Trends in clinical encounters and management for infertility among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011 to 2021

Objective To examine longitudinal trends in infertility management in women attending general practice.Design Cohort study using the national general practice dataset, MedicineInsight.Setting Australian general practice.Intervention(s) Not applicable.Participants The cohort included 2 552 339 women...

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Main Authors: Alice R Rumbold, Michael Davies, Danielle Mazza, Jacqueline Boyle, Vivienne Moore, Renae C Fernandez, Luke E Grzeskowiak
Format: Article
Language:English
Published: BMJ Publishing Group 2025-02-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/2/e085149.full
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author Alice R Rumbold
Michael Davies
Danielle Mazza
Jacqueline Boyle
Vivienne Moore
Renae C Fernandez
Luke E Grzeskowiak
author_facet Alice R Rumbold
Michael Davies
Danielle Mazza
Jacqueline Boyle
Vivienne Moore
Renae C Fernandez
Luke E Grzeskowiak
author_sort Alice R Rumbold
collection DOAJ
description Objective To examine longitudinal trends in infertility management in women attending general practice.Design Cohort study using the national general practice dataset, MedicineInsight.Setting Australian general practice.Intervention(s) Not applicable.Participants The cohort included 2 552 339 women aged 18–49 years with one or more general practice clinical encounters between January 2011 and December 2021.Primary and secondary outcome measures(s) The primary outcome assessed was the proportion of women who had a clinical encounter related to infertility, stratified by year and age group. Second, the proportions of women receiving relevant clinical management actions, including selected pathology tests, imaging ordered and selected medications, were calculated. Univariable logistic regression analyses compared the likelihood of women having a documented clinical encounter related to infertility and receiving selected management actions based on individual characteristics. We also examined practice-level variation in the proportion receiving selected management for infertility by stratifying proportions based on practice site.Results A total of 2 552 339 women had one or more clinical encounters with their general practitioner (GP) between January 2011 and December 2021, of which 27 671 (1.1%) had a clinical encounter related to infertility management. The rate of infertility encounters increased from 3.4 per 1000 in 2011 to 5.7 per 1000 in 2021. Over episodes of care, half (50.9%) of women presenting for an infertility encounter had at least one specified pathology test, and almost a quarter (23.1%) had a specified imaging test. A relatively small proportion of infertility encounters (5.4%) resulted in prescribing of a selected infertility medication by the GP.Large variation in clinical management (pathology, imaging and medication prescribing) was evident according to both individual characteristics and also at the clinical-practice level. Factors associated with increased likelihood of being provided infertility medications included younger age, holding a Commonwealth concession card (indicating low income), lower socioeconomic status and living outside a major city.Conclusions Clinical encounters related to infertility are increasing in primary care, with large variation evident in corresponding clinical management. These findings support the development of clinical practice guidelines to enhance standardised and equitable approaches towards the management of infertility in primary care.
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spelling doaj-art-5391c393717944a9b0a139d7302416d32025-02-03T15:55:09ZengBMJ Publishing GroupBMJ Open2044-60552025-02-0115210.1136/bmjopen-2024-085149Trends in clinical encounters and management for infertility among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011 to 2021Alice R Rumbold0Michael Davies1Danielle Mazza2Jacqueline Boyle3Vivienne Moore4Renae C Fernandez5Luke E Grzeskowiak6Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, AustraliaRobinson Research Institute, The University of Adelaide, Adelaide, South Australia, AustraliaDepartment of General Practice, Monash University, Clayton, Victoria, AustraliaEastern Health Clinical School, Monash University, Box Hill, Victoria, AustraliaRobinson Research Institute, The University of Adelaide, Adelaide, South Australia, AustraliaRobinson Research Institute, The University of Adelaide, Adelaide, South Australia, AustraliaSouth Australian Health and Medical Research Institute, Adelaide, South Australia, AustraliaObjective To examine longitudinal trends in infertility management in women attending general practice.Design Cohort study using the national general practice dataset, MedicineInsight.Setting Australian general practice.Intervention(s) Not applicable.Participants The cohort included 2 552 339 women aged 18–49 years with one or more general practice clinical encounters between January 2011 and December 2021.Primary and secondary outcome measures(s) The primary outcome assessed was the proportion of women who had a clinical encounter related to infertility, stratified by year and age group. Second, the proportions of women receiving relevant clinical management actions, including selected pathology tests, imaging ordered and selected medications, were calculated. Univariable logistic regression analyses compared the likelihood of women having a documented clinical encounter related to infertility and receiving selected management actions based on individual characteristics. We also examined practice-level variation in the proportion receiving selected management for infertility by stratifying proportions based on practice site.Results A total of 2 552 339 women had one or more clinical encounters with their general practitioner (GP) between January 2011 and December 2021, of which 27 671 (1.1%) had a clinical encounter related to infertility management. The rate of infertility encounters increased from 3.4 per 1000 in 2011 to 5.7 per 1000 in 2021. Over episodes of care, half (50.9%) of women presenting for an infertility encounter had at least one specified pathology test, and almost a quarter (23.1%) had a specified imaging test. A relatively small proportion of infertility encounters (5.4%) resulted in prescribing of a selected infertility medication by the GP.Large variation in clinical management (pathology, imaging and medication prescribing) was evident according to both individual characteristics and also at the clinical-practice level. Factors associated with increased likelihood of being provided infertility medications included younger age, holding a Commonwealth concession card (indicating low income), lower socioeconomic status and living outside a major city.Conclusions Clinical encounters related to infertility are increasing in primary care, with large variation evident in corresponding clinical management. These findings support the development of clinical practice guidelines to enhance standardised and equitable approaches towards the management of infertility in primary care.https://bmjopen.bmj.com/content/15/2/e085149.full
spellingShingle Alice R Rumbold
Michael Davies
Danielle Mazza
Jacqueline Boyle
Vivienne Moore
Renae C Fernandez
Luke E Grzeskowiak
Trends in clinical encounters and management for infertility among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011 to 2021
BMJ Open
title Trends in clinical encounters and management for infertility among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011 to 2021
title_full Trends in clinical encounters and management for infertility among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011 to 2021
title_fullStr Trends in clinical encounters and management for infertility among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011 to 2021
title_full_unstemmed Trends in clinical encounters and management for infertility among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011 to 2021
title_short Trends in clinical encounters and management for infertility among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011 to 2021
title_sort trends in clinical encounters and management for infertility among women attending australian general practice a national longitudinal study using medicineinsight 2011 to 2021
url https://bmjopen.bmj.com/content/15/2/e085149.full
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