17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line
Aims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory actions of the steroid hormones, the purpose of this stu...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2001-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1080/09629350120093713 |
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| Summary: | Aims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory actions of the steroid hormones, the purpose of this study was to investigate the effects of the female sex steroid hormone, 17β-estradiol (E2β), on the synthesis and secretion of ANXA1 in the human CCRF-CEM acute lymphoblastic leukemia cell line. |
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| ISSN: | 0962-9351 1466-1861 |