Secondary Syphilis with Eosinophilia Complicated by Severe Jarisch–Herxheimer Reaction
It has long been acknowledged that syphilis is a disease with a diverse range of presentations. We herein describe a case of a young man who presented with fever, rash, and eosinophilia following the commencement of allopurinol, only to be diagnosed with secondary syphilis on histopathology. His tre...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2020/2150314 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832547078168903680 |
|---|---|
| author | Anthony Elias Kirsty Wark Dana Slape David Cook Kenneth Lee Genevieve Mckew |
| author_facet | Anthony Elias Kirsty Wark Dana Slape David Cook Kenneth Lee Genevieve Mckew |
| author_sort | Anthony Elias |
| collection | DOAJ |
| description | It has long been acknowledged that syphilis is a disease with a diverse range of presentations. We herein describe a case of a young man who presented with fever, rash, and eosinophilia following the commencement of allopurinol, only to be diagnosed with secondary syphilis on histopathology. His treatment was complicated by a severe exacerbation of his cutaneous eruption following the commencement of penicillin, likely secondary to a Jarisch–Herxheimer reaction, an entity often overlooked by clinicians managing syphilis. |
| format | Article |
| id | doaj-art-527533c4ea5848faa925d9ee9816f7b2 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-527533c4ea5848faa925d9ee9816f7b22025-02-03T06:46:08ZengWileyCase Reports in Infectious Diseases2090-66252090-66332020-01-01202010.1155/2020/21503142150314Secondary Syphilis with Eosinophilia Complicated by Severe Jarisch–Herxheimer ReactionAnthony Elias0Kirsty Wark1Dana Slape2David Cook3Kenneth Lee4Genevieve Mckew5Department of Microbiology & Infectious Diseases, Concord Repatriation General Hospital, Sydney, New South Wales, AustraliaDepartment of Dermatology, Concord Repatriation General Hospital, Sydney, New South Wales, AustraliaDepartment of Dermatology, Concord Repatriation General Hospital, Sydney, New South Wales, AustraliaDepartment of Dermatology, Concord Repatriation General Hospital, Sydney, New South Wales, AustraliaDepartment of Anatomical Pathology, Concord Repatriation General Hospital, Sydney, New South Wales, AustraliaDepartment of Microbiology & Infectious Diseases, Concord Repatriation General Hospital, Sydney, New South Wales, AustraliaIt has long been acknowledged that syphilis is a disease with a diverse range of presentations. We herein describe a case of a young man who presented with fever, rash, and eosinophilia following the commencement of allopurinol, only to be diagnosed with secondary syphilis on histopathology. His treatment was complicated by a severe exacerbation of his cutaneous eruption following the commencement of penicillin, likely secondary to a Jarisch–Herxheimer reaction, an entity often overlooked by clinicians managing syphilis.http://dx.doi.org/10.1155/2020/2150314 |
| spellingShingle | Anthony Elias Kirsty Wark Dana Slape David Cook Kenneth Lee Genevieve Mckew Secondary Syphilis with Eosinophilia Complicated by Severe Jarisch–Herxheimer Reaction Case Reports in Infectious Diseases |
| title | Secondary Syphilis with Eosinophilia Complicated by Severe Jarisch–Herxheimer Reaction |
| title_full | Secondary Syphilis with Eosinophilia Complicated by Severe Jarisch–Herxheimer Reaction |
| title_fullStr | Secondary Syphilis with Eosinophilia Complicated by Severe Jarisch–Herxheimer Reaction |
| title_full_unstemmed | Secondary Syphilis with Eosinophilia Complicated by Severe Jarisch–Herxheimer Reaction |
| title_short | Secondary Syphilis with Eosinophilia Complicated by Severe Jarisch–Herxheimer Reaction |
| title_sort | secondary syphilis with eosinophilia complicated by severe jarisch herxheimer reaction |
| url | http://dx.doi.org/10.1155/2020/2150314 |
| work_keys_str_mv | AT anthonyelias secondarysyphiliswitheosinophiliacomplicatedbyseverejarischherxheimerreaction AT kirstywark secondarysyphiliswitheosinophiliacomplicatedbyseverejarischherxheimerreaction AT danaslape secondarysyphiliswitheosinophiliacomplicatedbyseverejarischherxheimerreaction AT davidcook secondarysyphiliswitheosinophiliacomplicatedbyseverejarischherxheimerreaction AT kennethlee secondarysyphiliswitheosinophiliacomplicatedbyseverejarischherxheimerreaction AT genevievemckew secondarysyphiliswitheosinophiliacomplicatedbyseverejarischherxheimerreaction |