00027 |
| work_keys_str_mv | AT fangyuwang bilateralbulkyadrenalplasmacytomaswithverygoodresponsetodaratumumabbasedtherapy AT hankuanghsieh bilateralbulkyadrenalplasmacytomaswithverygoodresponsetodaratumumabbasedtherapy AT tsofuwang bilateralbulkyadrenalplasmacytomaswithverygoodresponsetodaratumumabbasedtherapy AT yifengwu bilateralbulkyadrenalplasmacytomaswithverygoodresponsetodaratumumabbasedtherapy |