Idiopathic Intractable Diarrhoea Leading to Torsade de Pointes
An 81-year-old lady was admitted to our hospital with a 3-year history of noninfective diarrhoea and recurrent syncopal events over the last 3 months. Her initial electrocardiogram (ECG) revealed trigeminy and prolonged QTc interval. She had a structurally normal heart with no coronary artery diseas...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2016/3845108 |
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| _version_ | 1832562736723132416 |
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| author | Kyriacos Mouyis Darlington Okonko Constantinos G. Missouris |
| author_facet | Kyriacos Mouyis Darlington Okonko Constantinos G. Missouris |
| author_sort | Kyriacos Mouyis |
| collection | DOAJ |
| description | An 81-year-old lady was admitted to our hospital with a 3-year history of noninfective diarrhoea and recurrent syncopal events over the last 3 months. Her initial electrocardiogram (ECG) revealed trigeminy and prolonged QTc interval. She had a structurally normal heart with no coronary artery disease. Investigations revealed low potassium at 3.0 mmol/L. Sigmoidoscopy and colonoscopy suggested a possible diagnosis of diverticulitis. Soon after admission she had an unresponsive episode with spontaneous recovery. Telemetry and Holter analysis confirmed multiple episodes of polymorphic ventricular tachycardia (Torsade de Pointes). Following electrolyte supplementation the episodes of polymorphic VT improved. Due to the protracted nature of the diarrhoea, the recurrent syncopal events, and recurrent hypokalaemia documented over recent years, an Implantable Cardioverter Defibrillator (ICD) was sanctioned by the multidisciplinary team (MDT). In summary, chronic diarrhoea may result in life threatening polymorphic VT due to hypokalaemia and QTc prolongation. In these patients an ICD may be considered. |
| format | Article |
| id | doaj-art-53830d2d2d2644da98892b0e25d596ee |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-53830d2d2d2644da98892b0e25d596ee2025-02-03T01:21:55ZengWileyCase Reports in Cardiology2090-64042090-64122016-01-01201610.1155/2016/38451083845108Idiopathic Intractable Diarrhoea Leading to Torsade de PointesKyriacos Mouyis0Darlington Okonko1Constantinos G. Missouris2Frimley Health NHS Foundation Trust, Wexham Park Hospital, Cardiology Department, Slough SL2 4HL, UKKing’s College London BHF Centre, King’s College Hospital, London SE1 7EH, UKFrimley Health NHS Foundation Trust, Wexham Park Hospital, Cardiology Department, Slough SL2 4HL, UKAn 81-year-old lady was admitted to our hospital with a 3-year history of noninfective diarrhoea and recurrent syncopal events over the last 3 months. Her initial electrocardiogram (ECG) revealed trigeminy and prolonged QTc interval. She had a structurally normal heart with no coronary artery disease. Investigations revealed low potassium at 3.0 mmol/L. Sigmoidoscopy and colonoscopy suggested a possible diagnosis of diverticulitis. Soon after admission she had an unresponsive episode with spontaneous recovery. Telemetry and Holter analysis confirmed multiple episodes of polymorphic ventricular tachycardia (Torsade de Pointes). Following electrolyte supplementation the episodes of polymorphic VT improved. Due to the protracted nature of the diarrhoea, the recurrent syncopal events, and recurrent hypokalaemia documented over recent years, an Implantable Cardioverter Defibrillator (ICD) was sanctioned by the multidisciplinary team (MDT). In summary, chronic diarrhoea may result in life threatening polymorphic VT due to hypokalaemia and QTc prolongation. In these patients an ICD may be considered.http://dx.doi.org/10.1155/2016/3845108 |
| spellingShingle | Kyriacos Mouyis Darlington Okonko Constantinos G. Missouris Idiopathic Intractable Diarrhoea Leading to Torsade de Pointes Case Reports in Cardiology |
| title | Idiopathic Intractable Diarrhoea Leading to Torsade de Pointes |
| title_full | Idiopathic Intractable Diarrhoea Leading to Torsade de Pointes |
| title_fullStr | Idiopathic Intractable Diarrhoea Leading to Torsade de Pointes |
| title_full_unstemmed | Idiopathic Intractable Diarrhoea Leading to Torsade de Pointes |
| title_short | Idiopathic Intractable Diarrhoea Leading to Torsade de Pointes |
| title_sort | idiopathic intractable diarrhoea leading to torsade de pointes |
| url | http://dx.doi.org/10.1155/2016/3845108 |
| work_keys_str_mv | AT kyriacosmouyis idiopathicintractablediarrhoealeadingtotorsadedepointes AT darlingtonokonko idiopathicintractablediarrhoealeadingtotorsadedepointes AT constantinosgmissouris idiopathicintractablediarrhoealeadingtotorsadedepointes |