The emergence of nanoporous materials in lung cancer therapy

Lung cancer is one of the most common cancers, affecting more than 2.1 million people across the globe every year. A very high occurrence and mortality rate of lung cancer have prompted active research in this area with both conventional and novel forms of therapies including the use of nanomaterial...

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Main Authors: Deepika Radhakrishnan, Shan Mohanan, Goeun Choi, Jin-Ho Choy, Steffi Tiburcius, Hoang Trung Trinh, Shankar Bolan, Nikki Verrills, Pradeep Tanwar, Ajay Karakoti, Ajayan Vinu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Science and Technology of Advanced Materials
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Online Access:https://www.tandfonline.com/doi/10.1080/14686996.2022.2052181
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author Deepika Radhakrishnan
Shan Mohanan
Goeun Choi
Jin-Ho Choy
Steffi Tiburcius
Hoang Trung Trinh
Shankar Bolan
Nikki Verrills
Pradeep Tanwar
Ajay Karakoti
Ajayan Vinu
author_facet Deepika Radhakrishnan
Shan Mohanan
Goeun Choi
Jin-Ho Choy
Steffi Tiburcius
Hoang Trung Trinh
Shankar Bolan
Nikki Verrills
Pradeep Tanwar
Ajay Karakoti
Ajayan Vinu
author_sort Deepika Radhakrishnan
collection DOAJ
description Lung cancer is one of the most common cancers, affecting more than 2.1 million people across the globe every year. A very high occurrence and mortality rate of lung cancer have prompted active research in this area with both conventional and novel forms of therapies including the use of nanomaterials based drug delivery agents. Specifically, the unique physico-chemical and biological properties of porous nanomaterials have gained significant momentum as drug delivery agents for delivering a combination of drugs or merging diagnosis with targeted therapy for cancer treatment. This review focuses on the emergence of nano-porous materials for drug delivery in lung cancer. The review analyses the currently used nanoporous materials, including inorganic, organic and hybrid porous materials for delivering drugs for various types of therapies, including chemo, radio and phototherapy. It also analyses the selected research on stimuli-responsive nanoporous materials for drug delivery in lung cancer before summarizing the various findings and projecting the future of emerging trends. This review provides a strong foundation for the current status of the research on nanoporous materials, their limitations and the potential for improving their design to overcome the unique challenges of delivering drugs for the treatment of lung cancer.
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publisher Taylor & Francis Group
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spelling doaj-art-53b4fa94a8a24c7db8f10e2d05efa9e02025-08-20T02:26:40ZengTaylor & Francis GroupScience and Technology of Advanced Materials1468-69961878-55142022-12-0123122527410.1080/14686996.2022.2052181The emergence of nanoporous materials in lung cancer therapyDeepika Radhakrishnan0Shan Mohanan1Goeun Choi2Jin-Ho Choy3Steffi Tiburcius4Hoang Trung Trinh5Shankar Bolan6Nikki Verrills7Pradeep Tanwar8Ajay Karakoti9Ajayan Vinu10Global Innovative Centre for Advanced Nanomaterials, College of Engineering, Science and Environment, School of Engineering, The University of Newcastle, Callaghan, NSW, 2308, AustraliaGlobal Innovative Centre for Advanced Nanomaterials, College of Engineering, Science and Environment, School of Engineering, The University of Newcastle, Callaghan, NSW, 2308, AustraliaGlobal Innovative Centre for Advanced Nanomaterials, College of Engineering, Science and Environment, School of Engineering, The University of Newcastle, Callaghan, NSW, 2308, AustraliaGlobal Innovative Centre for Advanced Nanomaterials, College of Engineering, Science and Environment, School of Engineering, The University of Newcastle, Callaghan, NSW, 2308, AustraliaGlobal Innovative Centre for Advanced Nanomaterials, College of Engineering, Science and Environment, School of Engineering, The University of Newcastle, Callaghan, NSW, 2308, AustraliaGlobal Innovative Centre for Advanced Nanomaterials, College of Engineering, Science and Environment, School of Engineering, The University of Newcastle, Callaghan, NSW, 2308, AustraliaGlobal Innovative Centre for Advanced Nanomaterials, College of Engineering, Science and Environment, School of Engineering, The University of Newcastle, Callaghan, NSW, 2308, AustraliaGlobal Innovative Centre for Advanced Nanomaterials, College of Engineering, Science and Environment, School of Engineering, The University of Newcastle, Callaghan, NSW, 2308, AustraliaGlobal Innovative Centre for Advanced Nanomaterials, College of Engineering, Science and Environment, School of Engineering, The University of Newcastle, Callaghan, NSW, 2308, AustraliaGlobal Innovative Centre for Advanced Nanomaterials, College of Engineering, Science and Environment, School of Engineering, The University of Newcastle, Callaghan, NSW, 2308, AustraliaGlobal Innovative Centre for Advanced Nanomaterials, College of Engineering, Science and Environment, School of Engineering, The University of Newcastle, Callaghan, NSW, 2308, AustraliaLung cancer is one of the most common cancers, affecting more than 2.1 million people across the globe every year. A very high occurrence and mortality rate of lung cancer have prompted active research in this area with both conventional and novel forms of therapies including the use of nanomaterials based drug delivery agents. Specifically, the unique physico-chemical and biological properties of porous nanomaterials have gained significant momentum as drug delivery agents for delivering a combination of drugs or merging diagnosis with targeted therapy for cancer treatment. This review focuses on the emergence of nano-porous materials for drug delivery in lung cancer. The review analyses the currently used nanoporous materials, including inorganic, organic and hybrid porous materials for delivering drugs for various types of therapies, including chemo, radio and phototherapy. It also analyses the selected research on stimuli-responsive nanoporous materials for drug delivery in lung cancer before summarizing the various findings and projecting the future of emerging trends. This review provides a strong foundation for the current status of the research on nanoporous materials, their limitations and the potential for improving their design to overcome the unique challenges of delivering drugs for the treatment of lung cancer.https://www.tandfonline.com/doi/10.1080/14686996.2022.2052181Nanoporous materialsdrug deliverylung cancerinorganic nanoporous materialsOrganic nanoporous materialsstimuli responsive
spellingShingle Deepika Radhakrishnan
Shan Mohanan
Goeun Choi
Jin-Ho Choy
Steffi Tiburcius
Hoang Trung Trinh
Shankar Bolan
Nikki Verrills
Pradeep Tanwar
Ajay Karakoti
Ajayan Vinu
The emergence of nanoporous materials in lung cancer therapy
Science and Technology of Advanced Materials
Nanoporous materials
drug delivery
lung cancer
inorganic nanoporous materials
Organic nanoporous materials
stimuli responsive
title The emergence of nanoporous materials in lung cancer therapy
title_full The emergence of nanoporous materials in lung cancer therapy
title_fullStr The emergence of nanoporous materials in lung cancer therapy
title_full_unstemmed The emergence of nanoporous materials in lung cancer therapy
title_short The emergence of nanoporous materials in lung cancer therapy
title_sort emergence of nanoporous materials in lung cancer therapy
topic Nanoporous materials
drug delivery
lung cancer
inorganic nanoporous materials
Organic nanoporous materials
stimuli responsive
url https://www.tandfonline.com/doi/10.1080/14686996.2022.2052181
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