Purpuric pityriasis rosea in patients with anorexia nervosa
Pityriasis rosea (PR) is an exanthematous disease associated with the endogenous systemic reactivation of human herpesvirus (HHV)-6 and/or HHV-7. Variants of PR characterized by atypical lesion morphology, eruption course, and severe symptoms have already been described, but their prevalence is pro...
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PAGEPress Publications
2025-01-01
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| Series: | Dermatology Reports |
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| Online Access: | https://www.pagepress.org/journals/dr/article/view/10053 |
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| author | Giulia Ciccarese Antonio Guadagno Astrid Herzum Valentina Amicarelli Francesco Drago |
| author_facet | Giulia Ciccarese Antonio Guadagno Astrid Herzum Valentina Amicarelli Francesco Drago |
| author_sort | Giulia Ciccarese |
| collection | DOAJ |
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Pityriasis rosea (PR) is an exanthematous disease associated with the endogenous systemic reactivation of human herpesvirus (HHV)-6 and/or HHV-7. Variants of PR characterized by atypical lesion morphology, eruption course, and severe symptoms have already been described, but their prevalence is probably underestimated. We report herein two patients suffering from anorexia nervosa (AN) who developed a very rare form of purpuric PR. So far, no cases of PR in AN patients have been reported in the literature. In AN, impaired cell-mediated immunity may favor the endogenous systemic reactivation of HHV- 6 and/or HHV-7, causing PR. Furthermore, an increased level of the vascular cell adhesion molecule 1, interleukin 6, and tumor necrosis factor-α has been demonstrated in AN patients, which may be responsible for their increased vascular dysfunction.
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| format | Article |
| id | doaj-art-52e1d9d43b2c4b1896aed2eb2178ce7e |
| institution | Kabale University |
| issn | 2036-7392 2036-7406 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Dermatology Reports |
| spelling | doaj-art-52e1d9d43b2c4b1896aed2eb2178ce7e2025-01-21T01:43:12ZengPAGEPress PublicationsDermatology Reports2036-73922036-74062025-01-0110.4081/dr.2025.10053Purpuric pityriasis rosea in patients with anorexia nervosaGiulia Ciccarese0Antonio Guadagno1Astrid Herzum2Valentina Amicarelli3Francesco Drago4Section of Dermatology, Department of Medical and Surgical Sciences, University of FoggiaUnit of Pathology, IRCCS Ospedale Policlinico San Martino, GenoaDermatology Unit, IRCCS Istituto Giannina Gaslini, GenoaPrivate Practice, FoggiaDermatology Clinic, Casa di Cura Villa Montallegro, Genoa Pityriasis rosea (PR) is an exanthematous disease associated with the endogenous systemic reactivation of human herpesvirus (HHV)-6 and/or HHV-7. Variants of PR characterized by atypical lesion morphology, eruption course, and severe symptoms have already been described, but their prevalence is probably underestimated. We report herein two patients suffering from anorexia nervosa (AN) who developed a very rare form of purpuric PR. So far, no cases of PR in AN patients have been reported in the literature. In AN, impaired cell-mediated immunity may favor the endogenous systemic reactivation of HHV- 6 and/or HHV-7, causing PR. Furthermore, an increased level of the vascular cell adhesion molecule 1, interleukin 6, and tumor necrosis factor-α has been demonstrated in AN patients, which may be responsible for their increased vascular dysfunction. https://www.pagepress.org/journals/dr/article/view/10053Pityriasis roseapurpuric lesionsanorexia nervosa |
| spellingShingle | Giulia Ciccarese Antonio Guadagno Astrid Herzum Valentina Amicarelli Francesco Drago Purpuric pityriasis rosea in patients with anorexia nervosa Dermatology Reports Pityriasis rosea purpuric lesions anorexia nervosa |
| title | Purpuric pityriasis rosea in patients with anorexia nervosa |
| title_full | Purpuric pityriasis rosea in patients with anorexia nervosa |
| title_fullStr | Purpuric pityriasis rosea in patients with anorexia nervosa |
| title_full_unstemmed | Purpuric pityriasis rosea in patients with anorexia nervosa |
| title_short | Purpuric pityriasis rosea in patients with anorexia nervosa |
| title_sort | purpuric pityriasis rosea in patients with anorexia nervosa |
| topic | Pityriasis rosea purpuric lesions anorexia nervosa |
| url | https://www.pagepress.org/journals/dr/article/view/10053 |
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