Hypocomplementemic urticarial vasculitis syndrome: A disease with many faces
Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a rare autoimmune disease process where the exact pathogenesis is not known. It is an independent immunological condition affecting multiple organ systems. Major manifestations include chronic urticarial vasculitis (UV) with complement defi...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2019-01-01
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| Series: | Indian Journal of Rheumatology |
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| Online Access: | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2019;volume=14;issue=4;spage=317;epage=320;aulast=Agrawal |
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| _version_ | 1832544401186881536 |
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| author | Ankit Agrawal Sangeetha Pabolu Shirisha Ale Yesenia Galan |
| author_facet | Ankit Agrawal Sangeetha Pabolu Shirisha Ale Yesenia Galan |
| author_sort | Ankit Agrawal |
| collection | DOAJ |
| description | Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a rare autoimmune disease process where the exact pathogenesis is not known. It is an independent immunological condition affecting multiple organ systems. Major manifestations include chronic urticarial vasculitis (UV) with complement deficiency and demonstration of serum C1q antibodies. We describe a case of a 60-year-old male who presented with a generalized rash and was eventually diagnosed with HUVS. Usually, HUVS and systemic lupus erythematosus (SLE) have overlapping features, and our case was unique as our patient did not have any SLE manifestations. This article emphasizes the importance of comprehensive review of systemic manifestations accompanying UV. Although rare, it raises the awareness among the physicians about its clinical presentation and diagnostic approach and also predicts the prognosis of the same. |
| format | Article |
| id | doaj-art-53f1db1ab4d14f1a8e55d544de5eef4c |
| institution | Kabale University |
| issn | 0973-3698 0973-3701 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Indian Journal of Rheumatology |
| spelling | doaj-art-53f1db1ab4d14f1a8e55d544de5eef4c2025-02-03T10:23:16ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012019-01-0114431732010.4103/injr.injr_65_19Hypocomplementemic urticarial vasculitis syndrome: A disease with many facesAnkit AgrawalSangeetha PaboluShirisha AleYesenia GalanHypocomplementemic urticarial vasculitis syndrome (HUVS) is a rare autoimmune disease process where the exact pathogenesis is not known. It is an independent immunological condition affecting multiple organ systems. Major manifestations include chronic urticarial vasculitis (UV) with complement deficiency and demonstration of serum C1q antibodies. We describe a case of a 60-year-old male who presented with a generalized rash and was eventually diagnosed with HUVS. Usually, HUVS and systemic lupus erythematosus (SLE) have overlapping features, and our case was unique as our patient did not have any SLE manifestations. This article emphasizes the importance of comprehensive review of systemic manifestations accompanying UV. Although rare, it raises the awareness among the physicians about its clinical presentation and diagnostic approach and also predicts the prognosis of the same.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2019;volume=14;issue=4;spage=317;epage=320;aulast=Agrawalautoimmunityhypocomplementemiamcduffie syndromeurticarial vasculitis |
| spellingShingle | Ankit Agrawal Sangeetha Pabolu Shirisha Ale Yesenia Galan Hypocomplementemic urticarial vasculitis syndrome: A disease with many faces Indian Journal of Rheumatology autoimmunity hypocomplementemia mcduffie syndrome urticarial vasculitis |
| title | Hypocomplementemic urticarial vasculitis syndrome: A disease with many faces |
| title_full | Hypocomplementemic urticarial vasculitis syndrome: A disease with many faces |
| title_fullStr | Hypocomplementemic urticarial vasculitis syndrome: A disease with many faces |
| title_full_unstemmed | Hypocomplementemic urticarial vasculitis syndrome: A disease with many faces |
| title_short | Hypocomplementemic urticarial vasculitis syndrome: A disease with many faces |
| title_sort | hypocomplementemic urticarial vasculitis syndrome a disease with many faces |
| topic | autoimmunity hypocomplementemia mcduffie syndrome urticarial vasculitis |
| url | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2019;volume=14;issue=4;spage=317;epage=320;aulast=Agrawal |
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