Generation and propagation of high fecundity gene edited fine wool sheep by CRISPR/Cas9

Generation and propagation of high fecundity gene edited fine wool sheep by CRISPR/Cas9

Abstract CRISPR/Cas9 technology has been widely utilized to enhance productive performance, increase disease resistance and generate medical models in livestock. The FecB allele in sheep is a mutation in the BMPRIB gene, recognized as the first major gene responsible for the high fecundity trait in...

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Bibliographic Details
Main Authors: Xuemei Zhang, Meiyu Qiu, Bing Han, Li Liao, Xinrong Peng, Jiapeng Lin, Ning Zhang, Lati Hai, Long Liang, Yila Ma, Wenrong Li, Mingjun Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
BMPRIB
CRISPR/Cas 9
Fine wool sheep
Gene edited
Online Access:https://doi.org/10.1038/s41598-025-86592-w
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