The Improvement of Dry Eye Symptoms after Pinguecula Excision and Conjunctival Autograft with Fibrin Glue
Purpose. To evaluate the association between pinguecula excision and subsequent improvement in dry eye syndrome. Methods. We included 30 consecutive patients with primary nasal pinguecula and dry eye symptoms undergoing ocular surgery for the first time. Criteria for pinguecula excision surgery were...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2019/6438157 |
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| author | Jinho Jeong Gabriel M. Rand Taejung Kwon Ji-Won Kwon |
| author_facet | Jinho Jeong Gabriel M. Rand Taejung Kwon Ji-Won Kwon |
| author_sort | Jinho Jeong |
| collection | DOAJ |
| description | Purpose. To evaluate the association between pinguecula excision and subsequent improvement in dry eye syndrome. Methods. We included 30 consecutive patients with primary nasal pinguecula and dry eye symptoms undergoing ocular surgery for the first time. Criteria for pinguecula excision surgery were nasal location, yellowish color, and protrusion of conjunctiva at least 2 times thicker than adjacent normal conjunctiva as measured by anterior segment optical coherence tomography. Our primary outcomes were 3-month postoperative changes in tear film breakup time (TBUT), Schirmer test, and a dry eye symptom score. Results. 30 eyes from 30 different patients (12 men and 18 women) underwent pinguecula excision and conjunctival autografting using fibrin glue. The mean age was 42.5 ± 8.35 (range 28–63) years. The preoperative protrusion ratio of pinguecula was 2.33 ± 0.28 (range 2.00–2.90). Mean preoperative TBUT, Schirmer test, and dry eye symptom scores were 5.10 ± 1.27 seconds, 6.07 ± 2.27 mm, and 2.80 ± 0.76 points. Mean postoperative 3-month TBUT, Schirmer test, and dry eye symptom scores were 7.80 ± 1.13 seconds, 7.27 ± 2.02 mm, and 0.30 ± 0.47 points, respectively. The median pre- and postoperative changes were found to be statistically significant by Wilcoxon signed-rank tests for TBUT, Schirmer test score, and dry eye symptom score. Conclusion. Surgical excision of pinguecula and conjunctival autograft using fibrin glue is an effective and safe method to improve symptoms of dry eye syndrome. |
| format | Article |
| id | doaj-art-529409fbb15b4c9aa66b335452661b59 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-529409fbb15b4c9aa66b335452661b592025-02-03T00:59:27ZengWileyJournal of Ophthalmology2090-004X2090-00582019-01-01201910.1155/2019/64381576438157The Improvement of Dry Eye Symptoms after Pinguecula Excision and Conjunctival Autograft with Fibrin GlueJinho Jeong0Gabriel M. Rand1Taejung Kwon2Ji-Won Kwon3Department of Ophthalmology, Jeju National University College of Medicine, Jeju, Republic of KoreaDepartment of Ophthalmology and Visual Sciences, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY, USADepartment of Pathology, Myongji Hospital, Hanyang University College of Medicine, Goyang, Republic of KoreaDepartment of Ophthalmology, Myongji Hospital, Hanyang University College of Medicine, Goyang, Republic of KoreaPurpose. To evaluate the association between pinguecula excision and subsequent improvement in dry eye syndrome. Methods. We included 30 consecutive patients with primary nasal pinguecula and dry eye symptoms undergoing ocular surgery for the first time. Criteria for pinguecula excision surgery were nasal location, yellowish color, and protrusion of conjunctiva at least 2 times thicker than adjacent normal conjunctiva as measured by anterior segment optical coherence tomography. Our primary outcomes were 3-month postoperative changes in tear film breakup time (TBUT), Schirmer test, and a dry eye symptom score. Results. 30 eyes from 30 different patients (12 men and 18 women) underwent pinguecula excision and conjunctival autografting using fibrin glue. The mean age was 42.5 ± 8.35 (range 28–63) years. The preoperative protrusion ratio of pinguecula was 2.33 ± 0.28 (range 2.00–2.90). Mean preoperative TBUT, Schirmer test, and dry eye symptom scores were 5.10 ± 1.27 seconds, 6.07 ± 2.27 mm, and 2.80 ± 0.76 points. Mean postoperative 3-month TBUT, Schirmer test, and dry eye symptom scores were 7.80 ± 1.13 seconds, 7.27 ± 2.02 mm, and 0.30 ± 0.47 points, respectively. The median pre- and postoperative changes were found to be statistically significant by Wilcoxon signed-rank tests for TBUT, Schirmer test score, and dry eye symptom score. Conclusion. Surgical excision of pinguecula and conjunctival autograft using fibrin glue is an effective and safe method to improve symptoms of dry eye syndrome.http://dx.doi.org/10.1155/2019/6438157 |
| spellingShingle | Jinho Jeong Gabriel M. Rand Taejung Kwon Ji-Won Kwon The Improvement of Dry Eye Symptoms after Pinguecula Excision and Conjunctival Autograft with Fibrin Glue Journal of Ophthalmology |
| title | The Improvement of Dry Eye Symptoms after Pinguecula Excision and Conjunctival Autograft with Fibrin Glue |
| title_full | The Improvement of Dry Eye Symptoms after Pinguecula Excision and Conjunctival Autograft with Fibrin Glue |
| title_fullStr | The Improvement of Dry Eye Symptoms after Pinguecula Excision and Conjunctival Autograft with Fibrin Glue |
| title_full_unstemmed | The Improvement of Dry Eye Symptoms after Pinguecula Excision and Conjunctival Autograft with Fibrin Glue |
| title_short | The Improvement of Dry Eye Symptoms after Pinguecula Excision and Conjunctival Autograft with Fibrin Glue |
| title_sort | improvement of dry eye symptoms after pinguecula excision and conjunctival autograft with fibrin glue |
| url | http://dx.doi.org/10.1155/2019/6438157 |
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