Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report
Intracranial epidermoid cysts are uncommon benign tumors of developmental origin; malignant transformation of benign epidermoid cysts is rare, and their prognosis remains poor. We report a case of squamous cell carcinoma arising in the cerebellopontine angle. A 52-year-old man presented with left f...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/525289 |
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| author | Fayçal Lakhdar El Mehdi Hakkou Rachid Gana Rachid My Maaqili Fouad Bellakhdar |
| author_facet | Fayçal Lakhdar El Mehdi Hakkou Rachid Gana Rachid My Maaqili Fouad Bellakhdar |
| author_sort | Fayçal Lakhdar |
| collection | DOAJ |
| description | Intracranial epidermoid cysts are uncommon benign tumors of developmental origin; malignant transformation of benign epidermoid cysts is rare, and their prognosis remains poor. We report a case of squamous cell carcinoma arising in the cerebellopontine angle. A 52-year-old man presented with left facial paralysis and cerebellar ataxia. He had undergone total removal of a benign epidermoid cyst six months previously. Postoperative magnetic resonance imaging of the brain revealed a heterogeneous and cystic lesion in the left cerebellopontine angle with hydrocephalus. The cyst wall was enhanced by gadolinium. He underwent ventricle-peritoneal shunt and removal again; the histopathological examination revealed a squamous cell carcinoma possibly arising from an underlying epidermoid cyst. This entity is being reported for its rarity. The presence of contrast enhancement at the site of an epidermoid cyst combined with an acute, progressive neurological deficit should alert the neurosurgeon to the possibility of a malignant transformation. |
| format | Article |
| id | doaj-art-53368f6fbd8144fbb2ce2c622ce29103 |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-53368f6fbd8144fbb2ce2c622ce291032025-02-03T05:50:34ZengWileyCase Reports in Neurological Medicine2090-66682090-66762011-01-01201110.1155/2011/525289525289Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case ReportFayçal Lakhdar0El Mehdi Hakkou1Rachid Gana2Rachid My Maaqili3Fouad Bellakhdar4Department of Neurosurgery, Ibn Sina Hospital, Rabat, MoroccoDepartment of Neurosurgery, Ibn Sina Hospital, Rabat, MoroccoDepartment of Neurosurgery, Ibn Sina Hospital, Rabat, MoroccoDepartment of Neurosurgery, Ibn Sina Hospital, Rabat, MoroccoDepartment of Neurosurgery, Ibn Sina Hospital, Rabat, MoroccoIntracranial epidermoid cysts are uncommon benign tumors of developmental origin; malignant transformation of benign epidermoid cysts is rare, and their prognosis remains poor. We report a case of squamous cell carcinoma arising in the cerebellopontine angle. A 52-year-old man presented with left facial paralysis and cerebellar ataxia. He had undergone total removal of a benign epidermoid cyst six months previously. Postoperative magnetic resonance imaging of the brain revealed a heterogeneous and cystic lesion in the left cerebellopontine angle with hydrocephalus. The cyst wall was enhanced by gadolinium. He underwent ventricle-peritoneal shunt and removal again; the histopathological examination revealed a squamous cell carcinoma possibly arising from an underlying epidermoid cyst. This entity is being reported for its rarity. The presence of contrast enhancement at the site of an epidermoid cyst combined with an acute, progressive neurological deficit should alert the neurosurgeon to the possibility of a malignant transformation.http://dx.doi.org/10.1155/2011/525289 |
| spellingShingle | Fayçal Lakhdar El Mehdi Hakkou Rachid Gana Rachid My Maaqili Fouad Bellakhdar Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report Case Reports in Neurological Medicine |
| title | Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report |
| title_full | Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report |
| title_fullStr | Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report |
| title_full_unstemmed | Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report |
| title_short | Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report |
| title_sort | malignant transformation six months after removal of intracranial epidermoid cyst a case report |
| url | http://dx.doi.org/10.1155/2011/525289 |
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