Extraction and Processing of Bioactive Phytoconstituents from Widely Used South African Medicinal Plants for the Preparation of Effective Traditional Herbal Medicine Products: A Narrative Review

Medicinal plants are sources of crude traditional herbal medicines that are utilized to reduce the risk of, treat, or manage diseases in most indigenous communities. This is due to their potent antioxidant and anti-inflammatory effects. It is estimated that about 80% of the population in developing...

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Main Authors: Sphamandla Hlatshwayo, Nokukhanya Thembane, Suresh Babu Naidu Krishna, Nceba Gqaleni, Mlungisi Ngcobo
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Plants
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Online Access:https://www.mdpi.com/2223-7747/14/2/206
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author Sphamandla Hlatshwayo
Nokukhanya Thembane
Suresh Babu Naidu Krishna
Nceba Gqaleni
Mlungisi Ngcobo
author_facet Sphamandla Hlatshwayo
Nokukhanya Thembane
Suresh Babu Naidu Krishna
Nceba Gqaleni
Mlungisi Ngcobo
author_sort Sphamandla Hlatshwayo
collection DOAJ
description Medicinal plants are sources of crude traditional herbal medicines that are utilized to reduce the risk of, treat, or manage diseases in most indigenous communities. This is due to their potent antioxidant and anti-inflammatory effects. It is estimated that about 80% of the population in developing countries rely on herbal traditional medicines for healthcare. This signifies the need for traditional herbal medicines, which are polyherbal formulations prepared by traditional health practitioners. This review examines preparatory steps to extract bioactive phytoconstituents and post-extraction processes to increase the potency of the extracted bioactive phytoconstituents. Achieving this will allow for the reduced use of plant materials and promote the sustainable use of the limited resource of medicinal plants, especially in our South African context. Electronic ethnobotanical books and online databases were used to find studies that focus on phytoconstituent extraction and post-extraction processing to enhance the potency of the extracted bioactive phytoconstituents. Modification of the extracted bioactive phytoconstituents to synthesize daughter compounds facilitates an enhancement in their potency and bioavailability. Based on the data collected through this review, the importance of understanding the properties of the targeted phytoconstituents is essential in selecting the required extraction method. This determines the quality and yield of extracted bioactive phytoconstituents.
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institution Kabale University
issn 2223-7747
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spelling doaj-art-5371543963f9407b89ed36e320c030252025-01-24T13:46:45ZengMDPI AGPlants2223-77472025-01-0114220610.3390/plants14020206Extraction and Processing of Bioactive Phytoconstituents from Widely Used South African Medicinal Plants for the Preparation of Effective Traditional Herbal Medicine Products: A Narrative ReviewSphamandla Hlatshwayo0Nokukhanya Thembane1Suresh Babu Naidu Krishna2Nceba Gqaleni3Mlungisi Ngcobo4Traditional Medicine Laboratory, University of KwaZulu Natal, Durban 4041, South AfricaTraditional Medicine Laboratory, University of KwaZulu Natal, Durban 4041, South AfricaInstitute for Water and Wastewater Technology, Durban University of Technology, Durban 4000, South AfricaTraditional Medicine Laboratory, University of KwaZulu Natal, Durban 4041, South AfricaTraditional Medicine Laboratory, University of KwaZulu Natal, Durban 4041, South AfricaMedicinal plants are sources of crude traditional herbal medicines that are utilized to reduce the risk of, treat, or manage diseases in most indigenous communities. This is due to their potent antioxidant and anti-inflammatory effects. It is estimated that about 80% of the population in developing countries rely on herbal traditional medicines for healthcare. This signifies the need for traditional herbal medicines, which are polyherbal formulations prepared by traditional health practitioners. This review examines preparatory steps to extract bioactive phytoconstituents and post-extraction processes to increase the potency of the extracted bioactive phytoconstituents. Achieving this will allow for the reduced use of plant materials and promote the sustainable use of the limited resource of medicinal plants, especially in our South African context. Electronic ethnobotanical books and online databases were used to find studies that focus on phytoconstituent extraction and post-extraction processing to enhance the potency of the extracted bioactive phytoconstituents. Modification of the extracted bioactive phytoconstituents to synthesize daughter compounds facilitates an enhancement in their potency and bioavailability. Based on the data collected through this review, the importance of understanding the properties of the targeted phytoconstituents is essential in selecting the required extraction method. This determines the quality and yield of extracted bioactive phytoconstituents.https://www.mdpi.com/2223-7747/14/2/206medicinal plantsextractionprocessingbioactive phytoconstituentspotency
spellingShingle Sphamandla Hlatshwayo
Nokukhanya Thembane
Suresh Babu Naidu Krishna
Nceba Gqaleni
Mlungisi Ngcobo
Extraction and Processing of Bioactive Phytoconstituents from Widely Used South African Medicinal Plants for the Preparation of Effective Traditional Herbal Medicine Products: A Narrative Review
Plants
medicinal plants
extraction
processing
bioactive phytoconstituents
potency
title Extraction and Processing of Bioactive Phytoconstituents from Widely Used South African Medicinal Plants for the Preparation of Effective Traditional Herbal Medicine Products: A Narrative Review
title_full Extraction and Processing of Bioactive Phytoconstituents from Widely Used South African Medicinal Plants for the Preparation of Effective Traditional Herbal Medicine Products: A Narrative Review
title_fullStr Extraction and Processing of Bioactive Phytoconstituents from Widely Used South African Medicinal Plants for the Preparation of Effective Traditional Herbal Medicine Products: A Narrative Review
title_full_unstemmed Extraction and Processing of Bioactive Phytoconstituents from Widely Used South African Medicinal Plants for the Preparation of Effective Traditional Herbal Medicine Products: A Narrative Review
title_short Extraction and Processing of Bioactive Phytoconstituents from Widely Used South African Medicinal Plants for the Preparation of Effective Traditional Herbal Medicine Products: A Narrative Review
title_sort extraction and processing of bioactive phytoconstituents from widely used south african medicinal plants for the preparation of effective traditional herbal medicine products a narrative review
topic medicinal plants
extraction
processing
bioactive phytoconstituents
potency
url https://www.mdpi.com/2223-7747/14/2/206
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