17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line
Aims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory actions of the steroid hormones, the purpose of this stu...
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Format: | Article |
Language: | English |
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Wiley
2001-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1080/09629350120093713 |
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author | Margarida Castro-Caldas Carlos B. Duarte Arsélio P. Carvalho M. Celeste Lopes |
author_facet | Margarida Castro-Caldas Carlos B. Duarte Arsélio P. Carvalho M. Celeste Lopes |
author_sort | Margarida Castro-Caldas |
collection | DOAJ |
description | Aims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory actions of the steroid hormones, the purpose of this study was to investigate the effects of the female sex steroid hormone, 17β-estradiol (E2β), on the synthesis and secretion of ANXA1 in the human CCRF-CEM acute lymphoblastic leukemia cell line. |
format | Article |
id | doaj-art-5317d21a2ca946ee883bddbed2061d5c |
institution | Kabale University |
issn | 0962-9351 1466-1861 |
language | English |
publishDate | 2001-01-01 |
publisher | Wiley |
record_format | Article |
series | Mediators of Inflammation |
spelling | doaj-art-5317d21a2ca946ee883bddbed2061d5c2025-02-03T07:25:34ZengWileyMediators of Inflammation0962-93511466-18612001-01-0110524525110.1080/0962935012009371317β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell lineMargarida Castro-Caldas0Carlos B. Duarte1Arsélio P. Carvalho2M. Celeste Lopes3Center for Neuroscience of Coimbra, Department of Zoology, University of Coimbra, Coimbra 3004–517, PortugalCenter for Neuroscience of Coimbra, Department of Zoology, University of Coimbra, Coimbra 3004–517, PortugalCenter for Neuroscience of Coimbra, Department of Zoology, University of Coimbra, Coimbra 3004–517, PortugalCenter for Neuroscience of Coimbra, Department of Zoology, University of Coimbra, Coimbra 3004–517, PortugalAims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory actions of the steroid hormones, the purpose of this study was to investigate the effects of the female sex steroid hormone, 17β-estradiol (E2β), on the synthesis and secretion of ANXA1 in the human CCRF-CEM acute lymphoblastic leukemia cell line.http://dx.doi.org/10.1080/09629350120093713 |
spellingShingle | Margarida Castro-Caldas Carlos B. Duarte Arsélio P. Carvalho M. Celeste Lopes 17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line Mediators of Inflammation |
title | 17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line |
title_full | 17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line |
title_fullStr | 17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line |
title_full_unstemmed | 17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line |
title_short | 17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line |
title_sort | 17β estradiol promotes the synthesis and the secretion of annexin i in the ccrf cem human cell line |
url | http://dx.doi.org/10.1080/09629350120093713 |
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