Inflammatory Myofibroblastic Tumor of the Trachea with Concomitant Granulomatous Lymph Node Lesions
We report herein the case of a 57-year-old lady who had two concomittant lesions, an inflammatory myofibroblastic tumor in the trachea, and severe granulomatous lesions in the adjacent hilar lymph nodes. While these two lesions shared histological and some immunohistochemical features lesions. They...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/151729 |
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| author | Julia Anne Koch Patrick Dorn Thierry Rausch Hans-Beat Ris Hans-Anton Lehr Stephan C. Schäfer |
| author_facet | Julia Anne Koch Patrick Dorn Thierry Rausch Hans-Beat Ris Hans-Anton Lehr Stephan C. Schäfer |
| author_sort | Julia Anne Koch |
| collection | DOAJ |
| description | We report herein the case of a 57-year-old lady who had two concomittant lesions, an inflammatory myofibroblastic tumor in the trachea, and severe granulomatous lesions in the adjacent hilar lymph nodes. While these two lesions shared histological and some immunohistochemical features lesions. They differed in terms of ALK-1 expression, which was positive in the tracheal tumor and negative in the lymph nodes. The discussion of the case circles around putative pathophysiological links between the lesions. The authors favor the idea that the lymph nodes present a sarcoid-like granulomatous reaction to the inflammatory myofibroblastic tumor in the trachea over a coexistence of two independent entities. However, no conclusive evidence for this interpretation can be presented based on the existing literature. |
| format | Article |
| id | doaj-art-531aeecb35e843c593800f1a145826ec |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-531aeecb35e843c593800f1a145826ec2025-02-03T01:24:35ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/151729151729Inflammatory Myofibroblastic Tumor of the Trachea with Concomitant Granulomatous Lymph Node LesionsJulia Anne Koch0Patrick Dorn1Thierry Rausch2Hans-Beat Ris3Hans-Anton Lehr4Stephan C. Schäfer5Department of Thoracic and Vascular Surgery, CHUV, 1011 Lausanne, SwitzerlandDepartment of Surgery, Kantonsspital Graubünden, 7000 Chur, SwitzerlandInstitute of Pathology, CHUV, 1011 Lausanne, SwitzerlandDepartment of Thoracic and Vascular Surgery, CHUV, 1011 Lausanne, SwitzerlandInstitute of Pathology, CHUV, 1011 Lausanne, SwitzerlandInstitute of Pathology, CHUV, 1011 Lausanne, SwitzerlandWe report herein the case of a 57-year-old lady who had two concomittant lesions, an inflammatory myofibroblastic tumor in the trachea, and severe granulomatous lesions in the adjacent hilar lymph nodes. While these two lesions shared histological and some immunohistochemical features lesions. They differed in terms of ALK-1 expression, which was positive in the tracheal tumor and negative in the lymph nodes. The discussion of the case circles around putative pathophysiological links between the lesions. The authors favor the idea that the lymph nodes present a sarcoid-like granulomatous reaction to the inflammatory myofibroblastic tumor in the trachea over a coexistence of two independent entities. However, no conclusive evidence for this interpretation can be presented based on the existing literature.http://dx.doi.org/10.1155/2011/151729 |
| spellingShingle | Julia Anne Koch Patrick Dorn Thierry Rausch Hans-Beat Ris Hans-Anton Lehr Stephan C. Schäfer Inflammatory Myofibroblastic Tumor of the Trachea with Concomitant Granulomatous Lymph Node Lesions Case Reports in Medicine |
| title | Inflammatory Myofibroblastic Tumor of the Trachea with Concomitant Granulomatous Lymph Node Lesions |
| title_full | Inflammatory Myofibroblastic Tumor of the Trachea with Concomitant Granulomatous Lymph Node Lesions |
| title_fullStr | Inflammatory Myofibroblastic Tumor of the Trachea with Concomitant Granulomatous Lymph Node Lesions |
| title_full_unstemmed | Inflammatory Myofibroblastic Tumor of the Trachea with Concomitant Granulomatous Lymph Node Lesions |
| title_short | Inflammatory Myofibroblastic Tumor of the Trachea with Concomitant Granulomatous Lymph Node Lesions |
| title_sort | inflammatory myofibroblastic tumor of the trachea with concomitant granulomatous lymph node lesions |
| url | http://dx.doi.org/10.1155/2011/151729 |
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