Bilayer sol-gel system for local prevention in prosthetic joint infections and osteointegration improvement

Bilayer sol-gel system for local prevention in prosthetic joint infections and osteointegration improvement

Abstract Prosthetic joint infection (PJI) is one of the most severe complications associated with arthroplasties. Here we evaluate a bilayer coating system designed for both PJI prevention and osteoinduction. The outer layer is loaded with levofloxacin and linezolid, providing broad-spectrum antibio...

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Main Authors: Antonia Jiménez-Morales, Ángela Solís-Garrido, Beatriz Toirac, Aranzazu Mediero, Bruna Costa, Francisca Mulero, Óscar Murillo, Miguel Monclús, Jaime Esteban, John Jairo Aguilera-Correa
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Materials
Online Access:https://doi.org/10.1038/s43246-025-00790-7
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