Menopausal shift on women’s health and microbial niches

Abstract Menopause marks a key milestone in women’s aging, triggering hormonal, histological, and microbiome changes. This review explores how hormonal shifts during menopause alter the microbiome’s composition, affecting oral, intestinal, and urogenital communities, potentially leading to disease....

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Main Authors: Maria R. Nieto, Maria J. Rus, Victoria Areal-Quecuty, Daniel M. Lubián-López, Aurea Simon-Soro
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Women's Health
Online Access:https://doi.org/10.1038/s44294-024-00050-y
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author Maria R. Nieto
Maria J. Rus
Victoria Areal-Quecuty
Daniel M. Lubián-López
Aurea Simon-Soro
author_facet Maria R. Nieto
Maria J. Rus
Victoria Areal-Quecuty
Daniel M. Lubián-López
Aurea Simon-Soro
author_sort Maria R. Nieto
collection DOAJ
description Abstract Menopause marks a key milestone in women’s aging, triggering hormonal, histological, and microbiome changes. This review explores how hormonal shifts during menopause alter the microbiome’s composition, affecting oral, intestinal, and urogenital communities, potentially leading to disease. The microbial metabolism of sex hormones highlights the bidirectional relationship between hormones and the microbiome. Understanding this interplay is crucial for developing personalized interventions to restore microbial balance and improve women’s health during menopause.
format Article
id doaj-art-52da8d95b3574d58ba192de30a8fb728
institution Kabale University
issn 2948-1716
language English
publishDate 2025-01-01
publisher Nature Portfolio
record_format Article
series npj Women's Health
spelling doaj-art-52da8d95b3574d58ba192de30a8fb7282025-01-19T12:44:02ZengNature Portfolionpj Women's Health2948-17162025-01-013111110.1038/s44294-024-00050-yMenopausal shift on women’s health and microbial nichesMaria R. Nieto0Maria J. Rus1Victoria Areal-Quecuty2Daniel M. Lubián-López3Aurea Simon-Soro4Departamento de Estomatología, Facultad de Odontología, Universidad de SevillaDepartamento de Estomatología, Facultad de Odontología, Universidad de SevillaDepartamento de Estomatología, Facultad de Odontología, Universidad de SevillaDepartment of Obstetrics and Gynecology, University Hospital of Jerez de la FronteraDepartamento de Estomatología, Facultad de Odontología, Universidad de SevillaAbstract Menopause marks a key milestone in women’s aging, triggering hormonal, histological, and microbiome changes. This review explores how hormonal shifts during menopause alter the microbiome’s composition, affecting oral, intestinal, and urogenital communities, potentially leading to disease. The microbial metabolism of sex hormones highlights the bidirectional relationship between hormones and the microbiome. Understanding this interplay is crucial for developing personalized interventions to restore microbial balance and improve women’s health during menopause.https://doi.org/10.1038/s44294-024-00050-y
spellingShingle Maria R. Nieto
Maria J. Rus
Victoria Areal-Quecuty
Daniel M. Lubián-López
Aurea Simon-Soro
Menopausal shift on women’s health and microbial niches
npj Women's Health
title Menopausal shift on women’s health and microbial niches
title_full Menopausal shift on women’s health and microbial niches
title_fullStr Menopausal shift on women’s health and microbial niches
title_full_unstemmed Menopausal shift on women’s health and microbial niches
title_short Menopausal shift on women’s health and microbial niches
title_sort menopausal shift on women s health and microbial niches
url https://doi.org/10.1038/s44294-024-00050-y
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