Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium
Presentation of tuberculosis (TB) in pregnancy may be atypical with diagnostic challenges. Two patients with complicated pregnancy outcomes, foetal loss and live premature delivery at 5 and 7 months of gestation, respectively, and maternal loss, were diagnosed with pulmonary TB. Chest radiography an...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2015/794109 |
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| author | Zaiyad G. Habib Farouq M. Dayyab Abdallah Sanda Sirajo H. Tambuwal Mahmood M. Dalhat Hamza Muhammad Garba Iliyasu Ibrahim Nashabaru Abdulrazaq G. Habib |
| author_facet | Zaiyad G. Habib Farouq M. Dayyab Abdallah Sanda Sirajo H. Tambuwal Mahmood M. Dalhat Hamza Muhammad Garba Iliyasu Ibrahim Nashabaru Abdulrazaq G. Habib |
| author_sort | Zaiyad G. Habib |
| collection | DOAJ |
| description | Presentation of tuberculosis (TB) in pregnancy may be atypical with diagnostic challenges. Two patients with complicated pregnancy outcomes, foetal loss and live premature delivery at 5 and 7 months of gestation, respectively, and maternal loss, were diagnosed with pulmonary TB. Chest radiography and computed tomography showed widespread reticuloalveolar infiltrates and consolidation with cavitations, respectively. Both patients were Human Immunodeficiency Virus (HIV) seronegative and sputum smear negative for TB. Sputum GeneXpert MTB/Rif (Xpert MTB/RIF) was positive for Mycobacterium tuberculosis. To strengthen maternal and childhood TB control, screening with same-day point-of-care Xpert MTB/RIF is advocated among both HIV positive pregnant women and symptomatic HIV negative pregnant women during antenatal care in pregnancy and at puerperium. |
| format | Article |
| id | doaj-art-540fd8f7795b4c5cb1b384237faa406a |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-540fd8f7795b4c5cb1b384237faa406a2025-02-03T01:09:24ZengWileyCase Reports in Infectious Diseases2090-66252090-66332015-01-01201510.1155/2015/794109794109Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and PuerperiumZaiyad G. Habib0Farouq M. Dayyab1Abdallah Sanda2Sirajo H. Tambuwal3Mahmood M. Dalhat4Hamza Muhammad5Garba Iliyasu6Ibrahim Nashabaru7Abdulrazaq G. Habib8Infectious & Tropical Diseases Unit, Department of Medicine, Aminu Kano Teaching Hospital, PMB 3452, Kano 700233, Kano State, NigeriaInfectious & Tropical Diseases Unit, Department of Medicine, Aminu Kano Teaching Hospital, PMB 3452, Kano 700233, Kano State, NigeriaDepartment of Medical Microbiology, Aminu Kano Teaching Hospital, PMB 3452, Kano 700233, Kano State, NigeriaInfectious & Tropical Diseases Unit, Department of Medicine, Aminu Kano Teaching Hospital, PMB 3452, Kano 700233, Kano State, NigeriaInfectious & Tropical Diseases Unit, Department of Medicine, Aminu Kano Teaching Hospital, PMB 3452, Kano 700233, Kano State, NigeriaInfectious & Tropical Diseases Unit, Department of Medicine, Aminu Kano Teaching Hospital, PMB 3452, Kano 700233, Kano State, NigeriaInfectious & Tropical Diseases Unit, Department of Medicine, Aminu Kano Teaching Hospital, PMB 3452, Kano 700233, Kano State, NigeriaInfectious & Tropical Diseases Unit, Department of Medicine, Aminu Kano Teaching Hospital, PMB 3452, Kano 700233, Kano State, NigeriaInfectious & Tropical Diseases Unit, Department of Medicine, Aminu Kano Teaching Hospital, PMB 3452, Kano 700233, Kano State, NigeriaPresentation of tuberculosis (TB) in pregnancy may be atypical with diagnostic challenges. Two patients with complicated pregnancy outcomes, foetal loss and live premature delivery at 5 and 7 months of gestation, respectively, and maternal loss, were diagnosed with pulmonary TB. Chest radiography and computed tomography showed widespread reticuloalveolar infiltrates and consolidation with cavitations, respectively. Both patients were Human Immunodeficiency Virus (HIV) seronegative and sputum smear negative for TB. Sputum GeneXpert MTB/Rif (Xpert MTB/RIF) was positive for Mycobacterium tuberculosis. To strengthen maternal and childhood TB control, screening with same-day point-of-care Xpert MTB/RIF is advocated among both HIV positive pregnant women and symptomatic HIV negative pregnant women during antenatal care in pregnancy and at puerperium.http://dx.doi.org/10.1155/2015/794109 |
| spellingShingle | Zaiyad G. Habib Farouq M. Dayyab Abdallah Sanda Sirajo H. Tambuwal Mahmood M. Dalhat Hamza Muhammad Garba Iliyasu Ibrahim Nashabaru Abdulrazaq G. Habib Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium Case Reports in Infectious Diseases |
| title | Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium |
| title_full | Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium |
| title_fullStr | Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium |
| title_full_unstemmed | Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium |
| title_short | Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium |
| title_sort | role of genexpert mtb rif assay in diagnosing tuberculosis in pregnancy and puerperium |
| url | http://dx.doi.org/10.1155/2015/794109 |
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