Recurrent Plasmacytomas after Allografting in a Patient with Multiple Myeloma

Extramedullary recurrence in multiple myeloma patients has been reported after both autologous and allogeneic hematopoietic cell transplantation and, more recently, after treatment with so-called new drugs with potent antimyeloma activity. Only a very few sizable reports focused on its clinical pres...

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Main Authors: Allen N. Stawis, Diane Maennle, Moreno Festuccia, Zia Uddin, Benedetto Bruno
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/168785
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author Allen N. Stawis
Diane Maennle
Moreno Festuccia
Zia Uddin
Benedetto Bruno
author_facet Allen N. Stawis
Diane Maennle
Moreno Festuccia
Zia Uddin
Benedetto Bruno
author_sort Allen N. Stawis
collection DOAJ
description Extramedullary recurrence in multiple myeloma patients has been reported after both autologous and allogeneic hematopoietic cell transplantation and, more recently, after treatment with so-called new drugs with potent antimyeloma activity. Only a very few sizable reports focused on its clinical presentation and its incidence, which may be highly underestimated, and most observations are based on single patients reported from several institutions. Given the unusual sites of recurrence, diagnosis may be rather difficult and delayed treatment may play a relevant role in prognosis. Here we report a case of a myeloma patient, initially treated with an allograft, who enjoyed an eleven-year disease-free remission with very good quality of life. She eventually relapsed first with an extramedullary plasmacytoma in the breast and, two years later, with a right atrial cardiac mass.
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spelling doaj-art-53216f1617ed4f1fbc409a9d9f9219022025-02-03T00:59:08ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/168785168785Recurrent Plasmacytomas after Allografting in a Patient with Multiple MyelomaAllen N. Stawis0Diane Maennle1Moreno Festuccia2Zia Uddin3Benedetto Bruno4Department of Hematology and Oncology, Webber Cancer Center, St. John Macomb-Oakland Hospital, Warren, MI 48093, USADepartment of Clinical Pathology, St. John Macomb-Oakland Hospital, Warren, MI 48093, USADivision of Hematology, University of Torino, Via Genova 3, 10126 Torino, ItalyDepartment of Clinical Pathology, St. John Macomb-Oakland Hospital, Warren, MI 48093, USADivision of Hematology, University of Torino, Via Genova 3, 10126 Torino, ItalyExtramedullary recurrence in multiple myeloma patients has been reported after both autologous and allogeneic hematopoietic cell transplantation and, more recently, after treatment with so-called new drugs with potent antimyeloma activity. Only a very few sizable reports focused on its clinical presentation and its incidence, which may be highly underestimated, and most observations are based on single patients reported from several institutions. Given the unusual sites of recurrence, diagnosis may be rather difficult and delayed treatment may play a relevant role in prognosis. Here we report a case of a myeloma patient, initially treated with an allograft, who enjoyed an eleven-year disease-free remission with very good quality of life. She eventually relapsed first with an extramedullary plasmacytoma in the breast and, two years later, with a right atrial cardiac mass.http://dx.doi.org/10.1155/2012/168785
spellingShingle Allen N. Stawis
Diane Maennle
Moreno Festuccia
Zia Uddin
Benedetto Bruno
Recurrent Plasmacytomas after Allografting in a Patient with Multiple Myeloma
Case Reports in Medicine
title Recurrent Plasmacytomas after Allografting in a Patient with Multiple Myeloma
title_full Recurrent Plasmacytomas after Allografting in a Patient with Multiple Myeloma
title_fullStr Recurrent Plasmacytomas after Allografting in a Patient with Multiple Myeloma
title_full_unstemmed Recurrent Plasmacytomas after Allografting in a Patient with Multiple Myeloma
title_short Recurrent Plasmacytomas after Allografting in a Patient with Multiple Myeloma
title_sort recurrent plasmacytomas after allografting in a patient with multiple myeloma
url http://dx.doi.org/10.1155/2012/168785
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