Effects of Naringin on Proliferation and Osteogenic Differentiation of Human Periodontal Ligament Stem Cells In Vitro and In Vivo

Effects of Naringin on Proliferation and Osteogenic Differentiation of Human Periodontal Ligament Stem Cells In Vitro and In Vivo

This study is to explore the osteogenesis potential of the human periodontal ligament stem cells (hPDLSCs) induced by naringin in vitro and in vitro. The results confirmed that 1 μM naringin performs the best effect and a collection of bone-related genes (RUNX2, COL1A2, OPN, and OCN) had significant...

Full description

Saved in:

Bibliographic Details
Main Authors:	Lihua Yin, Wenxiao Cheng, Zishun Qin, Hongdou Yu, Zhanhai Yu, Mei Zhong, Kemo Sun, Wei Zhang
Format:	Article
Language:	English
Published:	Wiley 2015-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2015/758706
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

MicroRNA functions in osteogenic differentiation of periodontal ligament stem cells: a scoping review
by: Pirawish Limlawan, et al.
Published: (2025-01-01)

lncRNA HHIP-AS1 Promotes the Osteogenic Differentiation Potential and Inhibits the Migration Ability of Periodontal Ligament Stem Cells
by: Qianyi Qin, et al.
Published: (2021-01-01)

Azithromycin Promotes the Osteogenic Differentiation of Human Periodontal Ligament Stem Cells after Stimulation with TNF-α
by: Tingting Meng, et al.
Published: (2018-01-01)

An In Vitro and In Vivo Comparison of Osteogenic Differentiation of Human Mesenchymal Stromal/Stem Cells
by: Jamie Mollentze, et al.
Published: (2021-01-01)

Succinate Supplement Elicited “Pseudohypoxia” Condition to Promote Proliferation, Migration, and Osteogenesis of Periodontal Ligament Cells
by: Huimin Mao, et al.
Published: (2020-01-01)

Enhancement of Anti-Inflammatory and Osteogenic Abilities of Mesenchymal Stem Cells via Cell-to-Cell Adhesion to Periodontal Ligament-Derived Fibroblasts
by: Keita Suzuki, et al.
Published: (2017-01-01)

Regulation of Ghrelin Receptor by Periodontal Bacteria In Vitro and In Vivo
by: Marjan Nokhbehsaim, et al.
Published: (2017-01-01)

Effects of 0.01 mM strontium on human periodontal ligament stem cell osteogenic differentiation via the Wnt/-catenin signaling pathway
by: Tongke Sun, et al.
Published: (2025-02-01)

Role of periodontal ligament fibroblasts in periodontitis: pathological mechanisms and therapeutic potential
by: Yijie Huang, et al.
Published: (2024-12-01)

Rhoifolin Suppresses Cell Proliferation and Induces Apoptosis in Hepatocellular Carcinoma Cells In Vitro and In Vivo
by: Ruolan Chen, et al.
Published: (2025-01-01)

Naringin prevents heart mitochondria dysfunction during diabetic cardiomyopathy in rats
by: Ilya Zavodnik, et al.
Published: (2025-01-01)

circRNA CDR1as Regulated the Proliferation of Human Periodontal Ligament Stem Cells under a Lipopolysaccharide-Induced Inflammatory Condition
by: Fang Wang, et al.
Published: (2019-01-01)

The Protective Effect of Naringin against Bleomycin-Induced Pulmonary Fibrosis in Wistar Rats
by: Nergiz H. Turgut, et al.
Published: (2016-01-01)

METTL3-Mediated m6A Modification Regulates the Osteogenic Differentiation through LncRNA CUTALP in Periodontal Mesenchymal Stem Cells of Periodontitis Patients
by: Xin Chen, et al.
Published: (2024-01-01)

In Vitro Osteogenic Properties of Two Dental Implant Surfaces
by: Marta Monjo, et al.
Published: (2012-01-01)

Study on the protective effect of naringin-regulated lncRNA GAS5 against mitochondrial apoptosis in osteoarthritic chondrocytes
by: LIN Qin, et al.
Published: (2025-01-01)

