17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line

Aims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory actions of the steroid hormones, the purpose of this stu...

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Main Authors: Margarida Castro-Caldas, Carlos B. Duarte, Arsélio P. Carvalho, M. Celeste Lopes
Format: Article
Language:English
Published: Wiley 2001-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350120093713
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author Margarida Castro-Caldas
Carlos B. Duarte
Arsélio P. Carvalho
M. Celeste Lopes
author_facet Margarida Castro-Caldas
Carlos B. Duarte
Arsélio P. Carvalho
M. Celeste Lopes
author_sort Margarida Castro-Caldas
collection DOAJ
description Aims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory actions of the steroid hormones, the purpose of this study was to investigate the effects of the female sex steroid hormone, 17β-estradiol (E2β), on the synthesis and secretion of ANXA1 in the human CCRF-CEM acute lymphoblastic leukemia cell line.
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institution Kabale University
issn 0962-9351
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language English
publishDate 2001-01-01
publisher Wiley
record_format Article
series Mediators of Inflammation
spelling doaj-art-5317d21a2ca946ee883bddbed2061d5c2025-02-03T07:25:34ZengWileyMediators of Inflammation0962-93511466-18612001-01-0110524525110.1080/0962935012009371317β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell lineMargarida Castro-Caldas0Carlos B. Duarte1Arsélio P. Carvalho2M. Celeste Lopes3Center for Neuroscience of Coimbra, Department of Zoology, University of Coimbra, Coimbra 3004–517, PortugalCenter for Neuroscience of Coimbra, Department of Zoology, University of Coimbra, Coimbra 3004–517, PortugalCenter for Neuroscience of Coimbra, Department of Zoology, University of Coimbra, Coimbra 3004–517, PortugalCenter for Neuroscience of Coimbra, Department of Zoology, University of Coimbra, Coimbra 3004–517, PortugalAims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory actions of the steroid hormones, the purpose of this study was to investigate the effects of the female sex steroid hormone, 17β-estradiol (E2β), on the synthesis and secretion of ANXA1 in the human CCRF-CEM acute lymphoblastic leukemia cell line.http://dx.doi.org/10.1080/09629350120093713
spellingShingle Margarida Castro-Caldas
Carlos B. Duarte
Arsélio P. Carvalho
M. Celeste Lopes
17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line
Mediators of Inflammation
title 17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line
title_full 17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line
title_fullStr 17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line
title_full_unstemmed 17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line
title_short 17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line
title_sort 17β estradiol promotes the synthesis and the secretion of annexin i in the ccrf cem human cell line
url http://dx.doi.org/10.1080/09629350120093713
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