Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic Review
Thermophilic Campylobacter species are clinically important aetiologies of gastroenteritis in humans throughout the world. The colonization of different animal reservoirs by Campylobacter poses an important risk for humans through shedding of the pathogen in livestock waste and contamination of wate...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | International Journal of Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2020/2092478 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832546940751970304 |
|---|---|
| author | Noel Gahamanyi Leonard E. G. Mboera Mecky I. Matee Dieudonné Mutangana Erick V. G. Komba |
| author_facet | Noel Gahamanyi Leonard E. G. Mboera Mecky I. Matee Dieudonné Mutangana Erick V. G. Komba |
| author_sort | Noel Gahamanyi |
| collection | DOAJ |
| description | Thermophilic Campylobacter species are clinically important aetiologies of gastroenteritis in humans throughout the world. The colonization of different animal reservoirs by Campylobacter poses an important risk for humans through shedding of the pathogen in livestock waste and contamination of water sources, environment, and food. A review of published articles was conducted to obtain information on the prevalence and antimicrobial resistance (AMR) profiles of thermophilic Campylobacter species in humans and animals in sub-Saharan Africa (SSA). Electronic databases, namely, PubMed, Google Scholar, Research4life-HINARI Health, and Researchgate.net, were searched using the following search terms “thermophilic Campylobacter,” “Campylobacter jejuni,” “Campylobacter coli,” “diarrhea/diarrhoea,” “antimicrobial resistance,” “antibiotic resistance,” “humans,” “animals,” “Sub-Saharan Africa,” and “a specific country name.” Initially, a total of 614 articles were identified, and the lists of references were screened in which 22 more articles were identified. After screening, 33 articles on humans and 34 on animals and animal products were included in this review. In humans, Nigeria reported the highest prevalence (62.7%), followed by Malawi (21%) and South Africa (20.3%). For Campylobacter infections in under-five children, Kenya reported 16.4%, followed by Rwanda (15.5%) and Ethiopia (14.5%). The country-level mean prevalence in all ages and under-five children was 18.6% and 9.4%, respectively. The prevalence ranged from 1.7%–62.7% in humans and 1.2%–80% in animals. The most reported species were C. jejuni and C. coli. The AMR to commonly used antimicrobials ranged from 0–100% in both humans and animals. Poultry consumption and drinking surface water were the main risk factors for campylobacteriosis. The present review provides evidence of thermophilic Campylobacter occurrence in humans and animals and high levels of AMR in SSA, emphasizing the need for strengthening both national and regional multisectoral antimicrobial resistance standard surveillance protocols to curb both the campylobacteriosis burden and increase of antimicrobial resistance in the region. |
| format | Article |
| id | doaj-art-52642203457148feac34ff977fbdf22f |
| institution | Kabale University |
| issn | 1687-918X 1687-9198 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Microbiology |
| spelling | doaj-art-52642203457148feac34ff977fbdf22f2025-02-03T06:46:37ZengWileyInternational Journal of Microbiology1687-918X1687-91982020-01-01202010.1155/2020/20924782092478Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic ReviewNoel Gahamanyi0Leonard E. G. Mboera1Mecky I. Matee2Dieudonné Mutangana3Erick V. G. Komba4SACIDS Foundation for One Health, College of Veterinary Medicine and Biomedical Sciences, Sokoine University of Agriculture, P.O. Box 3015, Chuo Kikuu, Morogoro, TanzaniaSACIDS Foundation for One Health, College of Veterinary Medicine and Biomedical Sciences, Sokoine University of Agriculture, P.O. Box 3015, Chuo Kikuu, Morogoro, TanzaniaSchool of Medicine, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, Dar es Salaam, TanzaniaCollege of Science and Technology, University of Rwanda, P.O. Box 3900, Kigali, RwandaSACIDS Foundation for One Health, College of Veterinary Medicine and Biomedical Sciences, Sokoine University of Agriculture, P.O. Box 3015, Chuo Kikuu, Morogoro, TanzaniaThermophilic Campylobacter species are clinically important aetiologies of gastroenteritis in humans throughout the world. The colonization of different animal reservoirs by Campylobacter poses an important risk for humans through shedding of the pathogen in livestock waste and contamination of water sources, environment, and food. A review of published articles was conducted to obtain information on the prevalence and antimicrobial resistance (AMR) profiles of thermophilic Campylobacter species in humans and animals in sub-Saharan Africa (SSA). Electronic databases, namely, PubMed, Google Scholar, Research4life-HINARI Health, and Researchgate.net, were searched using the following search terms “thermophilic Campylobacter,” “Campylobacter jejuni,” “Campylobacter coli,” “diarrhea/diarrhoea,” “antimicrobial resistance,” “antibiotic resistance,” “humans,” “animals,” “Sub-Saharan Africa,” and “a specific country name.” Initially, a total of 614 articles were identified, and the lists of references were screened in which 22 more articles were identified. After screening, 33 articles on humans and 34 on animals and animal products were included in this review. In humans, Nigeria reported the highest prevalence (62.7%), followed by Malawi (21%) and South Africa (20.3%). For Campylobacter infections in under-five children, Kenya reported 16.4%, followed by Rwanda (15.5%) and Ethiopia (14.5%). The country-level mean prevalence in all ages and under-five children was 18.6% and 9.4%, respectively. The prevalence ranged from 1.7%–62.7% in humans and 1.2%–80% in animals. The most reported species were C. jejuni and C. coli. The AMR to commonly used antimicrobials ranged from 0–100% in both humans and animals. Poultry consumption and drinking surface water were the main risk factors for campylobacteriosis. The present review provides evidence of thermophilic Campylobacter occurrence in humans and animals and high levels of AMR in SSA, emphasizing the need for strengthening both national and regional multisectoral antimicrobial resistance standard surveillance protocols to curb both the campylobacteriosis burden and increase of antimicrobial resistance in the region.http://dx.doi.org/10.1155/2020/2092478 |
| spellingShingle | Noel Gahamanyi Leonard E. G. Mboera Mecky I. Matee Dieudonné Mutangana Erick V. G. Komba Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic Review International Journal of Microbiology |
| title | Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic Review |
| title_full | Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic Review |
| title_fullStr | Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic Review |
| title_full_unstemmed | Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic Review |
| title_short | Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic Review |
| title_sort | prevalence risk factors and antimicrobial resistance profiles of thermophilic campylobacter species in humans and animals in sub saharan africa a systematic review |
| url | http://dx.doi.org/10.1155/2020/2092478 |
| work_keys_str_mv | AT noelgahamanyi prevalenceriskfactorsandantimicrobialresistanceprofilesofthermophiliccampylobacterspeciesinhumansandanimalsinsubsaharanafricaasystematicreview AT leonardegmboera prevalenceriskfactorsandantimicrobialresistanceprofilesofthermophiliccampylobacterspeciesinhumansandanimalsinsubsaharanafricaasystematicreview AT meckyimatee prevalenceriskfactorsandantimicrobialresistanceprofilesofthermophiliccampylobacterspeciesinhumansandanimalsinsubsaharanafricaasystematicreview AT dieudonnemutangana prevalenceriskfactorsandantimicrobialresistanceprofilesofthermophiliccampylobacterspeciesinhumansandanimalsinsubsaharanafricaasystematicreview AT erickvgkomba prevalenceriskfactorsandantimicrobialresistanceprofilesofthermophiliccampylobacterspeciesinhumansandanimalsinsubsaharanafricaasystematicreview |