Knockdown of RFC4 inhibits cell proliferation of oral squamous cell carcinoma in vitro and in vivo
by: Pengyue You, et al.
Published: (2025-02-01)

MEST Regulates the Stemness of Human Periodontal Ligament Stem Cells
by: Daigaku Hasegawa, et al.
Published: (2020-01-01)

Effects of Type 2 Diabetic Serum on Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells
by: Xiangqun Deng, et al.
Published: (2018-01-01)

LPS from P. gingivalis and Hypoxia Increases Oxidative Stress in Periodontal Ligament Fibroblasts and Contributes to Periodontitis
by: L. Gölz, et al.
Published: (2014-01-01)

EZH2 Regulates Lipopolysaccharide-Induced Periodontal Ligament Stem Cell Proliferation and Osteogenesis through TLR4/MyD88/NF-κB Pathway
by: Pengcheng Wang, et al.
Published: (2021-01-01)

Dose-dependent enhancement of in vitro osteogenic activity on strontium-decorated polyetheretherketone
by: Yongheng Zhang, et al.
Published: (2025-01-01)

Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue
by: Atsushi Tomokiyo, et al.
Published: (2018-01-01)

Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic Forces
by: L. Feller, et al.
Published: (2015-01-01)

Effect of Mechanical Force Stress on the Inflammatory Response in Human Periodontal Ligament Cells
by: Thira Rojasawasthien, et al.
Published: (2025-02-01)

Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy
by: Hemanathan Vembuli, et al.
Published: (2025-02-01)

Levistolide A and periplogenin inhibit the growth of gastric cancer cells in vitro and in vivo
by: Jia Li Guo, et al.
Published: (2023-03-01)

Efferocytosis-related gene IL33 predicts prognosis and immune response and mediates proliferation and migration in vitro and in vivo of breast cancer
by: Xiao He, et al.
Published: (2025-01-01)

Influence of surface texture on osteogenic differentiation of dental pulp stem cells: An in vitro study
by: Komal Rajpurohit, et al.
Published: (2024-07-01)

In Vitro Uptake of Hydroxyapatite Nanoparticles and Their Effect on Osteogenic Differentiation of Human Mesenchymal Stem Cells
by: Xing Yang, et al.
Published: (2018-01-01)

Effect of ozone oil and non-surgical periodontal treatment in patients with type 2 diabetes. In-vivo and in-vitro studies with fibroblasts and Candida albicans
by: Raquel Alves do CARMO, et al.
Published: (2025-01-01)

Human Periodontal Ligament Stem Cell-Derived Exosomes Promote Bone Regeneration by Altering MicroRNA Profiles
by: Ting Liu, et al.
Published: (2020-01-01)

Guanylate-Binding Protein 1 Promotes Migration and Invasion of Human Periodontal Ligament Stem Cells
by: Shi Bai, et al.
Published: (2018-01-01)

Erythrocyte Storage Lesion Improvements Mediated by Naringin Screened from Vegetable/Fruit Juice Using Cell Extract and HPLC-MS
by: Yuqi She, et al.
Published: (2022-01-01)

Fabrication of Core-Shell PEI/pBMP2-PLGA Electrospun Scaffold for Gene Delivery to Periodontal Ligament Stem Cells
by: Qiao Xie, et al.
Published: (2016-01-01)

Long-Term Stability and Osteogenic Activity of Recycled Polysulfone-Calcium Silicate Bone Implants In Vitro
by: Chi-Nan Chang, et al.
Published: (2025-01-01)

Semaphorin3B Promotes Proliferation and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in a High-Glucose Microenvironment
by: Quan Xing, et al.
Published: (2021-01-01)

Preparation and In Vitro/In Vivo Evaluation of Vinpocetine Elementary Osmotic Pump System
by: Meiying Ning, et al.
Published: (2011-01-01)

Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells
by: Yoshitaka Hosokawa, et al.
Published: (2021-01-01)

Comparison of Immunological Characteristics of Mesenchymal Stem Cells from the Periodontal Ligament, Umbilical Cord, and Adipose Tissue
by: Jin-Hee Kim, et al.
Published: (2018-01-01)