Antibacterial Activity of Sinularia sp. Against Escherichia coli and Staphylococcus aureus: Meta-Analysis and Systematic Review
The Ocean covers more than 70% of Indonesian archipelago, providing various bioactive compounds with great potential, however, it is relatively underexplored Sinularia sp, a genus of soft corals, exists at the coral reefs of Indo-Pacific ocean. Several recent studies have shown that Sinularia sp. co...
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| Format: | Article |
| Language: | Indonesian |
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LPPM STIKES Guna Bangsa Yogyakarta
2025-01-01
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| Series: | Journal of Health (JOH) |
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| Online Access: | https://journal.gunabangsa.ac.id/index.php/joh/article/view/1094 |
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| author | Deka Prismawan Monika Arvia Chiara Shannen Ivanka Gunardi Karmill Trinanda Robby Sutedjo Michael Michael |
| author_facet | Deka Prismawan Monika Arvia Chiara Shannen Ivanka Gunardi Karmill Trinanda Robby Sutedjo Michael Michael |
| author_sort | Deka Prismawan |
| collection | DOAJ |
| description | The Ocean covers more than 70% of Indonesian archipelago, providing various bioactive compounds with great potential, however, it is relatively underexplored Sinularia sp, a genus of soft corals, exists at the coral reefs of Indo-Pacific ocean. Several recent studies have shown that Sinularia sp. contains various types of secondary metabolites with antiviral, antibacterial, anticancer, and antimalarial properties. In addition, further exploration and discovery of novel antibacterials that are effective against wide spectrum of bacteria is of great interest, especially to combat the emerging antibiotic resistance. The aim of this study is to evaluate the potential of antibacterial activity from Sinularia sp against E. coli and S. aureus which in turn, may provide an alternative antibacterial to overcome the emerging antibiotic resistance. This study was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) statement to measure the effect size of the antibacterial activity from Sinularia sp. against E. coli and S. aureus. Estimated value of the effect size obtained is 2.52 (CI 95% 0.98 to 4.06) and 5.97 (CI 95% 3.18 to 8.77) towards E. coli and S. aureus. When viewed as a whole, published data appears to show a positive antibacterial effect from Sinularia sp. |
| format | Article |
| id | doaj-art-52e8e660cbb0406789cddb6657281ff9 |
| institution | Kabale University |
| issn | 2355-8857 2407-6376 |
| language | Indonesian |
| publishDate | 2025-01-01 |
| publisher | LPPM STIKES Guna Bangsa Yogyakarta |
| record_format | Article |
| series | Journal of Health (JOH) |
| spelling | doaj-art-52e8e660cbb0406789cddb6657281ff92025-02-03T00:51:08ZindLPPM STIKES Guna Bangsa YogyakartaJournal of Health (JOH)2355-88572407-63762025-01-0112109810610.30590/joh.v12n1.10941094Antibacterial Activity of Sinularia sp. Against Escherichia coli and Staphylococcus aureus: Meta-Analysis and Systematic ReviewDeka Prismawan0Monika Arvia Chiara1Shannen Ivanka Gunardi2Karmill Trinanda3Robby Sutedjo4Michael Michael5Universitas Katolik Indonesia Atma JayaUniversitas Katolik Indonesia Atma JayaUniversitas Katolik Indonesia Atma JayaUniversitas Katolik Indonesia Atma JayaUniversitas Katolik Indonesia Atma JayaUniversitas Katolik Indonesia Atma JayaThe Ocean covers more than 70% of Indonesian archipelago, providing various bioactive compounds with great potential, however, it is relatively underexplored Sinularia sp, a genus of soft corals, exists at the coral reefs of Indo-Pacific ocean. Several recent studies have shown that Sinularia sp. contains various types of secondary metabolites with antiviral, antibacterial, anticancer, and antimalarial properties. In addition, further exploration and discovery of novel antibacterials that are effective against wide spectrum of bacteria is of great interest, especially to combat the emerging antibiotic resistance. The aim of this study is to evaluate the potential of antibacterial activity from Sinularia sp against E. coli and S. aureus which in turn, may provide an alternative antibacterial to overcome the emerging antibiotic resistance. This study was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) statement to measure the effect size of the antibacterial activity from Sinularia sp. against E. coli and S. aureus. Estimated value of the effect size obtained is 2.52 (CI 95% 0.98 to 4.06) and 5.97 (CI 95% 3.18 to 8.77) towards E. coli and S. aureus. When viewed as a whole, published data appears to show a positive antibacterial effect from Sinularia sp.https://journal.gunabangsa.ac.id/index.php/joh/article/view/1094sinularia sp.antibacteriale. colis. aureusmeta-analysisantibiotic resistance |
| spellingShingle | Deka Prismawan Monika Arvia Chiara Shannen Ivanka Gunardi Karmill Trinanda Robby Sutedjo Michael Michael Antibacterial Activity of Sinularia sp. Against Escherichia coli and Staphylococcus aureus: Meta-Analysis and Systematic Review Journal of Health (JOH) sinularia sp. antibacterial e. coli s. aureus meta-analysis antibiotic resistance |
| title | Antibacterial Activity of Sinularia sp. Against Escherichia coli and Staphylococcus aureus: Meta-Analysis and Systematic Review |
| title_full | Antibacterial Activity of Sinularia sp. Against Escherichia coli and Staphylococcus aureus: Meta-Analysis and Systematic Review |
| title_fullStr | Antibacterial Activity of Sinularia sp. Against Escherichia coli and Staphylococcus aureus: Meta-Analysis and Systematic Review |
| title_full_unstemmed | Antibacterial Activity of Sinularia sp. Against Escherichia coli and Staphylococcus aureus: Meta-Analysis and Systematic Review |
| title_short | Antibacterial Activity of Sinularia sp. Against Escherichia coli and Staphylococcus aureus: Meta-Analysis and Systematic Review |
| title_sort | antibacterial activity of sinularia sp against escherichia coli and staphylococcus aureus meta analysis and systematic review |
| topic | sinularia sp. antibacterial e. coli s. aureus meta-analysis antibiotic resistance |
| url | https://journal.gunabangsa.ac.id/index.php/joh/article/view/1094 |
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